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Caffeinated Coffee Linked to 39% Lower Risk of Atrial Fibrillation Recurrence: Results from the DECAF Randomized Trial

By MedXY 02/09/2026

The DECAF randomized trial challenges the traditional view of caffeine as a trigger for atrial fibrillation, demonstrating that coffee consumption significantly reduces arrhythmia recurrence after cardioversion compared to total abstinence.

Critical Care Nephrology news

Liberating the Kidney: Can a Conservative Dialysis Strategy Improve Recovery in AKI-D?

By MedXY 02/09/2026

The LIBERATE-D randomized trial suggests that a conservative, indication-driven dialysis strategy may enhance kidney recovery and reduce treatment burden in stable patients with dialysis-requiring acute kidney injury compared to conventional thrice-weekly dialysis.

General Surgery news Otorhinolaryngology

Thyroidectomy in Older Adults: Are Increased Relative Risks a Barrier to Surgical Safety?

By MedXY 02/08/2026

A systematic review and meta-analysis of over 400,000 patients reveals that while older adults face higher relative risks for nerve injury and hematoma following thyroidectomy, the absolute risk remains low, confirming the procedure's overall safety in the geriatric population.

Neurology news Radiology

Expanding the Thrombolysis Window: Tenecteplase Improves Outcomes in Late-Window Non-Large Vessel Occlusion Stroke

By MedXY 02/08/2026

The OPTION trial reveals that tenecteplase administered 4.5 to 24 hours post-stroke in patients with non-large vessel occlusion and salvageable tissue significantly improves functional recovery, although it carries a higher risk of symptomatic intracranial hemorrhage compared to standard care.

news Orthopedics

Combined ACL and ALL Reconstruction Significantly Reduces Graft Failure in High-Risk Young Patients: 5-Year RCT Evidence

By MedXY 02/08/2026

A 5-year randomized controlled trial reveals that combining ACL reconstruction with anterolateral ligament (ALL) reconstruction using hamstring autograft significantly outperforms bone-patellar tendon-bone autograft alone, reducing graft failure rates from 10.3% to 4.2% in young, active patients.

Cardiology Emergency Medicine news

Minutes Matter: How Modern Medicine is Winning the Race Against Heart Attacks

By MedXY 02/08/2026

An extensive study of 575,247 patients reveals significant improvements in hospital response times for heart attacks over the last decade, yet highlights critical gaps in care for women, elderly patients, and those admitted during off-hours.

Infectious Diseases news Public Health

RSV Frequently Precedes Influenza Peaks: Mapping the Temporal Sequence of the Post-Pandemic Triple-Threat in the United States

By MedXY 02/08/2026

A retrospective study of 148 state-level seasons reveals that RSV typically peaks three weeks before influenza, while COVID-19 lacks consistent seasonality, providing a critical framework for optimizing hospital resource allocation and vaccination timing.

news Pediatrics Respiratory

Pathophysiological Divergence in Preterm Infants: Early Lung Aeration and Gas Exchange as Predictors of Moderate-to-Severe Bronchopulmonary Dysplasia

By MedXY 02/08/2026

A multicentre prospective study reveals that infants developing moderate-to-severe BPD exhibit significant lung aeration and gas exchange deficits as early as day 10, with a critical pathophysiological peak at 26 days of life, regardless of the BPD definition used.

news Oncology Public Health

Mapping the European Cancer Landscape: A 1.7 Million Patient Study Reveals Survival Gaps and Comorbidity Patterns

By MedXY 02/07/2026

A large-scale federated study of 1.7 million European patients highlights significant variations in cancer survival and comorbidity profiles, emphasizing the role of real-world data and the OMOP-CDM framework in benchmarking oncological outcomes and identifying clinical prodromes.

news OB/GYN & Women’s Health Psychiatry

Prenatal Maternal Depression as a Critical Developmental Risk Factor: Large-Scale IPD Meta-Analysis of 76,514 Children

By MedXY 02/07/2026

This large-scale individual participant data meta-analysis of 76,514 children reveals that prenatal maternal depression is significantly associated with increased risks of ADHD, ASD, and behavioral symptoms, independent of pre-pregnancy depression and largely consistent across both male and female offspring.

