葡萄膜黑色素瘤的15-GEP/PRAME检测预后价值：有无确认性细胞病理学的比较
Posted innews Ophthalmology Pathology & Lab Medicine

Prognostic Value of 15-GEP/PRAME Assay With or Without Confirmatory Cytopathology in Uveal Melanoma: Insights From the Collaborative Ocular Oncology Group Study 2

This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is unavailable.
Earlier Disclosure of Blood-Based Biomarkers Enhances Diagnostic Certainty and Clinical Management in Cognitive Disorders: A Review of a Recent Randomized Clinical Trial
Posted inClinical Updates Neurology news Pathology & Lab Medicine

Earlier Disclosure of Blood-Based Biomarkers Enhances Diagnostic Certainty and Clinical Management in Cognitive Disorders: A Review of a Recent Randomized Clinical Trial

Early disclosure of plasma p-tau217 and NfL biomarkers significantly improves diagnostic confidence and clinical decisions in cognitive decline without increasing emotional distress, supporting their integration into routine memory clinic care.
Differentiating Allergic Fungal Rhinosinusitis from Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: Insights from Structured Histopathology in a Saudi Cohort
Posted innews Otorhinolaryngology Pathology & Lab Medicine

Differentiating Allergic Fungal Rhinosinusitis from Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: Insights from Structured Histopathology in a Saudi Cohort

This study delineates distinct clinical, radiographic, laboratory, and histopathologic features separating allergic fungal rhinosinusitis from eosinophilic chronic rhinosinusitis with nasal polyps in a Middle Eastern tertiary-care cohort.