Medxy AI

Understanding Key Stakeholders’ Perspectives Towards Artificial Intelligence in Home Care Work: An Evidence-Based Review

By MedXY 09/26/2026

This review synthesizes perspectives from key stakeholders on AI integration in home care, highlighting benefits, risks, and governance challenges to inform equitable, sustainable AI adoption.

Critical Care Internal Medicine news

Evolving Competence in Goals-of-Care Discussions Among Internal Medicine Physicians: Insights from a Qualitative Study Across Training Levels

By MedXY 09/26/2026

This qualitative study explores how internal medicine clinicians develop skills in discussing goals of care, revealing a progression from basic understanding to advanced, integrated communication approaches, and underscores the need for structured, stage-specific training.

Internal Medicine news Public Health

Tobacco Use Treatment: Key Points from the 2026 VA/DoD Clinical Practice Guideline

By MedXY 09/26/2026

A concise, clinician-friendly summary of the 2026 VA/DoD guideline for treating tobacco and nicotine use, focusing on evidence-based pharmacotherapy, counseling, and new recommendations for electronic and smokeless products.

Hematology-Oncology news Oncology

Decoding Large B Cell Lymphoma Heterogeneity: A Single-Cell Atlas Identifies Malignant Archetypes Linked to Patient Outcomes

By MedXY 09/26/2026

A comprehensive single-cell RNA sequencing study of large B cell lymphomas reveals five malignant B cell archetypes, with one subtype predictive of poor treatment response and survival, paving the way for precision therapy in LBCL.

Hematology-Oncology news Oncology

Personalizing Allogeneic Hematopoietic Cell Transplantation in Adult AML Using Measurable Residual Disease Testing

By MedXY 09/26/2026

Measurable residual disease (MRD) testing offers critical insights to tailor allogeneic hematopoietic cell transplantation in adults with acute myeloid leukemia, optimizing patient selection, conditioning intensity, and relapse surveillance to improve outcomes.

Hematology-Oncology news

Soluble BCMA as a Key Biomarker Defining Tumor Phenotypes and Prognosis in Newly Diagnosed Multiple Myeloma

By MedXY 09/26/2026

Soluble BCMA levels in newly diagnosed multiple myeloma patients reveal distinct tumor phenotypes and predict prognosis more strongly than tumor volume, enabling improved risk stratification and clinical decision-making.

Diabetes & Endocrinology news Respiratory

Harnessing Explainable Machine Learning for Personalized Obesity Hypoventilation Syndrome Risk Prediction in Bariatric Surgery Candidates

By MedXY 09/26/2026

An explainable machine learning model identifies bariatric surgery candidates at risk for obesity hypoventilation syndrome using seven accessible clinical variables, enhancing early diagnosis and perioperative risk management.

Infectious Diseases news Respiratory

Time-Normalized Anti-Aspergillus IgG Kinetics: A Novel Tool to Monitor Chronic Pulmonary Aspergillosis Progression

By MedXY 09/26/2026

Monitoring chronic pulmonary aspergillosis progression using time-normalized anti-Aspergillus IgG kinetics shows promise for early detection of disease worsening, supporting timely clinical reassessment alongside imaging and microbiology.

Infectious Diseases news Respiratory

Evolving Impact of Inhaled Antibiotics on Lung Function in Cystic Fibrosis During the CFTR-Modulator Era

By MedXY 09/26/2026

This analysis of U.S. CF Foundation registry data reveals that inhaled antibiotics confer lung function benefits primarily in chronic Pseudomonas aeruginosa infections, but their treatment benefit has declined with CFTR modulator use. Risks of secondary infections are higher in Pseudomonas-negative patients who do not benefit in lung function.

news Respiratory

Innovative Cryospray Therapy Shows Promise for Chronic Bronchitis in COPD Patients: Insights from the SPRAY-CB Trial

By MedXY 09/26/2026

Metered-dose liquid nitrogen cryospray significantly improves quality of life and reduces severe exacerbations in COPD patients with chronic bronchitis, with a favorable safety profile demonstrated in a recent sham-controlled trial.

