二甲双胍联合孕激素用于子宫内膜肿瘤保留生育治疗：FELICIA 试验带来的启示
Posted innews OB/GYN & Women's Health Oncology

Adjunctive Metformin with Progestin in Fertility-Sparing Treatment of Endometrial Neoplasia: Insights from the FELICIA Trial

The FELICIA phase IIb trial found that adding metformin to progestin therapy for fertility-sparing treatment in endometrial neoplasia did not improve 3-year recurrence-free survival or remission rates, though some reproductive outcomes favored metformin. Safety was consistent with known profiles.
安大略省 ICU 推行全省网络家属满意度调查：一项质量改进实践的启示
Posted inCritical Care news Nursing & care

Implementing a Provincial Web-Based Family Satisfaction Survey in ICUs: Insights from Ontario’s Quality Improvement Initiative

A province-wide quality improvement initiative in Ontario implemented a web-based Family Satisfaction in ICU (FS-ICU) survey across adult level 3 ICUs, revealing high satisfaction scores yet highlighting challenges in participation and completion that inform future patient- and family-centered care improvements.
葡萄膜黑色素瘤的15-GEP/PRAME检测预后价值：有无确认性细胞病理学的比较
Posted innews Ophthalmology Pathology & Lab Medicine

Prognostic Value of 15-GEP/PRAME Assay With or Without Confirmatory Cytopathology in Uveal Melanoma: Insights From the Collaborative Ocular Oncology Group Study 2

This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is unavailable.
学术外科如何应对反DEI联邦政策：在多元、科研与公平之间寻求平衡
Posted inGeneral Surgery news Public Health

Navigating Anti-DEI Federal Policies in Academic Surgery: Strategies to Sustain Diversity, Research, and Equity

Federal executive orders restricting DEI initiatives pose significant challenges to academic surgery's workforce diversity, research integrity, and editorial freedom. Adaptive strategies integrating equity into existing quality and safety frameworks can preserve the mission under evolving legal constraints.
腎細胞癌の下大静脈血栓摘除術前に行う定位放射線焼灼療法：新たな第2相エビデンスの総括
Posted inClinical Updates news Oncology Radiology

Neoadjuvant Stereotactic Ablative Radiotherapy Prior to Inferior Vena Cava Thrombectomy in Renal Cell Carcinoma: A Synthesis of Emerging Phase 2 Evidence

This review synthesizes phase 2 trial data supporting neoadjuvant stereotactic ablative radiotherapy for RCC with IVC tumor thrombus, highlighting improved recurrence-free survival, acceptable safety, and biomarker insights that underscore its potential as a novel preoperative strategy.