Longitudinal Voice Changes in Transmasculine Adolescents and Young Adults Undergoing Testosterone Therapy: Insights from a Prospective Cohort Study

Longitudinal Voice Changes in Transmasculine Adolescents and Young Adults Undergoing Testosterone Therapy: Insights from a Prospective Cohort Study

This study prospectively characterizes voice changes over 12 months in transmasculine adolescents and young adults receiving testosterone therapy, demonstrating significant lowering of pitch, improved voice congruence, and reduced anxiety, thereby informing gender-affirming voice care.
Impact of Maternal Third-Trimester TRAb Levels on Neonatal Thyroid Function and Early Childhood Neurodevelopment: Insights from a Bidirectional Cohort Study

Impact of Maternal Third-Trimester TRAb Levels on Neonatal Thyroid Function and Early Childhood Neurodevelopment: Insights from a Bidirectional Cohort Study

Elevated maternal third-trimester TRAb levels in Graves' disease are linked to neonatal thyroid dysfunction and impaired neurodevelopment at 24 months, independent of neonatal thyroid status, highlighting the need for prenatal monitoring and intervention strategies.
Relationship between Participant-Reported Outcomes, Residual Beta Cell Function, and Metabolic Parameters in Youth with Newly Diagnosed Type 1 Diabetes

Relationship between Participant-Reported Outcomes, Residual Beta Cell Function, and Metabolic Parameters in Youth with Newly Diagnosed Type 1 Diabetes

This study examines how participant-reported outcomes relate to residual beta cell function and metabolic control in youth newly diagnosed with type 1 diabetes, highlighting modest associations with glucose management but weaker links to beta cell preservation.