葡萄膜黑色素瘤的15-GEP/PRAME检测预后价值:有无确认性细胞病理学的比较

Prognostic Value of 15-GEP/PRAME Assay With or Without Confirmatory Cytopathology in Uveal Melanoma: Insights From the Collaborative Ocular Oncology Group Study 2

This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is unavailable.
矯正レンズ支出の動向:費用・障壁・政策含意をめぐるエビデンスレビュー

Trends in Spending on Corrective Lenses: An Evidence-Based Review on Expenditures, Barriers, and Policy Implications

Corrective lens spending affects nearly 20% of the US population, with half paying fully out-of-pocket, highlighting substantial financial burdens and access barriers. Evidence from clinical trials and epidemiologic studies underscores cost-effectiveness of interventions and the need for policy reform in vision care coverage.
Prevalence of Diabetic Retinopathy and Cardiovascular Risk Factors Among Diverse Hispanic/Latino Adults: Insights from the HCHS/SOL and SOL Ojos Studies

Prevalence of Diabetic Retinopathy and Cardiovascular Risk Factors Among Diverse Hispanic/Latino Adults: Insights from the HCHS/SOL and SOL Ojos Studies

More than one-third of Hispanic/Latino adults with diabetes exhibit diabetic retinopathy (DR), with significant variability across backgrounds. Hypertension notably associates with DR and vision-threatening DR, highlighting the need for targeted cardiovascular risk management and tailored screening.
Impact of Donor Diabetes Severity on 1-Year Outcomes After Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study

Impact of Donor Diabetes Severity on 1-Year Outcomes After Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study

A thorough secondary analysis of a randomized clinical trial reveals no significant association between cornea donor diabetes severity and graft success, endothelial cell loss, or morphometric parameters at 1 year post-DMEK, supporting the use of diabetic donor corneas without additional preoperative risk stratification.