Medxy AI

Enhancing Post-Stroke Physical Activity Through Telehealth and Wearable Technology: A Feasibility Randomised Controlled Trial

By MedXY 10/25/2026

A feasibility RCT demonstrates that a telehealth-delivered behaviour change intervention, augmented with a physical activity monitor, can increase physical activity in post-stroke individuals, supporting future large-scale trials.

Dentistry news

Advancing Dental Education: Repair Versus Replacement of Defective Composite Restorations in Canadian Dental Schools

By MedXY 10/25/2026

A comprehensive assessment of the teaching practices regarding repair and replacement of defective composite restorations in Canadian dental schools highlights the move towards minimally invasive dentistry and calls for harmonization of educational standards.

Clinical Updates news Public Health

Immunogenicity and Safety of Fractional 17DD Yellow Fever Vaccine Doses in Young Children: Evidence from a Phase 4 Randomised Trial in Uganda and Broader Context

By MedXY 10/25/2026

Fractional doses (one-fifth and one-half) of 17DD yellow fever vaccine demonstrate non-inferior immunogenicity and comparable safety to full doses in children aged 9–23 months, supporting dose-sparing strategies during vaccine shortages.

Emergency Medicine news Pediatrics

Enhancing Prehospital Pediatric Ventilation Quality with Real-Time Feedback Devices: Insights from a Randomized Study

By MedXY 10/25/2026

A randomized crossover study reveals that manual ventilation quality in pediatric respiratory arrest is suboptimal among EMS clinicians, but use of a ventilation feedback device significantly improves adherence to pediatric ventilation guidelines.

news Respiratory Rheumatology

Nerandomilast Shows Promise in Slowing Progressive Pulmonary Fibrosis in Autoimmune Disease: Insights from the FIBRONEER-ILD Trial

By MedXY 10/25/2026

The FIBRONEER-ILD trial demonstrates nerandomilast’s potential to slow lung function decline and reduce mortality in patients with autoimmune-related progressive pulmonary fibrosis, with a favorable safety profile.

news Respiratory

Long-Term Proton Pump Inhibitor Use Post-Lung Transplantation: Near-Universal but No Clear Benefit on Clinical Outcomes Over Two Decades

By MedXY 10/25/2026

A 20-year observational study reveals near-universal long-term proton pump inhibitor use in lung transplant recipients without demonstrable improvements in graft function or survival, challenging routine PPI prescriptions in this population.

Allergy & Immunology Dermatology news

Ivarmacitinib Shows Promising Rapid Efficacy and Immune Modulation in Palmoplantar Pustulosis: Insights from a Multicenter Clinical Trial

By MedXY 10/25/2026

Ivarmacitinib, a selective JAK1 inhibitor, demonstrated rapid efficacy and immune remodeling in palmoplantar pustulosis over 12 weeks, with favorable safety and potential biomarkers for response stratification.

Anesthesiology news Plastic Surgery

Outpatient Lipoabdominoplasty Using Sedation, TAP Block, and Tumescent Anesthesia: A Safe and Effective Pain Management Strategy

By MedXY 10/25/2026

This study demonstrates that lipoabdominoplasty performed under sedation with TAP block and tumescent anesthesia is safe, effective, and feasible in an outpatient setting, offering excellent pain control, minimal nausea, and high patient satisfaction.

Clinical Updates Critical Care news

Association of Tele-Critical Care Capability With Interhospital Transfers and Potentially Low-Value Transfers Among Critically Ill Medicare Beneficiaries: A Nationwide Evidence Synthesis

By MedXY 10/25/2026

This review synthesizes evidence linking tele-critical care with interhospital transfer patterns and outcomes, highlighting improved transfer selection and reduced low-value transfers among critically ill Medicare patients.

Internal Medicine news Superintelligence

Enhancing Ambulatory Care: Patient Experiences with Ambient AI Scribes

By MedXY 10/25/2026

This qualitative study explores how ambient AI scribes affect ambulatory patient experience, revealing improvements in communication, visit thoroughness, and patient comfort influenced by demographic and relational factors.