Family Medicine & Nutrition Internal Medicine news Rheumatology

The Tart Cherry Revolution: A Deep Dive into the Science of Longevity, Recovery, and Restorative Sleep

By MedXY 02/07/2026

This article explores the multi-faceted health benefits of tart cherry juice, from its potent anti-inflammatory properties to its role in enhancing sleep and cardiovascular health, supported by the latest clinical research.

Neurology news Orthopedics

Restoring Movement: How Polylaminin is Revolutionizing Spinal Cord Injury Treatment

By MedXY 02/07/2026

Brazilian scientists have developed Polylaminin, a protein derived from human placenta that stimulates nerve regeneration. In early trials, six paralyzed patients regained the ability to walk, prompting official Phase I clinical trials to begin this year.

Internal Medicine news OB/GYN & Women’s Health

Antifibrotic Repurposing: How Finerenone Could Rejuvenate the Ovarian Niche and Restore Fertility in POI

By MedXY 02/07/2026

A breakthrough study in Science reveals that the antifibrotic drug finerenone restores fertility in premature ovarian insufficiency (POI) by reducing ovarian stromal fibrosis, enabling follicle development where hormone therapy previously failed.

Neurology news Pathology & Lab Medicine/Bệnh học

Biologically Informed p-tau217 Cutoffs: Refining Alzheimer’s Diagnosis Across Diverse Patient Profiles

By MedXY 02/06/2026

Standard single cutoffs for plasma p-tau217 are significantly confounded by kidney function, BMI, and anemia. A new study demonstrates that subgroup-specific or double-cutoff strategies markedly improve diagnostic accuracy and cost-effectiveness in detecting amyloid-β pathology.

Neurology news

Higher Serum Klotho Levels May Protect Cognitive Function Against Age-Related Brain Atrophy

By MedXY 02/06/2026

Research indicates that circulating levels of the longevity protein klotho can moderate the relationship between cerebral atrophy and cognitive performance in older adults, suggesting a biological mechanism for cognitive resilience even in the presence of structural brain changes.

news Pediatrics Public Health

Scaling Early Childhood Interventions: Blended Delivery Models in Primary Care Improve Child Development and Parenting

By MedXY 02/06/2026

A Jamaican randomized clinical trial demonstrates that a primary care-based parenting program using a blended delivery of home visits and phone calls significantly improves child developmental outcomes and parenting behaviors, offering a scalable model for public health systems.

Neurology news

Targeted Ipsilesional Training: A New Frontier for Enhancing Function in Severe Chronic Stroke

By MedXY 02/06/2026

A randomized clinical trial reveals that targeted training of the ipsilesional arm significantly improves motor performance in chronic stroke patients with severe contralesional impairment, offering a sustained pathway to enhance functional capacity in a long-neglected patient population.

news Psychiatry Rheumatology

Optimizing Value in Fibromyalgia Care: High-Dose Duloxetine and Pregabalin Outperform Amitriptyline in Lifetime Cost-Effectiveness Models

By MedXY 02/06/2026

A recent decision analytical model identifies duloxetine 120 mg as the most cost-effective treatment for moderate-to-severe fibromyalgia, providing superior clinical outcomes at a marginal cost increase compared to amitriptyline, particularly when societal impacts are considered.

Infectious Diseases news Public Health

2024-2025 COVID-19 Vaccines Provide 79% Protection Against Critical Illness Despite Viral Evolution

By MedXY 02/06/2026

A multicenter study reveals that 2024-2025 COVID-19 vaccines offer 40% protection against hospitalization and 79% against critical illness or death, maintaining efficacy against emerging JN.1 descendants like KP.3.1.1 and XEC.

news Psychiatry Public Health

The 400 Percent Transit Penalty: How Travel Barriers Systemically Restrict Methadone Access

By MedXY 02/06/2026

A geospatial analysis in Connecticut reveals that patients relying on public transit face travel times nearly four times longer than those with cars, with over 50% of areas lacking viable transit to methadone clinics, highlighting an urgent need for federal policy reform.