Youth with Histories of Out-of-Home Placement Face Significantly Longer Emergency Department Stays and Higher Restraint Rates During Mental Health Crises

Youth with Histories of Out-of-Home Placement Face Significantly Longer Emergency Department Stays and Higher Restraint Rates During Mental Health Crises

A retrospective study at Mayo Clinic reveals that children with a history of out-of-home placement experience 24% longer ED stays and double the odds of physical or pharmacological restraint during psychiatric emergencies compared to their peers, highlighting critical systemic disparities in pediatric mental health care.
Semaglutide Mitigates Cardiometabolic Risk in Early-Stage Schizophrenia: Insights from a Randomized Clinical Trial

Semaglutide Mitigates Cardiometabolic Risk in Early-Stage Schizophrenia: Insights from a Randomized Clinical Trial

A landmark RCT demonstrates that adjunctive semaglutide significantly improves glycemic control and induces substantial weight loss in individuals with schizophrenia spectrum disorders treated with second-generation antipsychotics, potentially closing the mortality gap in this high-risk population.
AI-Driven Detection of Extranodal Extension Outperforms Radiologists in Predicting Outcomes for HPV-Positive Oropharyngeal Cancer

AI-Driven Detection of Extranodal Extension Outperforms Radiologists in Predicting Outcomes for HPV-Positive Oropharyngeal Cancer

A single-center study demonstrates that an AI pipeline for CT-based lymph node segmentation and extranodal extension classification significantly improves prognostic accuracy for HPV-positive oropharyngeal cancer compared to traditional radiological assessment, identifying high-risk patients more effectively.
Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management

Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management

This randomized clinical trial demonstrates that real acupuncture significantly reduces migraine frequency and disability compared to sham acupuncture. Crucially, baseline brain connectivity patterns within the default mode and subcortical networks can predict individual treatment responses, offering a potential biomarker for personalized neuromodulatory therapy.