risk stratification

Validated Risk Stratification for RYR2-Mediated Catecholaminergic Polymorphic Ventricular Tachycardia on Beta-Blocker Therapy

By MedXY 09/06/2026

This article reviews a validated clinical risk model predicting arrhythmic events in patients with RYR2-mediated CPVT receiving beta-blockers, facilitating personalized management to reduce life-threatening arrhythmias.

news Otorhinolaryngology Pediatrics

Enhancing Early Detection of Neonatal Hearing Loss: A Machine Learning Risk Stratification Approach

By MedXY 08/31/2026

This article discusses a novel machine learning-based tool, especially XGBoost, to predict hearing loss risk in high-risk neonates using clinical factors for targeted early intervention.

Gastroenterology Internal Medicine news

From Pressure Metrics to Personalized Prognosis: Transforming Risk Assessment in Advanced Chronic Liver Disease

By MedXY 08/31/2026

A shift from static portal pressure thresholds to dynamic, non-invasive risk prediction models offers improved prognostic accuracy for decompensation in advanced chronic liver disease, enabling personalized patient management and better clinical outcomes.

Cardiology news Respiratory

Advanced Right Ventricular Phenotyping Enhances Risk Stratification in Pulmonary Arterial Hypertension Follow-Up

By MedXY 08/28/2026

Echocardiography-derived right ventricular phenotypes improve prognostic accuracy beyond standard risk tools in pulmonary arterial hypertension patients at first follow-up, refining survival predictions and guiding management strategies.

Dermatology news Oncology

Integrated 40-Gene Expression Profile Enhances Prognostic Precision and Guides Adjuvant Radiation in High-Risk Cutaneous Squamous Cell Carcinoma

By MedXY 08/26/2026

The integrated 40-gene expression profile (i40-GEP) improves risk stratification in high-risk cutaneous squamous cell carcinoma, accurately predicting metastasis and local recurrence, and identifying patients who benefit most from adjuvant radiation therapy.

Allergy & Immunology Cardiology news

Unveiling Hidden Immune Signatures in Cardiovascular Disease Through Single-Cell Multi-Omics

By MedXY 08/21/2026

Single-cell multi-omics profiling reveals novel immune signatures linked to coronary artery disease and cardiovascular outcomes, independent of traditional inflammatory markers, offering new avenues for risk stratification and personalized therapy.

Dermatology Hematology-Oncology news

Risk Stratification Models in Blood or Marrow Transplant Recipients for Predicting Cutaneous Malignant Neoplasms

By MedXY 08/16/2026

Blood or marrow transplant recipients face an increased risk of skin cancers. This study develops validated risk models to identify high-risk patients for basal cell carcinoma, squamous cell carcinoma, and melanoma to optimize surveillance strategies.

Gastroenterology news

Comparative Effectiveness of Shear Wave Elastography and VCTE in MASLD Risk Stratification: Insights from FIB-4-Based Two-Step Algorithms

By MedXY 08/15/2026

Shear wave elastography (SWE) shows comparable accuracy to vibration-controlled transient elastography (VCTE) for stratifying liver-related event risk in MASLD patients using FIB-4-based two-step algorithms.

Cardiology news

Dynamic Metabolic Profiling in Chronic Heart Failure: Insights from Serial NMR Biomarkers and Risk Prediction

By MedXY 08/13/2026

Serial nuclear magnetic resonance metabolic profiling reveals distinct lipid and inflammatory markers predictive of adverse outcomes in chronic heart failure, supporting its role in improving risk stratification.

Dermatology news Oncology

Dynamic Risk Stratification of Melanocytic Lesions with Peripheral Globules: Insights from a Longitudinal Cohort Study

By MedXY 08/11/2026

Longitudinal monitoring reveals that persistence and growth dynamics of peripheral globules in melanocytic lesions predict melanoma risk more accurately than static features alone, informing tailored surveillance strategies.

news Ophthalmology

PRISM Framework: A Comprehensive Staging System for Open-Angle Glaucoma and Risk Stratification

By MedXY 08/11/2026

This article presents the PRISM model, a unified glaucoma classification integrating risk profiling, structural imaging, functional testing, and disease progression to enhance diagnosis and inform treatment strategies for open-angle glaucoma.