Clinical Updates news Respiratory

Biologic Outcomes in Severe Asthma by Smoking Status: Insights from the SHARP European Registry

By MedXY 09/26/2026

SHARP registry data reveal that biologic therapies improve clinical outcomes equally in severe asthma patients irrespective of smoking status, challenging prevailing prescribing hesitancy and advocating inclusive treatment approaches.

news Oncology Ophthalmology

Optimizing Management of Conjunctival Melanocytic Lesions: A Sequential Multimodal Treatment Framework

By MedXY 09/26/2026

A retrospective cohort study demonstrates that a tailored, stepwise multimodal approach effectively controls conjunctival melanocytic lesions with reduced recurrence and metastasis risks, guided by lesion grade and clinical features.

news Otorhinolaryngology Pediatrics

Re-examining the Seasonal Pattern of Pediatric Epistaxis: A Decade-Long Mid-Atlantic Study

By MedXY 09/26/2026

This retrospective study found no significant seasonal variation in pediatric epistaxis referrals and management, challenging the common belief that nosebleeds peak in dry, winter months and suggesting year-round patient counseling.

news Oncology Otorhinolaryngology

Long-Term Airway Outcomes and Mortality Risks in Laryngeal Chondrosarcoma: Balancing Preservation and Oncological Control

By MedXY 09/26/2026

This retrospective study highlights the risk of airway complications and mortality in laryngeal chondrosarcoma patients managed with function-preserving surgery, emphasizing the need for vigilant surveillance and tailored treatments.

news Oncology Otorhinolaryngology

EHR-Integrated Synoptic Operative Reporting: Enhancing Documentation in Head and Neck Oncologic Surgery

By MedXY 09/26/2026

This study evaluates the development, implementation, and performance of EHR-integrated synoptic operative reporting templates in head and neck cancer surgery, highlighting improved documentation quality and variable adherence.

Gastroenterology news Oncology

Nationwide Dutch Study Reveals Limited Prior Endoscopic Surveillance in Barrett’s Esophagus-Related Dysplasia and Cancer Diagnosis

By MedXY 09/26/2026

In a large Dutch cohort, 90% of patients with Barrett’s esophagus-related dysplasia or cancer had no prior endoscopic surveillance, highlighting a critical gap in early detection and the need for evidence-based screening strategies.

Gastroenterology Internal Medicine news

Distinct Gut Microbiome Signatures Predict Short-term Hospitalisation Risk in Cirrhosis: Insights from a Global Metagenomic Study

By MedXY 09/26/2026

This multinational study reveals that specific gut microbiome profiles significantly correlate with 90-day hospitalisation risk in cirrhosis, enhancing prognostic accuracy beyond clinical features alone.

Gastroenterology news Oncology

Decoding Steatohepatitic Hepatocellular Carcinoma: Multi-Omics Insights and Emerging Diagnostic-Therapeutic Pathways

By MedXY 09/26/2026

This study integrates multi-omics data to characterize steatohepatitic hepatocellular carcinoma (SH-HCC), establishing robust diagnostic models and identifying FABP4 as a promising therapeutic target, with implications for personalized management strategies.

Diabetes & Endocrinology Nephrology news

Worsening Time in Range as a Predictor of Microvascular Complications in Type 1 Diabetes: Insights from a 5-Year Real-World Study

By MedXY 09/26/2026

A 5-year real-world cohort study reveals that declines in CGM-derived time in range correlate with increased microvascular complications in type 1 diabetes, offering prognostic value beyond HbA1c.

Diabetes & Endocrinology news Pediatrics

Pubertal Delay Associated with Paternally Derived 15q11.2-q13 Duplication Syndrome and MKRN3 Overexpression: A Case Series

By MedXY 09/26/2026

This report discusses four patients with paternally inherited 15q11.2-q13 duplications linked to MKRN3 overexpression, presenting with delayed puberty and varying degrees of hypogonadism.