Specialties – Medxy AI

Unveiling Respiratory Sensations in Adults with Congenital Central Hypoventilation Syndrome: Insights from Dyspnea Profiling During Rest and CO2 Rebreathing

By MedXY 10/28/2026

This article explores the surprising presence of conscious respiratory unpleasantness and dyspnea in adults with congenital central hypoventilation syndrome (CCHS) despite severely impaired central CO2 chemosensitivity, revealing potential alternative neural pathways for respiratory perception.

news Ophthalmology

Clinical Impact of Contact Lens Use in Fungal Keratitis: Insights from an 8-Year Retrospective Study

By MedXY 10/28/2026

This study compares contact lens-associated and non-contact lens-associated fungal keratitis, highlighting earlier presentation and better medical therapy outcomes in contact lens users versus a more complicated course in non-users.

news Pediatrics Respiratory

Intubation Duration Trumps Tracheostomy in Predicting Neurodevelopmental Outcomes in Severe BPD

By MedXY 10/28/2026

Prolonged intubation, rather than tracheostomy placement, is associated with poorer neurodevelopmental outcomes in infants with severe bronchopulmonary dysplasia, highlighting the need to reassess timing of airway interventions.

General Surgery news Oncology

Temporary Portal Vein Bypass in Pancreatectomy: Enhancing Safety in Complex Pancreatic Cancer Surgery

By MedXY 10/28/2026

Temporary mesoportal and mesocaval portal vein bypasses are effective surgical strategies in pancreatectomy with portal vein resection, offering comparable perioperative outcomes and facilitating safe resection of advanced pancreatic tumors.

news OB/GYN & Women's Health Oncology

Optimizing Steroid Tapering Strategies for Immunotherapy Toxicities in Gynecologic Cancers

By MedXY 10/28/2026

This study evaluates adherence to NCCN guidelines and taper durations of corticosteroids in managing severe immune-related adverse events (irAEs) among gynecologic cancer patients receiving immune checkpoint inhibitors, revealing that guideline discordance and shorter tapers lead to increased treatment escalation.

Gastroenterology Internal Medicine news

Integrating Therapies for Alcohol Use Disorder in Alcohol-Associated Hepatitis Clinical Trials: Advancing Composite Endpoints for Improved Outcomes

By MedXY 10/28/2026

Alcohol-associated hepatitis (AH) carries high morbidity and mortality, with no approved therapies addressing both liver injury and alcohol misuse. This article explores integrated trial designs using composite endpoints combining liver and alcohol-related outcomes, exemplified by the ITAALD trial.

Clinical Updates Neurology news

Differential Trajectories of Brain Atrophy in Multiple Sclerosis, MOGAD, and AQP4+ NMOSD: Unraveling the Impact of Disease Activity in MOGAD

By MedXY 10/28/2026

This review synthesizes evidence comparing brain atrophy patterns in MS, MOGAD, and AQP4+ NMOSD, highlighting MOGAD's atrophy association with inflammatory activity and lesion dynamics, emphasizing distinct pathogenic mechanisms and clinical trajectories.

Clinical Updates Diabetes & Endocrinology news OB/GYN & Women's Health

Low-Carbohydrate Diets, Nutritional Adequacy, Glycemia, and Perinatal Outcomes in Women With Gestational Diabetes Mellitus: Insights from the DiGest Trial and Contemporary Evidence

By MedXY 10/28/2026

This review synthesizes current evidence on low-carbohydrate diets in gestational diabetes mellitus (GDM), highlighting effects on glycemia, nutrient adequacy, and perinatal outcomes from the DiGest trial and supporting literature.

news Orthopedics

Enhanced Outcomes and Return-to-Sport Rates in Competitive Athletes Undergoing Contemporary Hip Arthroscopy for Femoroacetabular Impingement Syndrome

By MedXY 10/28/2026

Contemporary hip arthroscopy techniques for femoroacetabular impingement syndrome (FAIS) in athletes yield superior patient-reported outcomes and higher return-to-sport rates compared to early methods, highlighting advances in surgical management and rehabilitation.

