Infectious Diseases

HEPA Filters in Care Homes: No Reduction in Winter Respiratory Infections According to AFRI-c Trial

By MedXY 08/03/2026

The AFRI-c trial found no significant reduction in respiratory infection rates or staff absenteeism in care homes using HEPA filters during winter, highlighting the need to maintain established infection control measures.

Cardiology Infectious Diseases news

Navigating Uncertainty: Rapid Evidence Generation and Translation of Anticoagulation Strategies in Noncritically Ill COVID-19 Patients

By MedXY 07/30/2026

This article reviews the accelerated evidence generation for anticoagulation in noncritically ill COVID-19 patients, highlighting how coordinated trials and data sharing influenced clinical guidelines and patient outcomes during the pandemic.

Infectious Diseases news Ophthalmology

Fungal Endophthalmitis Associated with Contaminated Trypan Blue in Cataract Surgery: A Retrospective Case Series

By MedXY 07/24/2026

Six cases of postoperative fungal endophthalmitis caused by Sarocladium kiliense following cataract surgery involving contaminated trypan blue are reported, highlighting diagnosis, management, and outcomes.

$Combining Tissue Hypoperfusion Markers with Vasopressor Dose Enhances Mortality Risk Stratification in Refractory Septic Shock$

Critical Care Infectious Diseases news

Combining Tissue Hypoperfusion Markers with Vasopressor Dose Enhances Mortality Risk Stratification in Refractory Septic Shock

By MedXY 07/21/2026

Persistent tissue hypoperfusion alongside vasopressor dosing improves early risk stratification in refractory septic shock, identifying patients with markedly increased 28-day mortality beyond vasopressor dose alone, as shown in a secondary analysis of the ANDROMEDA-SHOCK-2 trial.

Infectious Diseases news Plastic Surgery

Reducing Surgical-Site Infection in Implant-Based Breast Reconstruction: Clinical Impact of the GAPS Protocol over Five Years

By MedXY 07/18/2026

The GAPS protocol significantly reduced surgical-site infections in implant-based breast reconstruction over five years, suggesting structured perioperative infection control enhances patient outcomes and healthcare efficiency.

Critical Care Infectious Diseases news

Early Shenfu Injection in Sepsis: Impact on Hemodynamics, Mortality, and Microcirculation in a Multicenter RCT

By MedXY 07/17/2026

Early administration of Shenfu injection in septic ICU patients did not reduce vasopressor use but was associated with lower mortality and improved microcirculation, warranting further validation.

Clinical Updates Gastroenterology Infectious Diseases news

Hepatitis C Screening Among Persons Experiencing Homelessness in Emergency Departments: Insights from the DETECT Hep C Screening Trial and Related Evidence

By MedXY 07/17/2026

Emergency departments serve as vital venues for hepatitis C virus screening, particularly for persons experiencing homelessness who exhibit higher HCV prevalence and face healthcare access barriers. Evidence supports nontargeted screening in EDs to improve detection and engagement in this vulnerable population.

Gastroenterology Infectious Diseases news

Unraveling the Diarrheal Outbreaks: Understanding Cyclospora and Cryptosporidiosis in the United States

By MedXY 07/17/2026

This article explores recent outbreaks of Cyclospora and Cryptosporidium infections in the U.S., their transmission, clinical features, diagnosis, treatment, and prevention, highlighting the public health impact and clinical challenges.

Infectious Diseases news Respiratory

Decoding the Pulmonary Immune Landscape in Influenza: Insights from a Large-Scale Single-Cell Atlas

By MedXY 07/17/2026

A comprehensive single-cell atlas of lung immune cells reveals distinct immune responses in mild versus severe influenza, highlighting neutrophil dysfunction and lymphocyte impairment as key drivers of pathology.

Critical Care Infectious Diseases news

Harnessing Precision Medicine: The APS Consortium’s National Platform for Phenotyping ARDS, Pneumonia, and Sepsis

By MedXY 07/15/2026

The APS Consortium establishes a large, prospective cohort of critically ill adults with ARDS, pneumonia, and sepsis to enable biologically based phenotyping, leveraging rich clinical data and biospecimens for improved understanding and therapeutic development.

