Medxy AI

Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum: A Randomized Clinical Trial

By MedXY 05/11/2026

A clinical trial found that weekly extended-release buprenorphine significantly improves illicit opioid abstinence during pregnancy compared to sublingual forms, with fewer serious adverse events, offering a safer treatment option for opioid use disorder.

Internal Medicine news Psychiatry

Initiation of Medications for Alcohol Use Disorder Among Hospitalized Veterans : A Retrospective Cohort Study

By MedXY 05/11/2026

VHA study reveals only 30% of veterans hospitalized for AUD receive evidence-based medications during or shortly after hospitalization, with significant variation across hospitals and demographic factors influencing prescription rates.

Hematology-Oncology news Oncology

Molecular Profiling Refines Relapse Risk After Allogeneic Transplant in First-Remission Acute Myeloid Leukemia

By MedXY 05/11/2026

A PETHEMA registry study shows that specific mutations, especially DNMT3A, SF3B1, TP53, and WT1, meaningfully refine relapse-free survival after allo-HSCT in first-remission AML beyond ELN risk groups.

Dermatology Hematology-Oncology news

A New CTCL-Specific Quality-of-Life Tool Shows Strong Early Validity Signals in Cutaneous T-Cell Lymphoma

By MedXY 05/11/2026

A single-center validation study suggests the CTCL-PRO-20 may provide a reliable, disease-specific measure of quality of life in patients with cutaneous T-cell lymphoma.

Hematology-Oncology news

CAR T-Cell Therapy Targeting CD117 Shows Promise Against Advanced Systemic Mastocytosis in Preclinical Studies

By MedXY 05/11/2026

Anti-CD117 CAR T-cell therapy demonstrated potent elimination of malignant mast cells in preclinical models of advanced systemic mastocytosis, offering a potential new treatment approach for this aggressive disorder.

Hematology-Oncology news Oncology

Study Finds Infusion Timing Does Not Affect CAR T-Cell Therapy Outcomes for Large B-Cell Lymphoma

By MedXY 05/11/2026

A retrospective study of 584 Australian lymphoma patients shows no significant link between CAR T-cell infusion timing and treatment outcomes, suggesting chronobiology may not influence results in large B-cell lymphoma therapy.

Cardiology news Respiratory

A GOLD Science Committee Perspective on Exacerbations and Cardiovascular Risk In COPD

By MedXY 05/11/2026

COPD exacerbations significantly increase cardiovascular risk for months. This article examines the link between COPD and heart disease, emphasizing proactive screening during flare-ups and evidence-based prevention strategies to improve survival rates.

news Ophthalmology

Genotype-phenotype correlations in RPGRIP1-associated retinal dystrophy in a nationwide Japanese cohort

By MedXY 05/11/2026

Study identifies distinct clinical patterns in Japanese patients with RPGRIP1 mutations: Leber congenital amaurosis shows severe early vision loss while achromatopsia features progressive degeneration. Exon 18 deletion emerges as a founder variant.

news Ophthalmology Pediatrics

Web-Based Amblyopia Decision Support Tool

By MedXY 05/11/2026

The Amblyopia Navigator offers evidence-based guidance for eye care professionals to improve early detection and treatment of childhood amblyopia, addressing specialist shortages through accessible digital tools.

Clinical Updates news

Clobetasol Propionate Ophthalmic Suspension 0.05%: A New Therapeutic Milestone in Post-Cataract Surgery Inflammation and Pain Management

By MedXY 05/11/2026

This review synthesizes clinical evidence for CPN 0.05% (BYQLOVI®), highlighting its rapid efficacy, superior pain resolution, and favorable safety profile compared to traditional ocular steroids following cataract surgery.

news Otorhinolaryngology Psychiatry

A CBT-Based Mobile App Significantly Reduced Tinnitus Distress in a Sham-Controlled Randomized Trial

By MedXY 05/11/2026

In a 60-patient randomized trial, a digital therapeutic app delivering tinnitus education and CBT elements produced large, durable reductions in tinnitus-related distress over 16 weeks, with no serious safety concerns.

news Otorhinolaryngology

3D-Printed Temporal Bones Provide a Reliable, Objective Way to Assess Mastoidectomy Skill Across Otolaryngology Training

By MedXY 05/11/2026

A prospective single-center study found that final product analysis on 3D-printed temporal bones reliably distinguished mastoidectomy performance by residency level and may support competency-based assessment.

Diabetes & Endocrinology General Surgery news

Adrenalectomy for Mild Autonomous Cortisol Secretion Was Linked to Lower Mortality, but the Survival Signal Requires Cautious Interpretation

By MedXY 05/11/2026

In a multi-institutional retrospective cohort, adrenalectomy for mild autonomous cortisol secretion was associated with lower mortality and less new-onset diabetes than nonoperative care, although sensitivity analysis weakened the survival finding.

Diabetes & Endocrinology General Surgery news

Biliopancreatic Diversion for Severe Obesity: Landmark 50-Year Study Reveals Lifelong Benefits and Risks

By MedXY 05/11/2026

A 50-year follow-up of biliopancreatic diversion shows sustained weight loss and diabetes remission, but alarmingly high nutritional complications decades after surgery.

news OB/GYN & Women’s Health Oncology

Estrogen Therapy Linked to Improved Survival in Certain Ovarian Cancer Patients Under 60

By MedXY 05/11/2026

Study shows post-diagnosis estrogen therapy improves survival in high-grade serous and clear cell ovarian cancers but may worsen outcomes in endometrioid subtypes, offering guidance for managing menopausal symptoms in younger survivors.

news OB/GYN & Women’s Health Public Health

Low-Dose Aspirin’s Pregnancy Benefit Appears Unchanged by Start Time or Adherence in a Large Multicentre Post Hoc Trial Analysis

By MedXY 05/11/2026

In this post hoc analysis of a large randomized pregnancy trial, aspirin’s effects on preterm birth and perinatal mortality were not meaningfully modified by gestational age at initiation or measured adherence.

Infectious Diseases news OB/GYN & Women’s Health

First-Trimester Maternal CMV Infection Concentrates the Risk of Fetal Brain Injury, Hearing Loss, and Autism Spectrum Disorder

By MedXY 05/11/2026

A large prospective cohort suggests that long-term sequelae of congenital CMV after primary maternal infection are confined to first-trimester exposure, with autism spectrum disorder linked to temporal lobe white matter abnormalities.

Gastroenterology news Oncology

A Body Surface Area–Adjusted Bevacizumab Target Was Linked to Better Survival in Atezolizumab-Treated Unresectable Hepatocellular Carcinoma

By MedXY 05/10/2026

A nationwide Japanese real-world study suggests that a defined body surface area–adjusted bevacizumab exposure range may improve progression-free and overall survival in unresectable HCC treated with atezolizumab plus bevacizumab, without increasing toxicity.

Gastroenterology news Oncology

A Stromal CTHRC1 Biomarker Framework May Identify Colorectal Cancers With Poor Prognosis and Limited Immunotherapy Benefit

By MedXY 05/10/2026

A large multiomic colorectal cancer study identifies CTHRC1-positive fibroblasts as a stromal biomarker linked to TGF-beta activity, adverse outcomes, and reduced checkpoint inhibitor benefit across both MSI and MSS disease.

Neurology news Public Health

Weak Grip, Slow Walking Pace, and Sarcopenia Signal Higher Risk of Incident Stroke and Worse Poststroke Survival in UK Biobank

By MedXY 05/10/2026

In nearly 483,000 UK Biobank participants, sarcopenia, low grip strength, and slow walking pace were associated with higher risks of incident stroke and poorer survival after stroke.