Medxy AI

Technology-Guided Diet Counseling Training Enhances Resident Physicians’ Shared Decision-Making Skills in Primary Care

By MedXY 08/26/2026

Technology-guided diet counseling training using the Nutri platform improves resident physicians' attitudes, self-efficacy, and intention to discuss diet, facilitating shared decision making in routine primary care.

Diabetes & Endocrinology news Pathology & Lab Medicine/Bệnh học

Plasma POMC as a Predictive Biomarker for Silent Corticotroph Adenomas in Non-Functioning Pituitary Tumors

By MedXY 08/26/2026

Elevated plasma pro-opiomelanocortin (POMC) levels accurately predict silent corticotroph adenomas (SCAs) among clinically non-functioning pituitary adenomas, offering a promising tool for diagnosis and monitoring.

Hematology-Oncology news

TP53-Mutated Clonal Hematopoiesis Drives Pro-Inflammatory Phenotype and Predicts Poor Outcomes After CAR T-Cell Therapy

By MedXY 08/26/2026

TP53-mutant clonal hematopoiesis in CAR T-cell recipients is linked to a pro-inflammatory state, cytopenias, and worse survival, highlighting the importance of tailored monitoring strategies in this high-risk group.

Dermatology news Oncology

Integrated 40-Gene Expression Profile Enhances Prognostic Precision and Guides Adjuvant Radiation in High-Risk Cutaneous Squamous Cell Carcinoma

By MedXY 08/26/2026

The integrated 40-gene expression profile (i40-GEP) improves risk stratification in high-risk cutaneous squamous cell carcinoma, accurately predicting metastasis and local recurrence, and identifying patients who benefit most from adjuvant radiation therapy.

news Ophthalmology

Long-Term Efficacy and Visual Field Outcomes of Selective Laser Trabeculoplasty in Glaucoma Management

By MedXY 08/26/2026

This study evaluates long-term outcomes of selective laser trabeculoplasty (SLT) in controlling intraocular pressure and preventing visual field deterioration, identifying clinical factors influencing effectiveness and progression risk.

Critical Care Internal Medicine news

Post-ICU Frailty in Older Adults Following Septic Shock: Key Predictors and Clinical Implications

By MedXY 08/26/2026

This study identifies baseline frailty, organ dysfunction severity, and corticosteroid use as independent predictors of severe post-intensive care frailty in older septic shock survivors, highlighting critical factors for targeted post-ICU care.

Gastroenterology General Surgery news

Robotic Living Donor Hepatectomy: One-Year Prospective Insights into Donor Quality of Life and Psychosocial Outcomes

By MedXY 08/26/2026

A prospective study of 214 living liver donors undergoing robotic hepatectomy reveals excellent physical recovery and improved psychosocial wellbeing within one year post-donation, supporting the donor-centered benefits of this minimally invasive approach.

Allergy & Immunology news Ophthalmology

Immune-Mediated Disorders and Central Serous Chorioretinopathy: Clinical Insights from the MICRoN Report 21

By MedXY 08/26/2026

This study reveals that central serous chorioretinopathy (CSCR) in patients with immune-mediated disorders exhibits distinct clinical and imaging features, with immune-mediated status linked to poorer visual outcomes and higher recurrence, influenced by corticosteroid exposure.

Dermatology news

Reversing Epigenetic Aging in Psoriasis: The Impact of Tildrakizumab over 52 Weeks

By MedXY 08/26/2026

This study demonstrates that tildrakizumab, an IL-23 inhibitor, partially reverses accelerated epigenetic aging in psoriasis patients, highlighting a novel aspect of biologic therapy beyond skin inflammation control.

Hematology-Oncology news

Janus Kinase Inhibitors: Transforming Treatment Paradigms in Lymphomas and Immune-Mediated Complications

By MedXY 08/26/2026

Janus kinase inhibitors have emerged as pivotal agents in managing lymphoid malignancies and associated immune complications, offering new therapeutic avenues shaped by molecular insights into the JAK/STAT pathway.

