Angiographic Burden of Coronary Atherosclerosis: The Critical Mediator Between ASCVD Risk Factors and Cardiovascular Outcomes
Posted inCardiology Internal Medicine news

Angiographic Burden of Coronary Atherosclerosis: The Critical Mediator Between ASCVD Risk Factors and Cardiovascular Outcomes

This Mendelian randomization study reveals that coronary plaque burden significantly mediates the link between traditional risk factors and adverse events like myocardial infarction and heart failure, reinforcing the necessity of early primary prevention to intercept atherosclerosis development.
Sex, Race, and Ancestry Converge to Shape Amyloid Pathology: Evidence from a Large-Scale Admixed Autopsy Study
Posted inNeurology news Pathology & Lab Medicine/Bệnh học

Sex, Race, and Ancestry Converge to Shape Amyloid Pathology: Evidence from a Large-Scale Admixed Autopsy Study

This cross-sectional study of 2,268 autopsies reveals that female sex, APOEε4 status, and African ancestry independently and jointly influence neuritic plaque burden, suggesting that current Alzheimer’s biomarker thresholds may need refinement to account for sex and ancestral diversity.
Global Variations in Patient Radiation Exposure for Coronary Artery Disease Diagnosis: A Synthesized Review of the INCAPS 4 Findings
Posted inClinical Updates news

Global Variations in Patient Radiation Exposure for Coronary Artery Disease Diagnosis: A Synthesized Review of the INCAPS 4 Findings

This review analyzes global radiation doses in CAD diagnostic imaging based on the INCAPS 4 study. It highlights significant disparities across modalities and regions, revealing that patients in low-income countries and those undergoing CCTA face substantially higher radiation risks, necessitating urgent standardized protocols.