Infectious Diseases news OB/GYN & Women’s Health

Persistent Elevated Risk of Severe COVID-19 Outcomes in Pregnant and Postpartum Individuals Beyond the Pandemic Emergency

By MedXY 07/10/2026

Pregnant and postpartum individuals continue to face higher risks of severe COVID-19 outcomes, including hospitalization and pneumonia, even after the pandemic emergency has ended, emphasizing the need for ongoing vigilance and tailored clinical management.

Gastroenterology Infectious Diseases news

Unraveling Hepatitis B-Induced Liver Fibrosis: The Critical Role of Pyruvate, PPARα, and Reactive Oxygen Species

By MedXY 07/10/2026

This article explores the mechanism by which HBV induces liver fibrosis through pyruvate-dependent ROS production and PPARα inhibition, highlighting novel therapeutic targets for chronic hepatitis B management.

Infectious Diseases news Nursing & care Pathology & Lab Medicine Respiratory

Point-of-Care Multiplex PCR Testing in Nursing Homes: Impact on Respiratory Outbreak Management and Emergency Transfers

By MedXY 07/09/2026

A cluster randomized trial in Toronto nursing homes found that on-site multiplex PCR testing improved viral detection and reduced emergency department transfers during respiratory outbreaks, though it did not alter outbreak size or frequency.

Infectious Diseases Neurology news

Long-term Neurological Sequelae in Adult Survivors of Ebola Virus Disease: Insights from a 7-Year Liberian Cohort Study

By MedXY 07/05/2026

This study characterizes neurological complications in adult Ebola survivors over 7 years, demonstrating persistent cognitive and neuropsychiatric deficits despite gradual improvement, underscoring the need for ongoing neurological follow-up.

Infectious Diseases news OB/GYN & Women’s Health

Ebola Virus in Pregnancy: Current Insights and Clinical Implications During the DR Congo Outbreak

By MedXY 07/03/2026

This article reviews updated clinical understanding of Ebola virus disease in pregnancy amid the Democratic Republic of Congo outbreak, highlighting maternal outcomes, risks of vertical transmission, treatment challenges, and the critical need for inclusion of pregnant individuals in therapeutic trials.

Critical Care Infectious Diseases news

Clinical Metagenomics in Sepsis: Insights from the DigiSep Randomized Controlled Trial

By MedXY 07/02/2026

The DigiSep trial assessed the impact of metagenomic next-generation sequencing (mNGS) on sepsis outcomes. While primary endpoint improvement was not significant, secondary analyses revealed benefits in mechanical ventilation duration, shock resolution, and quality of life without raising healthcare costs.

Infectious Diseases news Public Health

Evaluating the Safety of Same-Day COVID-19 and Influenza Vaccination: Insights from a Large Veterans Affairs Target Trial Emulation

By MedXY 07/02/2026

A large U.S. Veterans Affairs study found no increased 90-day risk of adverse events after same-day COVID-19 and influenza vaccination compared to influenza vaccination alone, supporting the safety of coadministration with updated COVID-19 formulations.

Critical Care Infectious Diseases news

Therapeutic Implications of MARS Therapy-Induced Piperacillin Clearance in Critical Liver Failure Patients

By MedXY 06/30/2026

MARS therapy significantly reduces total plasma piperacillin levels by approximately one-third per session in critically ill liver failure patients, underscoring the need for therapeutic drug monitoring and individualized antibiotic dosing.

Infectious Diseases news Ophthalmology

Long-Term Assessment of Rose Bengal Photodynamic Therapy in Infectious Keratitis: Insights from the REAGIR Randomized Trial

By MedXY 06/29/2026

A 12-month follow-up of the REAGIR trial found no significant benefit of adjunctive rose bengal photodynamic therapy with green light over sham treatment in improving visual acuity, scar size, or complication rates in infectious keratitis.

Clinical Updates Gastroenterology Infectious Diseases news

Functional Anti-preS1 Antibody Responses and Their Role in Viral Control in Chronic Hepatitis B

By MedXY 06/28/2026

This review synthesizes evidence on preS1 antigen and anti-preS1 IgG dynamics in chronic hepatitis B, highlighting their correlations with viral replication, liver inflammation, and functional cure, and elucidates the neutralising potential of anti-preS1 antibodies as markers of endogenous viral control.