Neurology news

Unveiling Metabolic Signatures: Glucose and Methionine PET Imaging in Disorders of Consciousness Post-Brain Injury

By MedXY 08/26/2026

This exploratory longitudinal study reveals that alongside decreased glucose metabolism, elevated brainstem methionine uptake correlates with consciousness improvement in brain-injured patients, highlighting novel metabolic biomarkers for prognosis in disorders of consciousness.

Anesthesiology news Otorhinolaryngology

Bridging the Communication Gap in Shared Airway Management: Insights from a Multicenter Survey of Anesthesiologists

By MedXY 08/26/2026

This survey reveals a paradox in shared airway management where anesthesiologists value otolaryngology input but often fail to utilize it due to systemic barriers, highlighting the need for integrated communication solutions and joint training.

Diabetes & Endocrinology news Ophthalmology

Teprotumumab Versus Intravenous Glucocorticoids in Thyroid Eye Disease: Insights from a Japanese MRI Study

By MedXY 08/26/2026

This study evaluates teprotumumab's effectiveness for thyroid eye disease in Japanese patients, revealing notable improvements in orbital inflammation and proptosis compared to intravenous glucocorticoid therapy with distinct MRI-based anatomical effects.

Neurology news

Alixorexton, a Novel Oral Orexin 2 Receptor Agonist, Shows Promising Safety and Efficacy in Narcolepsy Type 1: Insights from the Vibrance-1 Phase 2 Trial

By MedXY 08/26/2026

The Vibrance-1 phase 2 trial demonstrates that once-daily oral alixorexton significantly improves wakefulness and reduces cataplexy in narcolepsy type 1, with a favorable safety profile supporting phase 3 evaluation.

news Oncology Plastic Surgery

Oncoplastic Reconstruction Versus Reduction Mammoplasty in Macromastia: Safety, Satisfaction, and Aesthetic Outcomes Compared

By MedXY 08/26/2026

Oncoplastic breast reconstruction (OP) offers comparable safety and aesthetic results to bilateral breast reduction (BBR) while improving quality of life in women undergoing lumpectomy for macromastia.

Clinical Updates Dermatology news Oncology

AI-Assisted Line-Field Confocal Optical Coherence Tomography for Early Detection of Subclinical Basal Cell Carcinoma: Current Evidence and Clinical Prospects

By MedXY 08/26/2026

This review examines emerging evidence on AI-assisted LC-OCT as a noninvasive, accurate tool for detecting subclinical basal cell carcinoma in high-risk patients, highlighting diagnostic performance, subtype classification, and translational implications.

Diabetes & Endocrinology news

GLP1R R131Q Variant: A Genetic Key to Preserving β-Cell Function and Enhancing GLP-1RA Efficacy in Type 2 Diabetes

By MedXY 08/26/2026

The gain-of-function GLP1R R131Q variant slows β-cell decline and improves glycemic response to GLP-1 receptor agonists, highlighting its potential role in precision diabetes therapeutics.

Cardiology Critical Care news

Evaluating the Specificity of Capillary Leak Indices in Heart Failure: Implications for Clinical Practice

By MedXY 08/26/2026

This study demonstrates the lack of mechanistic specificity of clinical capillary leak indices in heart failure patients, underscoring their limitations as universal markers of endothelial permeability beyond acute inflammatory states.

Neurology news

Unveiling Non-Genetic Influences on Hereditary Ataxia: Insights from SCA6 and SCA27B Cohorts

By MedXY 08/26/2026

This study identifies key nongenetic factors impacting disease onset and severity in hereditary ataxias SCA6 and SCA27B, highlighting environmental exposures and demographics as important modifiers beyond genetic mutations.

Diabetes & Endocrinology General Surgery news

Enhancing Parathyroid Gland Preservation in Total Thyroidectomy: Efficacy of Near-Infrared Autofluorescence Probe (PTeye) Versus Visual Identification

By MedXY 08/26/2026

A randomized controlled trial demonstrates that PTeye-guided near-infrared autofluorescence significantly improves identification and preservation of parathyroid glands during total thyroidectomy, reducing transient hypoparathyroidism, especially in surgeries performed by junior surgeons.