Beyond the Incessant Ovulation Hypothesis: How Menopausal Status and Birth Cohort Reshape Ovarian Cancer Risk
Posted innews OB/GYN & Women’s Health Oncology

Beyond the Incessant Ovulation Hypothesis: How Menopausal Status and Birth Cohort Reshape Ovarian Cancer Risk

A massive cohort study of 2.2 million women reveals that ovarian cancer risk factors vary significantly by menopausal status and birth year. While early menarche and low parity remain universal risks, the protective benefits of breastfeeding and oral contraceptives appear specific to premenopausal women.
Video Remote Interpreting for Deaf Patients: Bridging Communication Gaps or Just a Digital Band-Aid?
Posted inFamily Medicine & Nutrition news Public Health

Video Remote Interpreting for Deaf Patients: Bridging Communication Gaps or Just a Digital Band-Aid?

This randomized clinical trial evaluates Video Remote Interpreting (VRI) for Deaf patients, finding that while it empowers patients to express themselves, it does not significantly improve their overall understanding of physicians, suggesting that technology alone cannot solve complex clinical communication barriers.
Scalable Telephone-Based Behavioral and Mindfulness Interventions Effectively Reduce Long-Term Loneliness in At-Risk Older Adults: Insights from the HEAL-HOA Trial
Posted innews Psychiatry Public Health

Scalable Telephone-Based Behavioral and Mindfulness Interventions Effectively Reduce Long-Term Loneliness in At-Risk Older Adults: Insights from the HEAL-HOA Trial

The HEAL-HOA randomized clinical trial demonstrates that lay counselor-delivered telephone interventions using behavioral activation and mindfulness significantly and sustainably reduce loneliness and improve well-being among vulnerable, digitally excluded older adults over a 12-month period.
Standardized DOAC Interruption Protocols Result in Low Residual Levels, but Apixaban and Renal Impairment Merit Closer Monitoring
Posted inCardiology General Surgery news

Standardized DOAC Interruption Protocols Result in Low Residual Levels, but Apixaban and Renal Impairment Merit Closer Monitoring

The DALI cohort study reveals that while current DOAC interruption protocols are generally effective, 13.1% of apixaban users maintain levels ≥30 ng/mL before surgery. However, these residual levels did not correlate with increased surgical blood loss, suggesting other factors drive perioperative bleeding.
Psychosocial Interventions for Dual-Diagnosis Schizophrenia: A Critical Appraisal of Efficacy and the Urgent Need for Innovation
Posted innews Psychiatry

Psychosocial Interventions for Dual-Diagnosis Schizophrenia: A Critical Appraisal of Efficacy and the Urgent Need for Innovation

A comprehensive meta-analysis in JAMA Psychiatry reveals that current psychosocial interventions for schizophrenia and co-occurring substance use disorders offer negligible impact on symptoms and no significant effect on substance use reduction, with the notable exception of nicotine cessation strategies.