Medxy AI

Prognostic Value of Early ST2 and REG3α Measurements in Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide

By MedXY 10/23/2026

Early increases in serum ST2 and REG3α within the first week after haploidentical stem cell transplantation with post-transplant cyclophosphamide predict transplant outcomes, highlighting their potential as prognostic biomarkers.

Allergy & Immunology news Rheumatology

Switching from Mepolizumab to Benralizumab in EGPA: A Promising Alternative for Persistent Respiratory Symptoms

By MedXY 10/23/2026

In EGPA patients unresponsive to mepolizumab, switching to benralizumab improves lung function, reduces glucocorticoid use, and shows a favorable safety profile, suggesting its potential as an effective alternative treatment.

news Ophthalmology

Impact of 24-Hour Blood Pressure Variability on Retinal Nerve Fiber Layer Progression in Primary Open-Angle Glaucoma

By MedXY 10/23/2026

Lower systemic blood pressure, especially minimum values measured over 24 hours, is associated with accelerated retinal nerve fiber layer loss in primary open-angle glaucoma, highlighting the prognostic value of ambulatory BP monitoring.

news Otorhinolaryngology

Advancing Ear Disease Diagnosis: Optical Coherence Tomography Enables Quantitative, Point-of-Care Tympanic Membrane Imaging

By MedXY 10/23/2026

Optical coherence tomography (OCT) otoscopy delivers rapid, quantitative imaging of the tympanic membrane, distinguishing normal and diseased ears, improving diagnostic accuracy, and allowing longitudinal monitoring of middle ear pathologies in point-of-care settings.

General Surgery Hematology-Oncology news

Impact of Cholecystitis Treatment on Continuation of Cancer Therapy: Insights from a Decade-long Institutional Study

By MedXY 10/23/2026

This study evaluates how treatment for cholecystitis affects the timely resumption of cancer therapy, highlighting that half of cancer patients return to therapy within six weeks, with hematologic malignancies and drainage procedures linked to delays or treatment cessation.

脊髄長軸性硬膜外CSF貯留を伴う自発性頭蓋内低血圧の管理に関する専門家コンセンサス：2026年Delphi研究の主要提言

Neurology news

Expert Consensus on Managing Spontaneous Intracranial Hypotension with Spinal Longitudinal Epidural CSF Collections: Key Recommendations from a 2026 Delphi Study

By MedXY 10/23/2026

An international Delphi panel offers practical, evidence-informed recommendations for managing spontaneous intracranial hypotension with spinal longitudinal epidural CSF collections, clarifying peri-epidural blood patch practice, imaging choices, definitions of remission, and persistent-leak strategies.

Diabetes & Endocrinology Neurology news

Hippocampal Structural Alterations and White Matter Changes in Congenital Adrenal Hyperplasia: Insights into Sex-Specific Brain Vulnerabilities

By MedXY 10/23/2026

This study reveals significant hippocampal subfield volume reductions and white matter impairments in patients with congenital adrenal hyperplasia, highlighting sex-specific differences that could influence cognitive outcomes and treatment approaches.

Cardiology news

Aldosterone Levels and Mineralocorticoid Receptor Antagonists in Heart Failure: Implications for Personalized Therapy

By MedXY 10/23/2026

This article explores how baseline aldosterone concentrations influence the efficacy and outcomes of mineralocorticoid receptor antagonists (MRAs) in heart failure patients, highlighting the need for tailored therapeutic approaches.

Neurology news Orthopedics

Exploring Reticulospinal Tract Plasticity: Effects of Short-Term Isometric Resistance Training on Neural Adaptations

By MedXY 10/23/2026

This study evaluated whether 4 weeks of unilateral isometric elbow flexion resistance training induce adaptations in human reticulospinal tract function, finding no significant changes despite strength gains, thus informing neurorehabilitation strategies.

news Orthopedics Public Health

Bridging the Gap: Physiotherapists’ Views on Direct Access in Austria’s Referral-Based Care System

By MedXY 10/23/2026

This qualitative study explores Austrian physiotherapists' perspectives on direct access, revealing existing informal practice, confidence levels, organizational barriers, and training needs critical for policy reforms.

