Infectious Diseases

Fast, Broad Oseltamivir Prophylaxis May Cut Hospitalizations During Nursing Home Influenza Outbreaks

By MedXY 06/15/2026

In a large target-trial emulation across US nursing homes, starting oseltamivir prophylaxis within 2 days for at least 70% of eligible residents was associated with fewer hospitalizations, but not lower short-term mortality.

Infectious Diseases news Nursing & care

Early, Broad Oseltamivir Prophylaxis May Cut Hospitalizations in Nursing Home Influenza Outbreaks

By MedXY 06/15/2026

Prompt oseltamivir prophylaxis covering at least 70% of eligible nursing home residents within 2 days of outbreak detection was associated with fewer hospitalizations, but not lower mortality.

Infectious Diseases news Nursing & care

Fast, Broad Oseltamivir Use in Nursing Home Flu Outbreaks May Cut Hospitalizations

By MedXY 06/15/2026

In a real-world target trial emulation, starting oseltamivir prophylaxis within 2 days for at least 70% of eligible nursing home residents was linked to fewer hospitalizations, but not lower short-term mortality.

Gastroenterology Infectious Diseases news

Post-infection Gut-Brain Disorders Affect About 1 in 10 People With DGBI Worldwide, With Distinct Psychological and Regional Patterns

By MedXY 06/10/2026

A large 26-country survey found that post-infection disorders of gut-brain interaction account for 10.5% of DGBI cases and are linked to younger age, male sex, urban living, anxiety, and greater somatic symptom burden.

Cardiology Infectious Diseases news

Culture-Negative Infective Endocarditis in the Modern Diagnostic Era: Patient Characteristics and Heterogeneity in a Nationwide Cohort

By MedXY 06/10/2026

A nationwide Danish study found that culture-negative infective endocarditis was less common than previously reported, often presented without fever or sepsis, and showed higher embolic risk. PET-CT was especially useful in prosthetic valve cases.

Gastroenterology Infectious Diseases news

When a Stomach Bug Doesn’t End: The Hidden Global Burden of Post-Infection Gut Disorders

By MedXY 06/10/2026

A major global study shows that some people develop lasting gut-brain disorders after acute gastroenteritis, linking infections to chronic digestive and psychological symptoms.

Gastroenterology Infectious Diseases news

HBsAg Seroclearance Lowers Hepatocellular Carcinoma Risk Beyond Viral Suppression in Cirrhosis, but Does Not Reduce Hepatic Decompensation

By MedXY 06/10/2026

In NA-treated cirrhotic chronic hepatitis B with complete viral suppression, HBsAg seroclearance was linked to lower HCC risk but not lower hepatic decompensation, reinforcing functional cure as a meaningful but incomplete clinical endpoint.

Diabetes & Endocrinology Infectious Diseases news

Swedish Population Data Suggest SARS-CoV-2 Infection and COVID-19 Vaccination Do Not Confer a Sustained Causal Risk of New-Onset Type 1 Diabetes

By MedXY 06/07/2026

In a nationwide Swedish cohort, type 1 diabetes diagnoses rose briefly after SARS-CoV-2 infection and first vaccine dose, but the signal was short-lived, supporting diagnostic acceleration rather than a durable causal effect.

Critical Care Infectious Diseases news

Impact of Appropriate Antimicrobial Therapy on ICU Patient Outcomes: Subanalysis of the DIANA Study Dataset

By MedXY 06/05/2026

In critically ill ICU patients with confirmed bacterial infections, appropriate empiric antimicrobial therapy was common and independently linked to lower 28-day mortality and more antimicrobial-free days.

Emergency Medicine Infectious Diseases news

Digital Shared Decision Support Increased STI Testing for Adolescents and Young Adults in the Emergency Department

By MedXY 05/30/2026

In a randomized controlled trial, the STIckER smartphone-based decision aid increased gonorrhea/chlamydia and pharyngeal STI testing in emergency department patients aged 14 to 24 years, while improving decisional clarity, satisfaction, and implementation acceptability.

