Medxy AI

Retinal Microvascular Clues to Alzheimer Disease: What Swept-Source OCT Angiography Reveals About Neurovascular Dysfunction

By MedXY 06/19/2026

SS-OCTA identified retinal and choriocapillaris microvascular changes associated with cognitive status in Alzheimer disease, including thinner GCC in dementia and a biphasic CCFD pattern, suggesting a promising noninvasive biomarker platform.

news Ophthalmology Psychiatry

Calm in the Clinic? Digital Mindfulness Shows Promise for Anxiety and Depression in Non-infectious Uveitis

By MedXY 06/18/2026

A randomized trial found that an 8-week digital mindfulness app improved anxiety, depression, and stress in adults with non-infectious uveitis, but did not significantly change vision-related quality of life.

news Oncology Otorhinolaryngology

MDASI-HN Symptom Profiling for Early Risk Stratification of Hypoglossal Neuropathy in Oropharyngeal Cancer Survivors

By MedXY 06/18/2026

This study found that patient-reported speech/voice and related head-and-neck symptoms can help predict hypoglossal neuropathy risk after oropharyngeal cancer treatment, supporting earlier surveillance with the MDASI-HN-NERVE score.

news Otorhinolaryngology Pediatrics

Low-Yield or High-Value? Preoperative Cardiac Workup in Children With Very Severe OSA

By MedXY 06/18/2026

Preoperative cardiac testing in children with very severe OSA had low diagnostic yield and rarely changed management. Risk appeared highest in obese adolescents with AHI >50 events/hour.

General Surgery news Orthopedics

Postoperative Outcomes of Morel-Lavallée Injuries and Predictive Factors for Wound Complications

By MedXY 06/18/2026

A multicenter trauma study found that 20.1% of surgically treated Morel-Lavallée lesions developed wound complications. Pedestrian-versus-vehicle injury was the only independent predictor of postoperative problems.

Gastroenterology news Oncology

Immune Checkpoint Inhibitors Deliver Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

By MedXY 06/18/2026

MSI-H/dMMR gastroesophageal adenocarcinoma showed high response rates to immune checkpoint inhibitors, including durable complete responses in locoregional disease that may support carefully selected nonoperative management.

Gastroenterology news Oncology

Checkpoint Blockade Delivers Deep, Durable Responses in MSI-H Gastroesophageal Adenocarcinoma

By MedXY 06/18/2026

This single-center cohort found high and durable checkpoint inhibitor responses in dMMR/MSI-H gastroesophageal adenocarcinoma, including complete responses in locoregional disease that may support carefully selected nonoperative management.

Diabetes & Endocrinology news Oncology

GLP-1 Receptor Agonists May Outperform Bariatric Surgery for Breast Cancer Outcomes in Obese Postmenopausal Women

By MedXY 06/18/2026

In a large TriNetX study, GLP-1 receptor agonists were associated with better overall survival and lower locoregional recurrence than bariatric surgery alone in obese postmenopausal women with stage 0-III breast cancer.

Hematology-Oncology news OB/GYN & Women’s Health

GLP-1 Receptor Agonists May Outperform Bariatric Surgery in Obese Postmenopausal Breast Cancer Patients, Study Suggests

By MedXY 06/18/2026

A large real-world study found GLP-1 receptor agonists were associated with better survival and lower locoregional recurrence than bariatric surgery in postmenopausal women with obesity and breast cancer.

news OB/GYN & Women’s Health Oncology

Prehabilitation During Neoadjuvant Chemotherapy May Improve Surgery Eligibility and Chemotherapy Delivery in Advanced Ovarian Cancer

By MedXY 06/18/2026

A matched-cohort study found that multimodal prehabilitation during neoadjuvant chemotherapy improved chemotherapy delivery and increased the chance of interval debulking surgery in advanced ovarian cancer, with the strongest benefits seen in patients aged 70 and older.

news OB/GYN & Women’s Health Pediatrics

When the Prenatal Ultrasound “Level” Does Not Match the Neurologic Reality: Mapping Anatomical-Motor Discordance in Open Spinal Dysraphism

By MedXY 06/18/2026

In 187 fetuses with open spinal dysraphism, prenatal motor level was more caudal than the anatomical level in 85% of cases, with larger gaps in myeloschisis and higher lesions.

news OB/GYN & Women’s Health Pediatrics

Why the Spinal Lesion Level on Prenatal Ultrasound Often Does Not Match Fetal Motor Function

By MedXY 06/18/2026

Prenatal ultrasound in open spinal dysraphism often underestimates functional level: in 85% of fetuses, motor level was more caudal than anatomy. Lesion type and height influenced the gap, with implications for counseling and fetal care planning.

news OB/GYN & Women’s Health

From Symptoms to Preferences: Q-Methodology Maps What Women With Chronic Pelvic Pain Want From Treatment

By MedXY 06/18/2026

A Q-methodology study translated chronic pelvic pain experiences into five patient preference profiles to better align counseling and treatment selection with what matters most to patients.

Infectious Diseases news OB/GYN & Women’s Health

Hantavirus in Pregnancy: Why Obstetricians Need a High Index of Suspicion

By MedXY 06/17/2026

Hantavirus infection in pregnancy is rare but potentially fatal. Obstetricians should suspect it after rodent or travel exposure, recognize rapid respiratory decline, and prioritize supportive critical care because no proven antiviral therapy exists.

Gastroenterology Internal Medicine news

Lower-Dose Vitamin E Works as Well as Higher Doses in MASLD, VEDS Trial Finds

By MedXY 06/17/2026

In adults with suspected MASH, 200 IU/day vitamin E lowered ALT as effectively as 400 IU/day and 800 IU/day over 24 weeks, with no short-term safety signal, supporting lower-dose use if vitamin E is chosen.

Gastroenterology news Oncology

SPP1-Positive Macrophages Shape Immunosuppression in Colorectal Cancer Lymph Nodes

By MedXY 06/17/2026

Single-cell profiling of colorectal cancer lymph nodes revealed an SPP1–CD44–NF-κB1 pathway that promotes CD137+ regulatory T-cell maturation and may be therapeutically targetable.

Gastroenterology news Public Health

Validated Early Detection Metrics Could Narrow Liver Fibrosis Screening Without Losing Clinical Signal

By MedXY 06/17/2026

A validation study suggests current liver fibrosis screening criteria are too broad. A refined risk-based approach reduced eligibility from 60–76% to 10–22% of adults while improving the yield of elevated liver stiffness and predicting future liver events.

news Pediatrics

New Consensus Maps the Future of Pediatric Stroke Rehabilitation in Australia and New Zealand

By MedXY 06/17/2026

A modified Delphi study reached regional consensus on the most important outcomes and measurement tools for pediatric stroke rehabilitation, highlighting practical ways to standardize care and research across Australasia.

Neurology news

A New Way to Measure Prodromal Synucleinopathy: What the PSRS Adds for RBD Clinical Trials

By MedXY 06/17/2026

The PSRS showed good-to-excellent reliability and moderate-to-strong construct validity in a large RBD cohort, supporting its use as a multidomain measure of prodromal synucleinopathy burden.

Neurology news Public Health

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

By MedXY 06/17/2026

The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who responds best.