Mobile Units for Integrated Addiction and HIV Prevention Services for People Who Inject Drugs: Insights from the HPTN 094 Randomized Clinical Trial
Posted inClinical Updates HIV/AIDS Psychiatry

Mobile Units for Integrated Addiction and HIV Prevention Services for People Who Inject Drugs: Insights from the HPTN 094 Randomized Clinical Trial

This review synthesizes evidence from the HPTN 094 trial assessing mobile integrated PrEP and MOUD services versus peer navigation for people who inject drugs, highlighting key outcomes, limitations, and implications for HIV prevention and addiction treatment delivery.
正念导向康复增强如何重塑阿片类物质使用障碍的前额叶皮层：来自随机对照试验的神经生物学与临床启示
Posted inClinical Updates Psychiatry

Prefrontal Cortical Remodeling via Mindfulness-Oriented Recovery Enhancement in Opioid Use Disorder: Neurobiological and Clinical Insights from a Randomized Controlled Trial

Mindfulness-Oriented Recovery Enhancement (MORE) modulates prefrontal cortical activity, reduces craving, and prolongs abstinence in opioid use disorder by rebalancing neural responses to drug and natural rewards, substantiating its role as an adjunct to pharmacotherapy.
多模态机器学习预测重性抑郁障碍复发：现有证据与未来方向
Posted inClinical Updates Psychiatry Superintelligence

Multimodal Machine Learning-Based Prediction of Relapse in Major Depressive Disorder: Current Evidence and Future Directions

This review synthesizes recent evidence on machine learning models integrating multimodal data for relapse prediction in MDD, highlighting moderate accuracy driven mainly by clinical risk factors and advocating for dynamic approaches to better capture longitudinal relapse trajectories.
Noncombustible Nicotine or Tobacco Product Use After Smoking Cessation and Major Vision-Impairing Diseases: Evidence from a Nationwide Cohort Study and Clinical Implications
Posted inClinical Updates Psychiatry Public Health

Noncombustible Nicotine or Tobacco Product Use After Smoking Cessation and Major Vision-Impairing Diseases: Evidence from a Nationwide Cohort Study and Clinical Implications

This review synthesizes current evidence on the association between switching from combustible cigarettes to noncombustible nicotine/tobacco products and the risk of major vision-impairing eye diseases, highlighting a nationwide Korean cohort study showing modest increased risk compared to complete cessation.