Neurology – Medxy AI

High-Frequency 10-kHz Spinal Cord Stimulation: Advancing Pain Relief and Sensory Recovery in Painful Diabetic Neuropathy

By MedXY 09/12/2026

A multicenter RCT demonstrates that 10-kHz spinal cord stimulation significantly improves pain relief, sensory function, and nerve fiber density in painful diabetic neuropathy, suggesting potential disease-modifying effects.

Cardiology Neurology news

Global Trends in the Burden of Ischemic Stroke Attributable to Diabetes Versus Atrial Fibrillation

By MedXY 09/11/2026

This study analyzes global trends comparing ischemic stroke burdens linked to diabetes and atrial fibrillation, revealing a rising impact of diabetes-related stroke and highlighting the need for targeted interventions.

Clinical Updates Neurology news

Smoking, Exhaled Carbon Monoxide, and Parkinson’s Disease Risk: Epidemiological Insights and Mechanistic Perspectives

By MedXY 09/11/2026

This review explores evidence linking smoking and exhaled carbon monoxide levels to reduced Parkinson's disease risk, emphasizing a potential protective role of carbon monoxide, supported by recent large-scale cohort data and biological insights into PD pathophysiology.

Neurology news

Common MC1R Variants and Parkinson Disease Progression

By MedXY 09/11/2026

This study links MC1R loss-of-function variants to faster motor decline and phenoconversion in Parkinson's disease, suggesting their value for prognosis and clinical trial design in European descent patients.

Clinical Updates Neurology news

Tenecteplase Efficacy in Distal Cerebral Artery Occlusions: Insights From the Secondary Analysis of the TASTE Randomized Clinical Trial

By MedXY 09/09/2026

Secondary analysis of the TASTE trial reveals tenecteplase confers superior functional outcomes versus alteplase in patients with distal middle cerebral artery occlusions, supporting its use in more peripheral ischemic stroke territories.

Cardiology Neurology news

Ischaemic Stroke Risk in Atrial Flutter Versus Atrial Fibrillation: Insights from a Finnish Nationwide Registry Study

By MedXY 09/09/2026

This Finnish nationwide study demonstrates that patients with atrial flutter have a substantially lower risk of ischaemic stroke compared to those with atrial fibrillation, highlighting important differences in thromboembolic risk profiles between these arrhythmias.

Neurology news Radiology

Early Detection of Cerebral Small Vessel Disease: Diffusion MRI Reveals a Decade-Long Preclinical Phase Before White Matter Hyperintensities

By MedXY 09/08/2026

Diffusion MRI detects microstructural brain changes up to 16 years before white matter hyperintensities appear, offering a valuable early window for cerebral small vessel disease intervention and improved risk stratification.

Clinical Updates Neurology news

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke: A Comprehensive Review

By MedXY 09/08/2026

Accumulating evidence underscores how adverse social determinants of health (SDOH) from early adulthood heighten the risk of early-onset stroke, with dose-dependent effects and disparities by race and sex.

Clinical Updates Neurology news

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: Insights from a Prospective Multicenter Cohort Study in China

By MedXY 09/08/2026

Pregnancy significantly reduces antiseizure medication concentrations, with lamotrigine showing the greatest decline. Polytherapy and body weight modulate these changes, underscoring the importance of individualized therapeutic drug monitoring during gestation.

Critical Care Neurology news

Immigration Status and Acute Stroke ICU Care: Insights from Ontario’s Population-Based Study

By MedXY 09/08/2026

This retrospective cohort study explores how immigration status influences ICU admission rates and length of stay among ischemic stroke patients in Ontario, revealing longer ICU stays for immigrants despite similar admission rates compared to long-term residents.

Cardiology Neurology news

Ticagrelor-Aspirin Dual Therapy After Thrombolysis in Moderate Ischemic Stroke: Insights from Infarct Patterns in the TAPIS Trial

By MedXY 09/06/2026

TAPIS subgroup analysis reveals that ticagrelor-aspirin combined with thrombolysis may improve outcomes in moderate ischemic stroke patients with multiple acute infarcts, without increasing hemorrhage risk, suggesting infarct pattern as a potential guide for early antiplatelet therapy.

Clinical Updates Neurology news

Cilostazol Therapy in Intracerebral Hemorrhage: Enhancing Dural Lymphatic Function for Neuroprotection

By MedXY 09/06/2026

Cilostazol promotes dural lymphatic remodeling and hematoma clearance post-ICH without increasing bleeding risk, representing a promising therapeutic strategy to improve neurological outcomes.

Neurology news Radiology

CSF Biomarkers as Indicators of Disease Severity in Probable Cerebral Amyloid Angiopathy: Insights Beyond MRI

By MedXY 09/06/2026

This study demonstrates that cerebrospinal fluid beta-amyloid peptides correlate with MRI markers of disease severity in probable cerebral amyloid angiopathy, suggesting CSF biomarkers provide a direct measure of vascular amyloid burden, independent of Alzheimer-like pathology.

Cardiology Neurology news

Unraveling Central Autonomic Network Disruptions Underlying Cardiorespiratory Dysfunction in Temporal Lobe Epilepsy

By MedXY 09/06/2026

This study reveals that central autonomic network alterations in temporal lobe epilepsy patients contribute to interictal cardiorespiratory dysfunction, potentially increasing SUDEP risk, and highlights connectivity changes post-surgery impacting autonomic function.

Neurology news Otorhinolaryngology

Prednisone Use Post-Acoustic Neuroma Surgery Does Not Prevent Delayed Facial Nerve Palsy: A Retrospective Analysis

By MedXY 09/05/2026

A retrospective study found that postoperative prednisone tapering does not reduce delayed facial nerve palsy incidence following acoustic neuroma resection and carries a 10% risk of steroid-related side effects.

Neurology news

BCKDK: Unlocking a New Hypoxia-Sensitive Target to Mitigate Cerebral Ischemic Injury

By MedXY 09/05/2026

This article details how BCKDK, a hypoxia-induced kinase, disrupts branched-chain amino acid metabolism to worsen neuronal injury in cerebral ischemia, highlighting its potential as a novel therapeutic target.

Neurology news

Unraveling the Link Between Alzheimer’s Pathology, Sleep Disturbances, and Cognitive Decline in Late-Onset Unexplained Epilepsy

By MedXY 09/05/2026

Elevated plasma p-tau217 correlates with cognitive impairment and altered sleep microarchitecture in older adults with late-onset unexplained epilepsy, highlighting potential pathways linking neurodegeneration, epilepsy severity, and sleep disruptions.

Neurology news

Unraveling Alzheimer’s Disease Progression in Down Syndrome via Blood Proteome Dynamics

By MedXY 09/05/2026

Longitudinal analysis of blood proteins reveals distinctive trajectories and associations with cognitive decline in adults with Down syndrome, shedding light on Alzheimer's disease pathophysiology in this high-risk group.

Neurology news

Evaluating Tirofiban Plus Aspirin in Branch Atheromatous Disease Stroke: Insights from the STRATEGY Trial

By MedXY 09/05/2026

The STRATEGY trial assessed whether combining tirofiban with aspirin improves outcomes in branch atheromatous disease (BAD)-related stroke but found no significant benefit over aspirin alone in preventing neurological deterioration or recurrent stroke.