$Combining Tissue Hypoperfusion Markers with Vasopressor Dose Enhances Mortality Risk Stratification in Refractory Septic Shock$

Critical Care Infectious Diseases news

Combining Tissue Hypoperfusion Markers with Vasopressor Dose Enhances Mortality Risk Stratification in Refractory Septic Shock

By MedXY 07/21/2026

Persistent tissue hypoperfusion alongside vasopressor dosing improves early risk stratification in refractory septic shock, identifying patients with markedly increased 28-day mortality beyond vasopressor dose alone, as shown in a secondary analysis of the ANDROMEDA-SHOCK-2 trial.

Diabetes & Endocrinology news

Refining HbA1c Thresholds for Accurate Type 1 Diabetes Progression Risk in Islet Autoantibody-Positive Adults

By MedXY 07/12/2026

Adjusting HbA1c thresholds for age improves risk prediction of type 1 diabetes progression in adults positive for islet autoantibodies, enhancing prevention strategies.

Hematology-Oncology news

A Comprehensive Prognostic Model for Predicting Leukemia-Free Survival Following Allogeneic Hematopoietic Cell Transplantation in Acute Leukemia

By MedXY 07/07/2026

This article discusses a novel holistic H-score prognostic model integrating patient, disease, and treatment factors to predict leukemia-free survival after allogeneic transplantation in acute leukemia, enhancing risk stratification beyond existing models.

General Surgery news Otorhinolaryngology

Predictive Role of the Modified Frailty Index in Short-Term Complications After Total Thyroidectomy

By MedXY 07/05/2026

Higher Modified Frailty Index scores correlate with increased postoperative complications and emergency visits following total thyroidectomy, underscoring the value of frailty assessment in surgical risk stratification.

Cardiology news Radiology

Harnessing Cardiac CT Radiomics of Epicardial Fat for Early Heart Failure Prediction

By MedXY 07/04/2026

Radiomic analysis of epicardial adipose tissue from routine cardiac CT scans enables robust, noninvasive early prediction of heart failure risk, enhancing conventional models and supporting precision prevention strategies.

Cardiology news Respiratory

Decoding Pulmonary Arterial Hypertension in Congenital Heart Disease: Latent Class Analysis Uncovers Distinct Risk Phenotypes and Treatment Insights

By MedXY 06/25/2026

Latent class analysis of 889 adult PAH-CHD patients identified unique phenogroups with distinct survival outcomes and treatment responses, offering refined risk stratification and guiding personalized therapy.

news Ophthalmology Public Health

Most Open-Angle Glaucoma Suspects Convert at Less Than 6% Per Year After Year 1, Supporting Risk-Stratified Follow-Up

By MedXY 06/06/2026

A large US claims-based cohort suggests that most open-angle glaucoma suspects have modest annual conversion risk after the first year, and that age- and treatment-informed surveillance intervals may help tailor follow-up intensity.

news Psychiatry Public Health

Polygenic Scores Often Rival Recurrent CNVs for Psychiatric Risk Stratification, but Both Add Clinical Insight

By MedXY 05/31/2026

A large Danish genetic study suggests recurrent CNVs and polygenic scores provide complementary psychiatric risk information, with polygenic scores often identifying more at-risk individuals and potentially modifying CNV-associated risk.

Critical Care Dermatology news

Hospital-Acquired DRESS and Clinical Severity Strongly Predict ICU Admission in a 39-Centre Paris Cohort

By MedXY 05/27/2026

In this multicentre cohort of 207 hospitalized adults with DRESS, 17% required ICU care. Hospital-acquired DRESS and greater clinical severity independently predicted ICU admission, while ICU mortality reached 20%.