Medxy AI

Evaluating Beta Cell Function in Preclinical Type 1 Diabetes Using CGM-Derived Disposition Index

By MedXY 10/14/2026

A novel CGM-derived disposition index reliably estimates beta cell function in individuals with islet autoimmunity without insulin therapy, predicting glycemic deterioration one year later.

news OB/GYN & Women's Health

Menstrual Cycle Influence on Exercise Performance: The Role of Cramp Severity and Psychological Factors in Active Women

By MedXY 10/14/2026

This study explores how menstrual cycle phases and cramp severity affect exercise capacity and psychological responses in physically active eumenorrheic women, revealing no direct performance differences across phases but highlighting the impact of cramps and mood.

news Orthopedics Plastic Surgery

Innovative Optical Tracking Enhances Upper Extremity Joint Assessment in Burn Patients

By MedXY 10/14/2026

A novel marker-based optical motion capture system demonstrates excellent reliability and validity in measuring upper limb joint range of motion in burn injury patients, offering a promising objective alternative to conventional goniometers.

Dentistry news

Comparative 1-Year Evaluation of 3D-Printed Resin Crowns Versus Monolithic Zirconia Crowns for Posterior Prostheses

By MedXY 10/14/2026

This 1-year randomized controlled trial compares the clinical performance, wear, and fracture incidence of 3D-printed resin crowns and zirconia crowns in posterior tooth restorations, revealing acceptable adaptation but higher wear and fracture risk in resin crowns.

Internal Medicine news Public Health

Facilitated vs Self-Guided Advance Care Planning in Black and White Older Adults: Insights from the EQUAL ACP Randomized Trial

By MedXY 10/14/2026

The EQUAL ACP trial compared facilitated and self-guided advance care planning in Black and White older adults with serious illnesses, revealing no significant difference in overall ACP completion but greater facilitated approach efficacy among Black participants.

Cardiology news Pediatrics

How Physical Activity Shapes Youth Heart Health: Insights from Device-Measured Studies

By MedXY 10/14/2026

This article explores recent meta-analytic evidence on how device-measured physical activity and sedentary behavior relate to cardiometabolic risk markers in children and adolescents, revealing nuanced benefits of moderate-to-vigorous exercise for heart health but limited impact from sedentary time.

news Rheumatology

What’s New in EULAR’s 2026 SOPs: How Rheumatology Guidelines Will Be Built from Now On

By MedXY 10/14/2026

The 2026 EULAR update modernizes how recommendations and points-to-consider for rheumatic and musculoskeletal diseases are developed — formalizing patient partnership, living guidance, robust evidence synthesis, cost-awareness and transparent consensus processes.

General Surgery Nephrology news

Obesity and Kidney Transplantation: Weighing Risks and Outcomes from a Swiss Single-Center Study

By MedXY 10/14/2026

This Swiss retrospective study reveals that while obesity in kidney transplant recipients increases early surgical complications and delayed graft function, it does not affect long-term patient or graft survival, suggesting obesity alone should not exclude candidates from transplantation.

Dermatology Hematology-Oncology news

Refining Prognostication in Advanced Mycosis Fungoides and Sézary Syndrome: The Role of the Cutaneous Lymphoma International Prognostic Index (CLIPI)

By MedXY 10/14/2026

The Cutaneous Lymphoma International Prognostic Index (CLIPI) enhances risk stratification and predicts progression and treatment response beyond conventional staging in advanced mycosis fungoides and Sézary syndrome.

news Plastic Surgery

Evaluating the Safety of Standardized Tranexamic Acid Dosage in Facelift Surgery: Insights from a Large Retrospective Cohort

By MedXY 10/14/2026

This study demonstrates that standardized dosing of tranexamic acid, combined with local anesthetic in rhytidectomy, does not increase ischemic or systemic complications, supporting its safe use in facelift procedures.

news Psychiatry

Enhanced Psychosocial Functioning in Schizophrenia: Clinical Trial Evidence for Modified Psychodynamic Psychotherapy in Germany

By MedXY 10/14/2026

A German randomized controlled trial demonstrates that Modified Psychodynamic Psychotherapy for Schizophrenia (MPP-S) combined with standard care significantly improves psychosocial functioning over two to three years compared to standard care alone.

