Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention

Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention

A large UK Biobank cohort study of 121,017 postmenopausal women reveals that earlier menopause significantly increases risks of multimorbidity progression, with women experiencing premature menopause facing 32% higher risk of developing first chronic disease and 22% higher risk of progressing to multimorbidity compared to those with menopause after age 50.
Is Female Sex a Truly Independent Risk Factor for Stroke in Atrial Fibrillation? Insights from a Large European Cohort

Is Female Sex a Truly Independent Risk Factor for Stroke in Atrial Fibrillation? Insights from a Large European Cohort

A large European cohort study reveals that while women with atrial fibrillation are less likely to receive anticoagulants and show higher crude thromboembolism rates, female sex is not an independent risk factor after adjusting for comorbidities. The CHA2DS2-VASc score remains superior for clinical reclassification.