Substituting Water for Artificially Sweetened Beverages Fails to Improve Glycemic Control in Type 2 Diabetes: Results from the SODAS Trial
Posted inDiabetes & Endocrinology Internal Medicine news

Substituting Water for Artificially Sweetened Beverages Fails to Improve Glycemic Control in Type 2 Diabetes: Results from the SODAS Trial

The Study of Drinks with Artificial Sweeteners (SODAS) randomized trial reveals that replacing habitual artificially sweetened beverages with water does not improve HbA1c levels in patients with type 2 diabetes, with the water group surprisingly showing higher HbA1c levels than the beverage group.
Oral Semaglutide Slows eGFR Decline in Patients with Type 2 Diabetes and High Cardiovascular Risk: Insights from the SOUL Trial
Posted inCardiology Diabetes & Endocrinology Nephrology news

Oral Semaglutide Slows eGFR Decline in Patients with Type 2 Diabetes and High Cardiovascular Risk: Insights from the SOUL Trial

The SOUL trial demonstrates that oral semaglutide significantly slows the annual decline of estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes and cardiovascular disease, despite not meeting the primary composite kidney endpoint in a population with preserved baseline renal function.
Tau Pathology Acts as a Switch: How Soluble Amyloid Drives Early Metabolic and Neuropsychiatric Symptoms in Alzheimer’s Disease
Posted inNeurology news Psychiatry

Tau Pathology Acts as a Switch: How Soluble Amyloid Drives Early Metabolic and Neuropsychiatric Symptoms in Alzheimer’s Disease

Recent clinical evidence reveals that soluble amyloid-beta oligomers, rather than traditional plaques, drive glucose dysregulation and depression in early Alzheimer’s disease. Crucially, these associations are modulated by tau pathology, suggesting that tau staging is essential for identifying metabolic and psychiatric vulnerability in the AD spectrum.
Nurse-Led Education Program Effectively Reduces Treatment Delay in Patients with Diabetic High-Risk Foot: A Randomized Controlled Trial
Posted inDiabetes & Endocrinology news Nursing & care

Nurse-Led Education Program Effectively Reduces Treatment Delay in Patients with Diabetic High-Risk Foot: A Randomized Controlled Trial

This randomized controlled trial demonstrates that a structured nurse-led education intervention significantly improves foot care knowledge and self-efficacy while reducing both the intention and actual behavior of delaying treatment in patients with diabetic high-risk foot.
Parental Firearm Injury Linked to Significant Surge in Pediatric Psychiatric Disorders and Mental Health Service Utilization
Posted innews Pediatrics Psychiatry

Parental Firearm Injury Linked to Significant Surge in Pediatric Psychiatric Disorders and Mental Health Service Utilization

A large-scale longitudinal study reveals that children whose parents suffer firearm injuries face a significant increase in psychiatric diagnoses, particularly trauma-related disorders. These findings highlight the profound secondary psychological impact of firearm violence on families and the urgent need for trauma-informed pediatric care.
Beyond Concentration: The MUCQ Score Redefines Chronic Bronchitis Identification
Posted innews Pathology & Lab Medicine Respiratory

Beyond Concentration: The MUCQ Score Redefines Chronic Bronchitis Identification

Researchers introduce the Mucin Quantitative Score (MUCQ), a novel metric combining mucin concentration and composition. Validated in the SPIROMICS cohort, MUCQ outperforms traditional total mucin measurements in identifying chronic bronchitis, offering a more precise tool for diagnosing and tracking muco-obstructive lung diseases.