Dentistry news Oncology

Optimizing Management of Medication-Related Osteonecrosis of the Jaw: Insights from a Single-Center Retrospective Cohort

By MedXY 10/23/2026

This study evaluates outcomes of medication-related osteonecrosis of the jaw (MRONJ) treatments in 222 patients, highlighting the superiority of surgical interventions over conservative therapy, especially in osteoporosis-associated cases.

术中联用多巴酚丁胺与去甲肾上腺素可显著降低脓毒性休克术后急性肾损伤：来自多中心随机试验的证据

Critical Care Nephrology news

Intraoperative Dobutamine Plus Norepinephrine Significantly Reduces Postoperative Acute Kidney Injury in Septic Shock: Insights from a Multicenter Randomized Trial

By MedXY 10/23/2026

A randomized clinical trial demonstrates that adding intraoperative dobutamine to norepinephrine during surgical source control for septic shock significantly decreases postoperative acute kidney injury incidence and severity.

新生児医療的男子割礼は自閉スペクトラム症のリスクを高めるか：前向きコホート研究が示した結論

news Pediatrics Public Health

Neonatal Medical Male Circumcision and Autism Spectrum Disorder: Evaluating the Evidence from a Prospective Cohort Study

By MedXY 10/23/2026

A large prospective cohort study found no evidence linking neonatal medical male circumcision with increased risk of autism spectrum disorder or autism-related traits in children, providing reassurance for families and clinicians.

Internal Medicine Nephrology news

Ultrasound-Derived Renal Parenchymal Volume Indexed to BMI: A Novel Predictor of One-Year Kidney Graft Function

By MedXY 10/23/2026

Indexing donor kidney parenchymal volume by recipient BMI via routine ultrasound strongly predicts one-year kidney graft function, offering a practical surrogate for graft-recipient size matching.

Dermatology news Pediatrics

Telehealth Behavioral Intervention for Melanoma Prevention in Children of Survivors: Insights from a Randomized Clinical Trial

By MedXY 10/23/2026

A telehealth intervention improved sun-protective behaviors among children of melanoma survivors but did not sustain reductions in sunburn rates compared to education alone, highlighting the challenge of long-term melanoma prevention in high-risk youth.

news Plastic Surgery Superintelligence

Navigating the Future: Medical and Legal Implications of Artificial Intelligence in Plastic Surgery

By MedXY 10/23/2026

This article explores the expanding role of artificial intelligence in plastic surgery, detailing medical benefits, legal risks, and strategies for risk mitigation to protect patients and practitioners.

Critical Care Emergency Medicine news

Predicting Outcomes in Acutely Intoxicated ICU Patients: Integrating Toxicity Scores and Laboratory Data

By MedXY 10/23/2026

This study develops and evaluates prognostic models combining clinical and toxicity information to predict complicated outcomes in ICU patients with acute intoxication, demonstrating the added value of laboratory data over toxicity scores alone.

Internal Medicine news Psychiatry

Integrating Pharmacists into Opioid Use Disorder Care: Feasibility and Acceptability in Primary Care Settings

By MedXY 10/23/2026

A nonrandomized clinical trial demonstrates that incorporating pharmacists into primary care teams to manage opioid use disorder enhances feasibility, reduces care barriers, and maintains high acceptability among providers and patients.

KIT 抑制剂治疗晚期全身性肥大细胞增多症的结局预测：来自基因与实验室动态监测的启示

Hematology-Oncology news

Predicting Outcomes in Advanced Systemic Mastocytosis with KIT Inhibitors: Insights from Genetic and Laboratory Monitoring

By MedXY 10/23/2026

This article reviews how genetic profiling and dynamic laboratory markers predict clinical outcomes in advanced systemic mastocytosis treated with KIT inhibitors avapritinib and midostaurin, facilitating optimized treatment strategies.

自动监测气管导管套囊压力可降低儿科ICU呼吸机相关性肺炎：一项高质量随机对照试验的新证据

Critical Care news Pediatrics

Continuous Automatic Endotracheal Cuff Pressure Monitoring Reduces Ventilator-Associated Pneumonia in Pediatric ICU: New Evidence from a Robust RCT

By MedXY 10/23/2026

Continuous automatic cuff pressure monitoring significantly lowers ventilator-associated pneumonia incidence in critically ill children by ensuring better pressure control, offering an effective preventive strategy in pediatric intensive care.