Beyond Information Delivery: Why Survivorship Care Plans Alone May Not Reduce Cardiovascular Risk in Cancer Survivors
Posted inCardiology news Oncology

Beyond Information Delivery: Why Survivorship Care Plans Alone May Not Reduce Cardiovascular Risk in Cancer Survivors

This article examines the CHIIP study, a randomized clinical trial evaluating whether survivorship care plan-based counseling improves cardiovascular risk factor control in childhood cancer survivors. Findings suggest that while documentation improved, counseling did not significantly outperform simple risk assessments.
Intensive Blood Pressure Targets Below 130/80 mmHg Benefit Patients Across the Cardiovascular-Kidney-Metabolic Syndrome Spectrum
Posted inCardiology Nephrology news

Intensive Blood Pressure Targets Below 130/80 mmHg Benefit Patients Across the Cardiovascular-Kidney-Metabolic Syndrome Spectrum

A post hoc analysis of the CRHCP trial demonstrates that intensive blood pressure control (<130/80 mmHg) significantly reduces major adverse **Confirming JSON Structure** I'm now fully focused on creating the JSON object. I've re-reviewed both schemas, and am following the most up-to-date and complete instructions. I'm double-checking the required fields, especially `thumbnail`, `lang`, and `multilang`, to ensure the final output is perfectly structured and valid. cardiovascular events across CKM syndrome stages 2 through 4, providing a favorable net clinical benefit despite an increased risk of hypotension.
Enhanced Care, Regardless of Format, Reduces Postpartum Depression in High-Risk Populations: Insights from the EMBRACE Trial
Posted innews OB/GYN & Women’s Health Psychiatry

Enhanced Care, Regardless of Format, Reduces Postpartum Depression in High-Risk Populations: Insights from the EMBRACE Trial

The EMBRACE randomized clinical trial demonstrates that both enhanced group and enhanced individual prenatal care significantly reduce postpartum depressive symptoms in low-income, diverse populations, suggesting that addressing social determinants of health is more critical than the specific delivery format of care.
Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes
Posted innews Psychiatry Public Health

Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes

A randomized clinical trial demonstrates that combining high-intensity circuit training (HICT) with sleep health (SH) counseling significantly outperforms mono-interventions in improving sleep efficiency, reducing wakefulness, and enhancing cardiometabolic markers in sedentary young women.
Letrozole, Abemaciclib, and Metformin Triplet Therapy Shows Robust Activity in ER-Positive Endometrioid Endometrial Cancer
Posted innews OB/GYN & Women’s Health Oncology

Letrozole, Abemaciclib, and Metformin Triplet Therapy Shows Robust Activity in ER-Positive Endometrioid Endometrial Cancer

A phase 2 trial demonstrates that combining letrozole, abemaciclib, and metformin achieves a 32% response rate and 60% clinical benefit rate in ER+ endometrioid endometrial cancer, with notable efficacy in CTNNB1-mutated tumors and an interesting pharmacokinetic interaction increasing metformin exposure.