stroke – Medxy AI

Retinal OCTA as a Window into Cerebral Small Vessel Disease and Cognitive Decline Post-Stroke

By MedXY 09/20/2026

This longitudinal study shows that retinal microvascular changes measured by OCTA correspond with cerebral small vessel disease progression and cognitive decline in mild ischemic stroke patients, highlighting OCTA's potential as a noninvasive biomarker for brain vascular health.

Neurology news

Early Recanalization in Distal and Medium Vessel Occlusion Strokes: Tenecteplase vs Alteplase

By MedXY 09/15/2026

In patients with distal and medium vessel occlusion strokes, tenecteplase achieves higher early recanalization rates and reduces early infarct growth compared to alteplase, supporting its preferential use in this clinical setting.

Neurology news

Evaluating Tirofiban Plus Aspirin in Branch Atheromatous Disease Stroke: Insights from the STRATEGY Trial

By MedXY 09/05/2026

The STRATEGY trial assessed whether combining tirofiban with aspirin improves outcomes in branch atheromatous disease (BAD)-related stroke but found no significant benefit over aspirin alone in preventing neurological deterioration or recurrent stroke.

Cardiology Neurology news

Higher Stroke and TIA Risk With Pulsed Field Ablation Compared to Radiofrequency Ablation in Atrial Fibrillation: Insights From a Large Prospective Registry

By MedXY 08/28/2026

This prospective registry reveals a significantly increased risk of stroke or transient ischemic attack within 30 days after pulsed field ablation compared to radiofrequency ablation for atrial fibrillation, highlighting important safety considerations and the need for careful surveillance.

AI Neurology news

Early Prediction of Upper-Limb Recovery Poststroke Using Machine Learning: A Clinically Feasible Approach

By MedXY 08/18/2026

A machine learning model using simple clinical tests within 72 hours poststroke accurately predicts 6-month upper-limb motor outcomes, aiding rehabilitation planning.

Neurology news

Neurotransmitter-Guided Connectome Disruption as a Key to Poststroke Language Impairment

By MedXY 08/15/2026

Damage to serotonergic and dopaminergic neurotransmitter-linked networks predicts variability in acute and chronic poststroke language impairment, offering new insights beyond traditional lesion metrics.

Neurology news

Reevaluating Acute Treatment Strategies for Spontaneous Spinal Cord Infarction: Insights from a Propensity Score-Matched Study

By MedXY 08/04/2026

This retrospective analysis reveals that standard antiplatelet therapy may reduce mortality compared to thrombolysis in acute spontaneous spinal cord infarction, highlighting the need for cautious therapeutic decisions pending stronger evidence.

Neurology news

MAD-MT Score: Enhancing Patient Selection for Mechanical Thrombectomy in Distal Vessel Occlusions

By MedXY 07/14/2026

The MAD-MT score integrates clinical and procedural factors to optimize mechanical thrombectomy decisions in distal and medium vessel occlusion strokes, guiding tailored treatment and improving functional outcomes.

Neurology news

Sex Differences in Large Vessel Occlusion Screening and Thrombectomy Outcomes: Insights from a Population-Based Cohort Study in Ontario

By MedXY 07/13/2026

This study reveals that female stroke patients are less frequently screened for large vessel occlusion (LVO) yet have a higher LVO prevalence and comparable thrombectomy use to males, with better long-term outcomes post-thrombectomy.

Cardiology Clinical Updates news

Impact of Cerebral Small Vessel Disease on Functional Decline: Insights from the Bleeding With Antithrombotic Therapy 2 Study and Related Evidence

By MedXY 07/03/2026

Cerebral small vessel disease (SVD) significantly contributes to functional decline independently of bleeding or ischemic events during antithrombotic therapy, underscoring the need for targeted management strategies to address SVD burden in cerebrovascular patients.

