Dairy-Enriched High-Protein Breakfast Enhances Circadian Gene Expression and Glycemic Control in Type 2 Diabetes

Dairy-Enriched High-Protein Breakfast Enhances Circadian Gene Expression and Glycemic Control in Type 2 Diabetes

A randomized crossover trial demonstrates that a dairy-enriched diet with high-protein breakfast and early daytime carbohydrate restriction significantly upregulates circadian clock genes (BMAL1, REV-ERBα, CRY1), improves glycemic metrics including fasting glucose and time in range, and reduces appetite in individuals with type 2 diabetes.
Breaking the Silos: How the PACE-It Model Improves Outcomes in Multimorbid Patients through Integrated Social and Clinical Care

Breaking the Silos: How the PACE-It Model Improves Outcomes in Multimorbid Patients through Integrated Social and Clinical Care

The PACE-It pilot program demonstrates that integrating health and social care via multidisciplinary teams and technology significantly improves glycemic control, lipid management, and patient activation for individuals with complex needs, offering a scalable model for bridging systemic silos in primary care.
Bridging the Health-Social Gap: The PACE-It Model Shows Promise for Complex Multimorbidity Management

Bridging the Health-Social Gap: The PACE-It Model Shows Promise for Complex Multimorbidity Management

A pilot randomized controlled trial demonstrates that the PACE-It program, an integrated multidisciplinary team utilizing technology-assisted communication, significantly improves glycemic control, lipid management, and patient activation in individuals with complex diabetes and psychosocial needs.
Video Remote Interpreting for Deaf Patients: Bridging Communication Gaps or Just a Digital Band-Aid?

Video Remote Interpreting for Deaf Patients: Bridging Communication Gaps or Just a Digital Band-Aid?

This randomized clinical trial evaluates Video Remote Interpreting (VRI) for Deaf patients, finding that while it empowers patients to express themselves, it does not significantly improve their overall understanding of physicians, suggesting that technology alone cannot solve complex clinical communication barriers.
Behavioral Science-Integrated EHR Prompts Significantly Increase Deprescribing Rates for Older Adults: A Randomized Clinical Trial

Behavioral Science-Integrated EHR Prompts Significantly Increase Deprescribing Rates for Older Adults: A Randomized Clinical Trial

This randomized clinical trial demonstrates that EHR-based behavioral interventions, such as precommitment and boostering prompts, significantly improve deprescribing rates for potentially inappropriate medications in older adults, providing a scalable strategy to mitigate polypharmacy risks in primary care.
Biopsychosocial Self-Management Superior to Standard Care for Reducing Disability in Acute Back Pain: Insights from the PACBACK Trial

Biopsychosocial Self-Management Superior to Standard Care for Reducing Disability in Acute Back Pain: Insights from the PACBACK Trial

The PACBACK randomized trial reveals that clinician-supported biopsychosocial self-management significantly reduces one-year disability in patients with acute low back pain at high risk of chronicity, whereas spinal manipulation alone offers no significant advantage over standard medical care.
Smartphone-Based Pulmonary Rehabilitation Bridging the Gap in Chronic Respiratory Care: A Randomized Controlled and Feasibility Study

Smartphone-Based Pulmonary Rehabilitation Bridging the Gap in Chronic Respiratory Care: A Randomized Controlled and Feasibility Study

A randomized trial demonstrates that a smartphone app-based pulmonary rehabilitation program significantly improves quality of life and physical activity in patients with chronic respiratory diseases, offering a scalable alternative to traditional center-based care despite challenges in patient adherence.
Calcium Supplementation During Pregnancy for Preventing Hypertensive Disorders: Current Evidence and Clinical Implications

Calcium Supplementation During Pregnancy for Preventing Hypertensive Disorders: Current Evidence and Clinical Implications

This review synthesizes recent randomized controlled trials and meta-analyses on calcium supplementation during pregnancy, evaluating its effectiveness in preventing hypertensive disorders such as pre-eclampsia and related maternal and neonatal outcomes.