Outcomes of Colorectal Dysplasia and Cancer in Patients with PSC-IBD Undergoing Liver Transplantation and Colectomy: Insights from a Multicenter Study

Outcomes of Colorectal Dysplasia and Cancer in Patients with PSC-IBD Undergoing Liver Transplantation and Colectomy: Insights from a Multicenter Study

This multicenter retrospective study examines colorectal dysplasia and malignancy outcomes in patients with primary sclerosing cholangitis and inflammatory bowel disease undergoing liver transplantation and colectomy, revealing comparable 5-year survival despite advanced disease in those transplanted first.
Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio

Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio

Plasma phosphorylated tau biomarkers overlap in Alzheimer’s and prion diseases, risking diagnostic confusion. The NfL/p-tau217 ratio emerges as an accurate plasma biomarker to distinguish prion diseases from Alzheimer’s, improving diagnostic precision and guiding appropriate clinical management.
Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

This article examines real-world data on low-dose antithymocyte globulin in type 1 diabetes, assessing beta-cell function via a novel C-peptide modified quantitative response (mQR). Findings suggest feasibility, safety, and potential clinical benefit in preserving endogenous insulin secretion.