Neurology news Public Health

Long-Term Wildfire Smoke PM2.5 Exposure Is Linked to Higher Incident Stroke Risk in Older US Adults

By MedXY 06/05/2026

In a nationwide Medicare cohort, chronic wildfire smoke PM2.5 exposure was associated with a modest but significant increase in incident stroke, with stronger effects over longer exposure windows.

Neurology news Public Health

Long-Term Cognitive Recovery After Stroke: What the Oxford Cognitive Screen Reveals

By MedXY 05/20/2026

A long-term stroke study found that cognition improves most within 6 months, with memory and language recovering better than executive function. Early cognitive impairment was the strongest predictor of outcomes years later.

Emergency Medicine Neurology news

Stroke Disability and Mortality Post-ED Discharge for Dizziness: Rare but Clinically Significant

By MedXY 04/27/2026

A retrospective cohort study reveals that stroke-related disability or mortality after ED discharge for dizziness is rare (0.04% incidence), with most lesions occurring in the anterior fossa. Findings underscore the need for targeted risk stratification in dizziness evaluations.

Neurology news

EVT Shows Superior Outcomes in Anterior Cerebral Artery Occlusion Stroke: Insights from the ORIENTAL-MeVO Registry

By MedXY 04/25/2026

Endovascular thrombectomy (EVT) significantly improves 90-day functional outcomes in acute anterior cerebral artery occlusion stroke compared to standard medical management, without increasing hemorrhage or mortality risks, per the ORIENTAL-MeVO Registry.

Clinical Updates Neurology news

Inflammatory Biomarkers in Cerebral Venous Thrombosis: Prognostic Insights from the CLOT-VENUS Substudy and Meta-Analyses

By MedXY 04/22/2026

High admission levels of NLR, PLR, MLR, and SII are independently associated with poor functional outcomes and mortality in acute cerebral venous thrombosis, offering a low-cost tool for early risk stratification.

Neurology news

Real-Time fMRI Neurofeedback Shows Promise for Reading Rehabilitation in Post-Stroke Aphasia

By MedXY 04/14/2026

This feasibility RCT demonstrates that contingent fMRI neurofeedback targeting the left supramarginal gyrus can improve reading comprehension in stroke survivors with aphasia, outperforming both healthy controls and non-contingent neurofeedback approaches during early recovery.

Cardiology Neurology news

Mobile Health Intervention Achieves 24% Better Blood Pressure Control in Stroke Survivors: PINGS Trial Results from Ghana

By MedXY 04/13/2026

The PINGS trial demonstrates that a 12-month nurse-led mobile health intervention significantly improves blood pressure control among Ghanaian stroke survivors, with 67% achieving target BP versus 43% in usual care. This pragmatic approach leveraging task-shifting and basic mHealth tools offers a scalable model for resource-limited settings.

Clinical Updates Neurology news

Optimizing Prehospital Pathways: Impact of the Iranian Comprehensive Code Stroke Management Program (ICSM Phase III) on Thrombolysis Rates

By MedXY 03/11/2026

This review analyzes the ICSM Phase III study, highlighting how a structured empowerment program and standardized protocols in EMS significantly reduced prehospital delays and tripled alteplase administration rates for acute ischemic stroke.

Neurology news Psychiatry

Impact of the FKBP5 Gene on Stroke Recovery: A Comparative Study in Mice and Humans

By MedXY 03/10/2026

This translational study demonstrates that the FKBP5 protein, a regulator of the stress response, significantly influences stroke outcomes. Lower FKBP5 levels correlate with smaller brain lesions in mice, while high-expression genetic variants in humans are linked to poorer long-term functional recovery.

Clinical Updates Neurology news

Perihematomal Edema Dynamics and Functional Outcomes in Spontaneous Intracerebral Hemorrhage: Insights from a Global IPD Meta-Analysis

By MedXY 03/10/2026

This article synthesizes evidence from a large-scale individual participant data meta-analysis, demonstrating that early perihematomal edema growth (at 24 and 72 hours) is an independent predictor of death and disability after intracerebral hemorrhage.