Internal Medicine

Hospital Discharge Prescriptions for Alcohol Use Disorder: Unveiling Key Predictors to Bridge the Treatment Gap

By MedXY 11/01/2026

Despite proven benefits, medications for alcohol use disorder remain underprescribed at hospital discharge. This study identifies hospitalization and patient factors influencing new prescriptions, highlighting opportunities to enhance AUD treatment integration in inpatient settings.

Clinical Updates Dentistry Internal Medicine

Comparative Cost-Effectiveness of Non-Surgical Periodontal Therapies in General Practice

By MedXY 10/31/2026

A cost consequence analysis demonstrated that guided periodontal infection control (GPIC) is less costly than conventional non-surgical therapy (CNST) while achieving similar periodontal health outcomes at six months.

Clinical Updates Internal Medicine Psychiatry

Sustaining Behavioral Insomnia Care in VA PCMHI Clinics: Impact of Implementation Strategy Withdrawal on Treatment Delivery and Medication Use

By MedXY 10/31/2026

This study evaluates the sustainment of brief behavioral insomnia treatments in VA primary care mental health clinics after implementation support ended, showing increased therapy delivery and reduced sleep medication prescriptions.

Clinical Updates Diabetes & Endocrinology Internal Medicine

Skeletal Muscle and Lipid Metabolism Disruption in Male Hypogonadism: Insights from Interventional Metabolomic Profiling

By MedXY 10/31/2026

An interventional study reveals testosterone’s tissue-specific effects on lipid metabolism, highlighting skeletal muscle as a critical site of metabolic disruption in male hypogonadism and its cardiometabolic implications.

Clinical Updates Internal Medicine Nephrology

Sibeprenlimab Demonstrates Kidney Function Preservation in IgA Nephropathy: Insights from the Final Phase 3 VISIONARY Trial

By MedXY 10/30/2026

The phase 3 VISIONARY trial establishes sibeprenlimab as a promising therapy in IgA nephropathy, significantly stabilizing eGFR decline and reducing kidney-function deterioration over 24 months with a favorable safety profile.

Internal Medicine Rehabilitation Medicine

Cross-Acclimation Effects of Dry and Humid Heat Adaptation on Endurance Performance

By MedXY 10/29/2026

This study investigated how acclimation to dry versus humid heat affects endurance cycling performance and physiological responses, revealing environment-specific and cross-environmental benefits for athletes.

Internal Medicine news Rheumatology

DNA Methylation Signatures Distinguish Gout from Asymptomatic Hyperuricaemia and Align with Genetic Risk at Immune-Metabolic Loci

By MedXY 10/29/2026

This study identifies specific DNA methylation patterns in blood that differentiate gout patients from those with asymptomatic hyperuricaemia and normouricaemic controls, linking epigenetic changes to immune-metabolic genetic risk factors and offering potential for molecular disease stratification.

Internal Medicine Neurology news

Impact of the 2016 CDC Opioid Guideline on Analgesic Prescribing in Older Adults with Dementia: Trends and Clinical Implications

By MedXY 10/29/2026

This study examines how the 2016 CDC opioid prescribing guideline influenced opioid and gabapentinoid use in older adults with dementia, revealing shifts in analgesic prescribing patterns but uncertain effects on symptom management.

Gastroenterology Internal Medicine news

Integrating Therapies for Alcohol Use Disorder in Alcohol-Associated Hepatitis Clinical Trials: Advancing Composite Endpoints for Improved Outcomes

By MedXY 10/28/2026

Alcohol-associated hepatitis (AH) carries high morbidity and mortality, with no approved therapies addressing both liver injury and alcohol misuse. This article explores integrated trial designs using composite endpoints combining liver and alcohol-related outcomes, exemplified by the ITAALD trial.

Internal Medicine news Public Health

Navigating the Balance: Fostering Humanistic Practice Amidst Healthcare System Pressures

By MedXY 10/27/2026

This qualitative study explores practicing physicians’ experiences with humanistic practice, revealing how relationships and resilience foster compassion despite systemic challenges like efficiency demands and standardized care models.

