Medxy AI

Unlocking the Potential of Novel Biomarkers for Acute Kidney Injury in the Critically Ill: A Comprehensive Evidence Mapping

By MedXY 09/18/2026

This article reviews over 1100 studies on novel biomarkers for acute kidney injury (AKI) in critically ill patients, highlighting their predictive, diagnostic, and management roles while identifying gaps for future clinical implementation.

Emergency Medicine news

Evaluating the Impact of Relative Value Unit-Based Compensation on Emergency Physician Performance and Operational Outcomes

By MedXY 09/18/2026

A national study examining the shift from hourly to RVU-based pay for emergency physicians found no significant changes in productivity, billing intensity, or key operational metrics, suggesting compensation models may not strongly influence clinical or service outcomes.

Internal Medicine news Nursing & care

Facilitators and Barriers of Using Smart Bedside Station Systems Among Hospitalized Patients: A Qualitative Study Based on UTAUT

By MedXY 09/18/2026

This study explores factors that promote or hinder hospitalized patients' use of Smart Bedside Station systems, revealing that nursing support and useful video education encourage use, while cognitive and workflow challenges limit sustained engagement.

Clinical Updates news Oncology

Optimizing Palliative Care for Effective Hospice Transitions in Cancer Patients: Insights from Multicenter Qualitative and Quantitative Evidence

By MedXY 09/18/2026

This review synthesizes evidence identifying critical programmatic factors, relational dynamics, and interventions enhancing hospice transitions in cancer palliative care, emphasizing collaborative oncology-palliative care relationships and integrated supportive strategies.

Internal Medicine Nephrology news

KDIGO 2026 on Anemia in CKD: Key Recommendations and Practical Guidance for Clinicians

By MedXY 09/18/2026

KDIGO 2026 updates anemia care in CKD: evidence-based thresholds for iron therapy, preference for IV iron on hemodialysis, ESA-first approach over HIF-PHIs, individualized Hb initiation, and an ESA maintenance upper Hb target <11.5 g/dL.

Hematology-Oncology news

Optimizing Autologous Stem Cell Backup Mobilization with GCSF and Plerixafor in Sickle Cell Disease: Implications for Gene Therapy

By MedXY 09/18/2026

A retrospective study demonstrates the safety and efficacy of GCSF and plerixafor for CD34+ stem cell mobilization as autologous backup in sickle cell patients undergoing alternate donor HSCT, with insights relevant for gene therapy.

Hematology-Oncology news

Efficacy and Safety of All-Oral Ixazomib, Pomalidomide, and Dexamethasone in Triple-Class Exposed Multiple Myeloma: Insights from a Phase II Study

By MedXY 09/18/2026

This phase II study evaluates the all-oral ixazomib-pomalidomide-dexamethasone regimen in triple-class exposed relapsed/refractory multiple myeloma patients, demonstrating promising efficacy and manageable safety in an elderly and high-risk cohort.

Hematology-Oncology news

Asciminib as a Robust Treatment Option for BCR::ABL1 T315I-Mutated Chronic Myeloid Leukemia: Final Phase 1 Trial Outcomes

By MedXY 09/18/2026

Long-term phase 1 data confirm asciminib's efficacy and safety in treating CML-CP patients harboring the resistant BCR::ABL1 T315I mutation, with sustained major molecular responses and manageable adverse events over nearly six years.

Hematology-Oncology news

Harnessing Type-I Interferon-Activated NK Cells: A Novel Immunotherapeutic Approach to Polycythemia Vera

By MedXY 09/18/2026

This article explores how type-I interferon activates NK cells to control polycythemia vera progression, revealing insights into immune modulation and therapeutic potential in myeloproliferative neoplasms.

Allergy & Immunology news Respiratory

Rademikibart and Eosinophil Counts in Moderate-to-Severe Asthma: Insights from a Phase 2b Randomized Trial

By MedXY 09/18/2026

This article reviews exploratory analyses from a phase 2b trial examining eosinophil count changes in adults with uncontrolled moderate-to-severe asthma treated with the IL-4Rα inhibitor rademikibart, indicating a low risk of treatment-emergent hypereosinophilia.