Cardiology Clinical Updates Emergency Medicine news

Derivation and Validation of Claims-Based Operational Definitions for Cardiogenic Shock: Enhancing Diagnostic Accuracy and Epidemiologic Surveillance

By MedXY 10/14/2026

This review synthesizes evidence on the derivation and validation of a claims-based algorithm for identifying cardiogenic shock (CS), demonstrating its high diagnostic performance and enabling robust large-scale epidemiologic and long-term outcome research.

Cardiology Emergency Medicine news

Outcomes and Diagnostic Spectrum of Paramedic-Suspected STEMI: Insights from a Statewide Registry

By MedXY 10/14/2026

Paramedic-suspected STEMI identified a heterogeneous, high-acuity population where 60% had confirmed STEMI; outcomes vary by final diagnosis, underscoring the need for rapid reperfusion with early diagnostic refinement.

Clinical Updates Emergency Medicine news

Where Women Veterans Seek Emergency Care: Patterns and Predictors of VA and Community Emergency Department Use

By MedXY 10/14/2026

This review synthesizes evidence on women Veterans' emergency care utilization, comparing VA and Community ED use. It highlights demographic and clinical predictors influencing care settings and underscores the need for tailored coordination to address diverse health needs.

Hematology-Oncology news

KT-253: A Novel MDM2 Degrader Targeting Malignant Stem Cells in Myelofibrosis

By MedXY 10/14/2026

KT-253, a selective MDM2 protein degrader, shows potent elimination of malignant myelofibrosis stem/progenitor cells by enhancing p53 pathway activation, outperforming current MDM2 inhibitors and offering a promising therapeutic advance.

Clinical Updates Critical Care news Respiratory

Modulation of Respiratory Drive by Ondansetron in Acute Respiratory Distress Syndrome: Emerging Evidence and Clinical Implications

By MedXY 10/14/2026

Ondansetron, a 5-HT3 antagonist, reduces respiratory drive in ARDS patients on mechanical ventilation by attenuating pulmonary C-fiber mediated stimulation, potentially lessening lung injury and improving oxygenation.

news Oncology Ophthalmology

Corneal Epithelial Changes Induced by CDK4/6 Inhibitors in HR+ Breast Cancer: Clinical Insights and Implications

By MedXY 10/14/2026

CDK4/6 inhibitor therapy in hormone receptor-positive breast cancer is linked to increased corneal epithelial alterations, including punctate epitheliopathy and vortex keratopathy, independent of aromatase inhibitor effects or tear film dysfunction.

AI news Otorhinolaryngology Pediatrics

AI-Assisted Video Monitoring Revolutionizes Care for Tracheostomy-Dependent Infants: A Proof-of-Concept Evaluation

By MedXY 10/14/2026

This study demonstrates promising accuracy of a patient-personalized AI system in detecting tracheostomy tube status and infant distress via video monitoring, highlighting potential for enhanced, continuous surveillance in high-risk infants requiring tracheostomy care.

news OB/GYN & Women's Health Oncology

Evaluating Perioperative Safety and Recovery: Robot-Assisted Versus Open Radical Hysterectomy in Early-Stage Cervical Cancer

By MedXY 10/14/2026

A secondary analysis of the RACC trial reveals robot-assisted radical hysterectomy reduces intraoperative complications but shows similar postoperative morbidity and modest quality-of-life benefits compared with open surgery in early-stage cervical cancer.

news OB/GYN & Women's Health

The Retrograde Migration of Foreign Bodies inside the Female Genital Tract: A Step-by-Step Hysteroscopic Approach

By MedXY 10/14/2026

Two cases of retrograde migration of foreign bodies in the female genital tract were successfully managed with a minimally invasive hysteroscopic technique involving electrosurgical radial incision and Foley catheter dilation, emphasizing safety and effective removal.