Neurology news Psychiatry

Companionship’s Crucial Role in Enhancing Psychosocial Health Among Individuals with Spinal Cord Injury

By MedXY 10/28/2026

This study reveals companionship as a key mediator between marital status and mental health outcomes in individuals with spinal cord injury, highlighting the importance of relationship quality for psychosocial well-being.

news Orthopedics Plastic Surgery

Enhancing Horizontal Ridge Augmentation: Efficacy of rhBMP-2 Loaded Volume-Stable Collagen Matrix Versus Guided Bone Regeneration

By MedXY 10/28/2026

This preclinical canine study demonstrates that rhBMP-2 delivered via a volume-stable collagen matrix significantly improves horizontal ridge augmentation compared to conventional guided bone regeneration techniques, suggesting potential for clinical application in dental implantology.

Cardiology Neurology news

Atorvastatin in Older Adults: Balancing Cardiovascular Prevention and Disability-Free Survival

By MedXY 10/28/2026

A landmark randomized trial demonstrates that atorvastatin reduces major cardiovascular events in adults aged 70 and older without established cardiovascular disease but does not extend disability-free survival, highlighting nuanced considerations for primary prevention.

Diabetes & Endocrinology news OB/GYN & Women's Health

Implications of Hemithyroidectomy on Gestational Hypothyroidism and Pregnancy Outcomes: Insights from a Nationwide Matched Cohort

By MedXY 10/28/2026

This study reveals that prior hemithyroidectomy increases the risk of gestational hypothyroidism and later gestation complications, including preterm birth or pregnancy loss, underscoring the need for vigilant thyroid monitoring during pregnancy.

Cardiology news

Inflammation Biomarker CRP Predicts Functional Gains from Physical Rehabilitation in Older Adults Hospitalized with Heart Failure

By MedXY 10/28/2026

Elevated baseline CRP levels in older acute HF patients identify those who gain the most physical function improvement from a 12-week rehabilitation program, supporting biomarker-guided therapy.

news Nursing & care Public Health

Modernising Functional Independence Measurement: Validation of a Contemporary Extended Activities of Daily Living Scale in a Mixed Sample

By MedXY 10/28/2026

This study validates a new Contemporary Extended Activities of Daily Living scale, showing it reliably measures functional independence by including modern tasks alongside traditional ones in adults over 60 with chronic conditions.

Dentistry General Surgery news

Two-Year Outcomes of 3D-Printed Complete Dentures: Efficacy and Patient Satisfaction in Edentulous Care

By MedXY 10/28/2026

This multicenter study evaluates the 2-year clinical success, survival, and patient-reported outcomes of 3D-printed complete dentures, demonstrating high durability and stable oral quality of life in edentulous patients.

Allergy & Immunology Clinical Updates news

Oral Deucrictibant for On-Demand Treatment of Hereditary Angioedema Attacks: A Phase 3, Multicentre, Randomised, Double-Blind, Placebo-Controlled Crossover Trial and Related Evidence

By MedXY 10/28/2026

This review synthesizes phase 3 RAPIDe-3 trial results demonstrating oral deucrictibant's rapid efficacy and safety for hereditary angioedema attacks, contextualized with phase 2 studies and prophylactic applications, highlighting its potential to transform management of bradykinin-mediated angioedema.

Gastroenterology news Pediatrics

Driving Legislative Change for Access to Medications in Pediatric Inflammatory Bowel Disease

By MedXY 10/28/2026

A pediatric IBD patient's medication denial due to lack of pediatric FDA labeling prompted physician-led advocacy, resulting in a state law mandating insurance coverage for pediatric medications with adult approval and supporting data.

Hematology-Oncology news Rheumatology

Peripheral Blood UBA1 Variant Burden as a Prognostic Biomarker in VEXAS Syndrome: Insights from a Nationwide Prospective Study

By MedXY 10/28/2026

This prospective nationwide study identifies baseline peripheral blood UBA1 variant allele frequency as a robust predictor of poor outcomes in VEXAS syndrome, providing a new tool for risk stratification and management.

Nephrology news

Race-Neutral eGFR and Kidney Transplant Equity: Early Impacts on Black Patients at a Single Center

By MedXY 10/28/2026

A new OPTN policy removing race from eGFR calculations shows promise in increasing kidney transplantation access for Black patients by adding waiting time credits, while not disadvantaging others on the waitlist.