Relationship between Participant-Reported Outcomes, Residual Beta Cell Function, and Metabolic Parameters in Youth with Newly Diagnosed Type 1 Diabetes
Posted inDiabetes & Endocrinology news Pediatrics

Relationship between Participant-Reported Outcomes, Residual Beta Cell Function, and Metabolic Parameters in Youth with Newly Diagnosed Type 1 Diabetes

This study examines how participant-reported outcomes relate to residual beta cell function and metabolic control in youth newly diagnosed with type 1 diabetes, highlighting modest associations with glucose management but weaker links to beta cell preservation.
Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide
Posted inDiabetes & Endocrinology news

Exploring Low-Dose Antithymocyte Globulin Therapy in Type 1 Diabetes: Real-World Insights Using Modified Quantitative Response of C-Peptide

This article examines real-world data on low-dose antithymocyte globulin in type 1 diabetes, assessing beta-cell function via a novel C-peptide modified quantitative response (mQR). Findings suggest feasibility, safety, and potential clinical benefit in preserving endogenous insulin secretion.
Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence
Posted inClinical Updates Diabetes & Endocrinology news Public Health

Human versus Analogue Insulin for Youth with Type 1 Diabetes in Low-Resource Settings: Insights from the HumAn-1 Trial and Complementary Evidence

The HumAn-1 trial found no significant differences between insulin glargine and human isophane insulin in hypoglycemia risk or glucose control in young T1D patients in low-resource settings, underscoring accessibility over insulin type in these contexts.
High-Intensity Interval Exercise in Type 1 Diabetes: Stronger Protection Against Exercise-Related Glycaemic Decline in the Postabsorptive Than Postprandial State
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High-Intensity Interval Exercise in Type 1 Diabetes: Stronger Protection Against Exercise-Related Glycaemic Decline in the Postabsorptive Than Postprandial State

This clinical update reviews a new randomized crossover trial and prior literature showing that high-intensity interval exercise can attenuate glucose decline and late hypoglycaemia in adults with type 1 diabetes, particularly when performed in the postabsorptive state.