Personalized Automatic Management of Tracheal Cuff Pressure and Subglottic Secretion Drainage to Prevent Pneumonia in Critically Ill Intubated Patients: The MICROINHALO Multicenter Randomized Controlled Trial

Personalized Automatic Management of Tracheal Cuff Pressure and Subglottic Secretion Drainage to Prevent Pneumonia in Critically Ill Intubated Patients: The MICROINHALO Multicenter Randomized Controlled Trial

MICROINHALO found that automatic cuff pressure control plus subglottic secretion drainage did not reduce tracheal colonization, but it was linked to fewer ventilator-associated pneumonia cases in critically ill intubated patients.
Negative End-Expiratory Transpulmonary Pressure, Lung Collapse, and Non-Focal ARDS Drive Tidal Recruitment During Pressure Support Ventilation

Negative End-Expiratory Transpulmonary Pressure, Lung Collapse, and Non-Focal ARDS Drive Tidal Recruitment During Pressure Support Ventilation

In spontaneously breathing ARDS patients on pressure support ventilation, tidal recruitment/derecruitment was strongly linked to more negative end-expiratory transpulmonary pressure, greater collapse, and non-focal infiltrates, while EIT-guided PEEP reduced recruitment/derecruitment compared with a low PEEP/FiO2 table approach.