Internal Medicine Nephrology news

Optimizing Early Mycophenolate Mofetil Dosing Post-Kidney Transplant: A Nomogram Integrating Triglycerides and Body Weight

By MedXY 10/26/2026

A novel nomogram using pretransplant triglycerides and body weight shows promise to guide early mycophenolate mofetil dosing after kidney transplantation, potentially reducing drug overexposure before therapeutic drug monitoring is feasible.

Clinical Updates Internal Medicine Public Health

Non-Attendance in Exercise Therapy Among Multimorbid Patients: Insights from the MOBILIZE Trial

By MedXY 10/26/2026

This study examines characteristics and reasons behind non-attendance to exercise and self-management sessions among multimorbid patients, highlighting younger age, lower self-efficacy, and depressive symptoms as key factors.

Internal Medicine news Superintelligence

Enhancing Ambulatory Care: Patient Experiences with Ambient AI Scribes

By MedXY 10/25/2026

This qualitative study explores how ambient AI scribes affect ambulatory patient experience, revealing improvements in communication, visit thoroughness, and patient comfort influenced by demographic and relational factors.

Internal Medicine Neurology news

Vascular Risk Factors as Key Contributors to Late-Onset Epilepsy: Insights from a Large US Cohort Meta-Analysis

By MedXY 10/25/2026

A comprehensive meta-analysis of six US cohorts identifies vascular risk factors including smoking, hypertension, diabetes, chronic kidney disease, stroke history, and APOE ε4 genotype as significant predictors of late-onset epilepsy in older adults.

Internal Medicine news Superintelligence

AI-Derived Panoramic Radiograph Score Links Oral Health to Major Systemic Diseases

By MedXY 10/24/2026

An AI-generated panoramic dental imaging score correlates independently with diabetes, hypertension, ischemic heart disease, osteoporosis, and hyperlipidemia, supporting integrated medical-dental care.

Internal Medicine news Respiratory

Unraveling Racial Disparities in Respiratory Tract Infection Diagnoses and Antibiotic Prescribing Patterns

By MedXY 10/24/2026

Racial disparities in respiratory tract infection diagnoses partially explain lower antibiotic prescribing rates in non-White patients, highlighting the need for equitable clinical assessment and antibiotic stewardship.

Internal Medicine news OB/GYN & Women's Health

Bridging the Gap: Addressing Low Breast Cancer Screening Rates Among Resident Physicians in Academic Primary Care

By MedXY 10/24/2026

Resident physicians demonstrate lower breast cancer screening rates compared to faculty, even in well-supported academic practices. Adjusting for patient and physician factors narrows, but does not eliminate, this gap, underscoring the need to redesign residency training to improve preventive care delivery.

Diabetes & Endocrinology Internal Medicine news

Enhancing Glycemic Control in Non-Insulin-Treated Type 2 Diabetes with Continuous Glucose Monitoring: New Evidence from the CONNECT Trial

By MedXY 10/24/2026

The CONNECT trial demonstrates that continuous glucose monitoring (CGM) significantly improves glycemic control in adults with non-insulin-treated type 2 diabetes managed in primary care, reducing HbA1c levels and hyperglycemia risk without increasing hypoglycemia.

Internal Medicine Nephrology news

Ultrasound-Derived Renal Parenchymal Volume Indexed to BMI: A Novel Predictor of One-Year Kidney Graft Function

By MedXY 10/23/2026

Indexing donor kidney parenchymal volume by recipient BMI via routine ultrasound strongly predicts one-year kidney graft function, offering a practical surrogate for graft-recipient size matching.

Internal Medicine news Psychiatry

Integrating Pharmacists into Opioid Use Disorder Care: Feasibility and Acceptability in Primary Care Settings

By MedXY 10/23/2026

A nonrandomized clinical trial demonstrates that incorporating pharmacists into primary care teams to manage opioid use disorder enhances feasibility, reduces care barriers, and maintains high acceptability among providers and patients.