Dermatology Infectious Diseases news

Large-Scale Meta-Analysis Finds Higher Influenza and Shingles Risk with JAK-STAT Inhibitors

By MedXY 05/27/2026

A large meta-analysis found JAK-STAT inhibitors slightly increased influenza, bronchitis, and herpes zoster risk, especially in atopic dermatitis, while serious and opportunistic infections were not significantly increased.

Family Medicine & Nutrition Infectious Diseases news

Rapid Respiratory Point-of-Care Testing and Antibiotic Use in Primary Care: A Randomized Clinical Trial

By MedXY 05/22/2026

A randomized trial found that rapid respiratory point-of-care testing did not reduce same-day antibiotic prescribing in primary care, though it was safe and may help when a virus is detected.

Gastroenterology Infectious Diseases news

Diabetes, Male Sex, and Low HBsAg, HDV RNA, and ALT Predict Spontaneous HDV Suppression in Chronic Hepatitis D

By MedXY 05/20/2026

In 1,610 untreated chronic hepatitis D patients, spontaneous HDV suppression was uncommon but increased over time. Diabetes, male sex, and lower baseline HBsAg, HDV RNA, and ALT predicted suppression and fewer liver-related events.

Infectious Diseases news Respiratory

Lower Airway Dysbiosis in NTM-Positive Bronchiectasis Is Linked to NET-Dominant Severe Phenotypes

By MedXY 05/18/2026

In NTM-positive bronchiectasis, lower airway dysbiosis involving Mycobacterium and oral bacteria is linked to higher NET levels and more severe disease phenotypes, suggesting that the broader airway microbiome may shape inflammation and outcomes.

$New SCCM–ESICM Consensus Defines Refractory Septic Shock$

Critical Care Infectious Diseases news

New SCCM–ESICM Consensus Defines Refractory Septic Shock

By MedXY 05/15/2026

A new SCCM–ESICM Delphi consensus standardizes clinical criteria for refractory septic shock, focusing on persistent hypoperfusion, fluid unresponsiveness, high vasopressor needs, and bedside ultrasound when mixed shock is suspected.

Infectious Diseases news OB/GYN & Women’s Health

First-Trimester Maternal CMV Infection Concentrates the Risk of Fetal Brain Injury, Hearing Loss, and Autism Spectrum Disorder

By MedXY 05/11/2026

A large prospective cohort suggests that long-term sequelae of congenital CMV after primary maternal infection are confined to first-trimester exposure, with autism spectrum disorder linked to temporal lobe white matter abnormalities.

Hematology-Oncology Infectious Diseases news

Bone Marrow Immune Profiling Identifies a Practical Infection Risk Score in Multiple Myeloma

By MedXY 05/09/2026

A large multicenter study links specific bone marrow immune cell patterns to infection risk in multiple myeloma and proposes a clinically relevant immune score that may support minimally invasive monitoring.

Infectious Diseases news Public Health

Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban

By MedXY 05/09/2026

A molecular epidemiology study in Durban found that casual community contact, not only household or named contacts, accounted for a substantial share of drug-resistant tuberculosis transmission.

Infectious Diseases news Public Health

“Never More Than 15 Feet From the Respirator”: Housestaff Research During the 1955 Boston Polio Epidemic

By MedXY 05/05/2026

During Boston's devastating 1955 polio epidemic, Massachusetts General Hospital trainees conducted groundbreaking patient research while providing round-the-clock care in iron lung wards – a striking contrast to trainee roles during COVID-19.

Gastroenterology Infectious Diseases news

Pairing HDV RNA With Anti-HDV Levels May Sharpen Staging and Treatment Monitoring in HBV/HDV Coinfection

By MedXY 05/04/2026

In HBsAg-positive, anti-HDV-positive patients, combined measurement of HDV RNA and anti-HDV titers distinguished inactive from active disease and tracked interferon response more effectively than either marker alone.