Clinical Updates Hematology-Oncology news

Combining Midostaurin with Low-Dose Cytarabine and Venetoclax in Older Adults with Newly Diagnosed AML: Evidence and Implications from the INTERVENE Phase 2 Trial

By MedXY 10/25/2026

The INTERVENE trial reveals that adding midostaurin to low-dose cytarabine and venetoclax is tolerable and improves FLT3-ITD clearance and survival in older AML patients with FLT3-ITD, addressing resistance in this high-risk subgroup.

news OB/GYN & Women's Health Respiratory

Fertility, Pregnancy, and Women’s Health in Bronchiectasis: Insights from a Multicenter Study and Global Patient Survey

By MedXY 10/25/2026

Women with bronchiectasis face unique reproductive challenges, particularly those with primary ciliary dyskinesia (PCD). Pregnancy often involves exacerbations, but neonatal outcomes remain generally favorable with proper pulmonary care.

news Ophthalmology

Optimizing Intraocular Lens Power Calculations in Extremely Long Eyes: The Role of Axial Length Adjustment and AL/R Ratio

By MedXY 10/25/2026

This study highlights the superiority of the Holladay 1 formula combined with Wang-Koch axial length adjustment in predicting refractive outcomes in eyes with axial length ≥30 mm, introducing the AL-to-corneal radius ratio as a novel stratification biomarker to improve IOL power calculations.

Neurology news Otorhinolaryngology

Neurotologic and 3D-FLAIR MRI Correlates in Idiopathic Acute Unilateral Audiovestibulopathy: Advancing Diagnosis and Understanding

By MedXY 10/25/2026

MRI positivity in 52% of idiopathic acute unilateral audiovestibulopathy patients correlates significantly with vestibular deficits, particularly in the posterior canal, aiding diagnostic clarity and revealing pathophysiological insights.

General Surgery news

Mesh Position Matters: Patient-Reported Outcomes After Elective Incisional Hernia Repair in a Danish Nationwide Cohort

By MedXY 10/25/2026

A large Danish study evaluates how mesh placement during incisional hernia repair affects patient-reported outcomes, finding increased foreign body sensation with onlay mesh but no differences in chronic pain or recurrence.

news OB/GYN & Women's Health Pediatrics

Prenatal Maternal Phosphatidylcholine and Children’s Behavior and Cognition through 4 Years of Age: Randomized Clinical Trial

By MedXY 10/25/2026

A randomized clinical trial shows prenatal phosphatidylcholine supplements support fetal brain development, reducing early childhood social withdrawal and improving cognitive performance without significant safety concerns.

Internal Medicine Neurology news

Vascular Risk Factors as Key Contributors to Late-Onset Epilepsy: Insights from a Large US Cohort Meta-Analysis

By MedXY 10/25/2026

A comprehensive meta-analysis of six US cohorts identifies vascular risk factors including smoking, hypertension, diabetes, chronic kidney disease, stroke history, and APOE ε4 genotype as significant predictors of late-onset epilepsy in older adults.

Diabetes & Endocrinology news

Setmelanotide Therapy Reduces Metabolic Syndrome Risk in Patients with POMC or LEPR Deficiencies

By MedXY 10/25/2026

Setmelanotide, an MC4R agonist, improves metabolic parameters and reduces metabolic syndrome severity in patients with POMC or LEPR deficiencies causing severe obesity, after one year of treatment.

Cardiology Critical Care news

Unraveling sST2’s Role in Fulminant Myocarditis: A Novel Mitochondrial Therapeutic Axis

By MedXY 10/25/2026

Elevated soluble ST2 worsens fulminant myocarditis by impairing cardiomyocyte mitochondria via IGF2R-YY1, providing a new prognostic biomarker and therapeutic target.

news Orthopedics

Early Quadriceps Strength Recovery Predicts 2-Year Outcomes After Quadriceps Tendon Autograft ACL Reconstruction

By MedXY 10/25/2026

Early postoperative quadriceps strength symmetry strongly predicts patient-reported knee function and satisfaction two years after quadriceps tendon autograft ACL reconstruction, highlighting its role in guiding rehabilitation and assessing recovery milestones.