Medxy AI

Clinical Impact of Digoxin Withdrawal in Heart Failure: Insights from the DECISION Trial

By MedXY 10/24/2026

The DECISION trial demonstrated that discontinuation of low-dose digoxin in heart failure patients optimized on guideline therapy leads to increased heart failure events and clinical deterioration, supporting cautious withdrawal decisions.

news Orthopedics Pediatrics

Psychological Readiness as a Predictor of Successful Return to Sports in Adolescents After Patellar Stabilization Surgery

By MedXY 10/24/2026

This retrospective study reveals that psychological readiness, measured by ACL-RSI scores, significantly predicts return to sport in adolescent patients after patellar stabilization surgery, overshadowing demographic and surgical factors.

news Orthopedics Pediatrics Rehabilitation Medicine

Aquatic Plyometrics: A Breakthrough in Managing Adolescent Patellofemoral Pain Syndrome

By MedXY 10/24/2026

Aquatic plyometric exercises significantly improve pain, muscle strength, and quality of life in adolescents with patellofemoral pain syndrome, offering a safe and effective rehabilitation option.

Internal Medicine news Superintelligence

AI-Derived Panoramic Radiograph Score Links Oral Health to Major Systemic Diseases

By MedXY 10/24/2026

An AI-generated panoramic dental imaging score correlates independently with diabetes, hypertension, ischemic heart disease, osteoporosis, and hyperlipidemia, supporting integrated medical-dental care.

news Orthopedics Rheumatology

Garetosmab: A Promising Disease-Modifying Antibody for Fibrodysplasia Ossificans Progressiva

By MedXY 10/24/2026

This phase 3 trial shows garetosmab significantly reduces new heterotopic bone lesions and is generally well tolerated in adults with fibrodysplasia ossificans progressiva (FOP), an ultra-rare and disabling genetic disorder.

news Pediatrics

Oral Health for Adolescents: Key Recommendations from the 2026 AAP Clinical Report

By MedXY 10/24/2026

A concise, practice-focused summary of the 2026 AAP clinical report on adolescent oral health—what pediatric clinicians should screen for, prevent, and refer.

news Rheumatology

Early Lipid Metabolic Alterations in Synovial Fibroblasts: A Window into Rheumatoid Arthritis Pathogenesis

By MedXY 10/24/2026

Enhanced lipolysis in synovial fibroblasts marks early pathogenic changes in individuals at risk for rheumatoid arthritis, indicating metabolic shifts precede clinical disease onset.

Gastroenterology news Public Health

Bridging the Gap: Global Disparities in Liver Transplantation and Disease Burden (2000-2023)

By MedXY 10/24/2026

This article analyzes global liver transplantation disparities relative to cirrhosis and chronic liver disease burden, revealing unequal access dominated by high-income countries and highlighting the role of health system development in transplantation capacity.

Allergy & Immunology Dermatology news

Litifilimab Shows Promising Efficacy and Safety in Treating Cutaneous Lupus Erythematosus: Insights from the AMETHYST Phase 2 Trial

By MedXY 10/24/2026

The AMETHYST Phase 2 trial demonstrated that litifilimab significantly improves skin symptoms in cutaneous lupus erythematosus with a favorable safety profile, marking a potential new targeted treatment for this challenging condition.

General Surgery news Plastic Surgery

Ultrasound as a Reliable Tool for Localizing Lymphovenous Anastomosis Sites in Lymphedema Surgery: Diagnostic Accuracy and Clinical Implications

By MedXY 10/24/2026

Ultrasound demonstrates high accuracy and reproducibility in preoperative localization of lymphovenous anastomosis sites, outperforming existing methods and offering a robust tool for lymphedema surgery planning.

Critical Care Hematology-Oncology news

Heightened Risk of ICU-Acquired Infections in Hematological and Immunosuppressed Cancer Patients: Insights from a Large Brazilian Cohort

By MedXY 10/24/2026

A large nationwide cohort study reveals that patients with hematological malignancies and other immunosuppressive conditions have significantly higher risks of ICU-acquired infections, while those with solid tumors do not show increased incidence compared to non-immunosuppressed patients.

Internal Medicine news Respiratory

Unraveling Racial Disparities in Respiratory Tract Infection Diagnoses and Antibiotic Prescribing Patterns

By MedXY 10/24/2026

Racial disparities in respiratory tract infection diagnoses partially explain lower antibiotic prescribing rates in non-White patients, highlighting the need for equitable clinical assessment and antibiotic stewardship.

Hematology-Oncology news

Targeting Immunoglobulin Constant Domains: A Novel T-Cell Receptor-Based Immunotherapy for Multiple Myeloma

By MedXY 10/24/2026

This study identifies immunoglobulin heavy chain constant domain-derived peptides as promising TCR therapy targets in multiple myeloma, demonstrating selective cytotoxicity and potential to preserve humoral immunity.

news Respiratory

Immunomodulatory Effects of Clarithromycin in Community-Acquired Pneumonia: Insights from the ACCESS Trial’s Inflammatory Proteome Analysis

By MedXY 10/24/2026

This study reveals that clarithromycin modulates inflammatory cytokines in community-acquired pneumonia, identifying distinct immune endotypes that may guide personalized immunomodulatory therapy.

news Ophthalmology

Charlson Comorbidity Index as a Predictor of Visual Outcomes in Retinal Vein Occlusion-Related Macular Edema: Insights from a Decade-Long Cohort Study

By MedXY 10/24/2026

Higher Charlson Comorbidity Index scores correlate with worse 1-year visual acuity outcomes in macular edema secondary to retinal vein occlusion, highlighting the impact of systemic health on ocular prognosis.

news Otorhinolaryngology Plastic Surgery

Understanding Patient-Initiated Communication in Septorhinoplasty: Prevalence, Themes, and Predictors

By MedXY 10/24/2026

This article analyzes perioperative patient-initiated communication in septorhinoplasty, highlighting common concerns and identifying factors linked to increased contact with clinical teams, providing insights to improve patient care quality.

Cardiology news OB/GYN & Women's Health

Pregnancy Outcomes in Women with Preexisting Cardiomyopathy: Insights from a UK Prospective Cohort Study

By MedXY 10/24/2026

This UK prospective study assesses pregnancy outcomes in women with preexisting cardiomyopathy, revealing generally favorable maternal and neonatal results with low cardiac complication rates and no maternal deaths.

Internal Medicine news OB/GYN & Women's Health

Bridging the Gap: Addressing Low Breast Cancer Screening Rates Among Resident Physicians in Academic Primary Care

By MedXY 10/24/2026

Resident physicians demonstrate lower breast cancer screening rates compared to faculty, even in well-supported academic practices. Adjusting for patient and physician factors narrows, but does not eliminate, this gap, underscoring the need to redesign residency training to improve preventive care delivery.

Hematology-Oncology news

Cases of High-Titer Inhibitor Formation After AAV Gene Therapy for Hemophilia A

By MedXY 10/24/2026

Two hemophilia A patients developed persistent high-titer FVIII inhibitors following AAV-mediated gene therapy with a bioengineered FVIII transgene despite prior extensive FVIII exposure.

進行性肺線維症における定量的CT：INBUILD試験サブスタディから得られた知見

news Respiratory

Quantitative Computed Tomography in Progressive Pulmonary Fibrosis: Insights from the INBUILD Trial Sub-Study

By MedXY 10/24/2026

Quantitative CT imaging offers valuable prognostic information and helps assess treatment response in patients with progressive pulmonary fibrosis, supporting better clinical trial outcomes and therapeutic decisions.