Infectious Diseases news Respiratory

Decoding Pseudomonas aeruginosa Subtypes: Implications for Clinical Variability in Bronchiectasis

By MedXY 09/18/2026

Distinct Pseudomonas aeruginosa abundance and interaction patterns in bronchiectasis patients reveal heterogeneity influencing clinical outcomes and treatment responses, offering new avenues for personalized management.

$One-Year Outcomes of WaveLight Plus InnovEyes Ray-Tracing-Guided LASIK: Precision Refractive Correction for Myopia and Myopic Astigmatism$

news Ophthalmology

One-Year Outcomes of WaveLight Plus InnovEyes Ray-Tracing-Guided LASIK: Precision Refractive Correction for Myopia and Myopic Astigmatism

By MedXY 09/18/2026

This prospective study demonstrates that WaveLight Plus InnovEyes ray-tracing-guided LASIK achieves excellent safety, efficacy, and astigmatic correction precision in treating myopia and myopic astigmatism over one year.

news Otorhinolaryngology Pathology & Lab Medicine

Evaluating the Utility of Routine Tonsil Pathology in a Safety-Net Hospital: Low Yield of Unexpected Malignancies Supports Risk-Stratified Approach

By MedXY 09/18/2026

A retrospective cohort study at a safety-net hospital found that routine pathological examination of tonsillectomy specimens rarely reveals unexpected malignancies, supporting targeted pathology based on clinical assessment.

Gastroenterology news Oncology

Rising Early-Onset Colorectal Cancer and Persistent Racial Disparities Despite Increased Colonoscopy Use

By MedXY 09/18/2026

From 2017 to 2023, colonoscopy use increased notably in adults under 50. Yet, early-onset colorectal cancer rates and racial disparities, particularly among Black and Hispanic populations, worsened, highlighting that screening alone does not resolve these inequities.

Gastroenterology General Surgery news

Integrative Muscle-Adipose Score (IMAS): Enhancing Sex-Sensitive Prognostication After Liver Transplantation

By MedXY 09/18/2026

The Integrative Muscle-Adipose Score (IMAS) combines muscle and fat measures into a sex-specific tool that accurately predicts long-term survival and postoperative complications in liver transplant recipients, outperforming existing models.

Gastroenterology Neurology news

Harnessing Kynurenic Acid and the Gut-Brain Axis to Improve Stroke Recovery

By MedXY 09/18/2026

Kynurenic acid (KYNA) reduction in the gut correlates with worse poststroke outcomes. Supplementation activates a gut-brain neural circuit via GPR35 and the vagus nerve, promoting neuroprotection and functional recovery after ischemic stroke.

Diabetes & Endocrinology Neurology news

SGLT2 Inhibitors Enhance Recovery After Endovascular Thrombectomy in Diabetic Stroke Patients: A Multicenter Retrospective Study

By MedXY 09/18/2026

SGLT2 inhibitors administered after endovascular thrombectomy in diabetic stroke patients significantly improve 3-month functional outcomes, suggesting a promising adjunctive therapy for poststroke diabetes management.

Diabetes & Endocrinology news Ophthalmology

Fenofibrate Use and Reduced Risk of Sight-Threatening Diabetic Retinopathy in Type 2 Diabetes: Insights from UK Real-World Data

By MedXY 09/18/2026

Fenofibrate use in type 2 diabetes patients is associated with a significant reduction in the risk of sight-threatening diabetic retinopathy compared to statins, based on UK primary care data over 12 years.

Cardiology news

Geographic Variability in Outcomes of IVUS-Guided Versus Angiography-Guided PCI: Insights from a Meta-Analysis of Randomized Trials

By MedXY 09/18/2026

This meta-analysis reveals significant geographic differences in the benefits of intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI), with East Asian populations showing marked reductions in cardiac death and adverse events compared to non-Asian groups.

Cardiology news

Unveiling a Cryptic MYBPC3 Variant Amplifying Missplicing in Hypertrophic Cardiomyopathy

By MedXY 09/18/2026

A deep-intronic MYBPC3 variant magnifies natural mRNA missplicing events, causing hypertrophic cardiomyopathy and explaining previously genotype-negative cases through an ancient founder effect and novel splice regulation.