A large UK cohort study reveals that beta-blockers reduce mortality in COPD patients with heart failure or ischemic heart disease, but concurrent long-acting beta-agonists may attenuate this benefit.
The 2026 ESC clinical consensus outlines creation of multidisciplinary Women’s Heart Centres to close gaps in diagnosis, management, and research for women’s cardiovascular disease across the life course.
This review synthesizes current evidence on the impact of hypoglossal nerve stimulation (HGNS) on cardiovascular disease incidence in obstructive sleep apnea patients, highlighting potential long-term cardiovascular benefits and mechanistic insights.
A comprehensive nationwide study reveals that maternal diabetes during pregnancy, particularly pregestational diabetes, significantly increases offspring's risk of early-onset cardiovascular diseases, mediated partly by perinatal complications.
This review synthesizes evidence that high adolescent cardiorespiratory fitness slightly elevates early adult atrial fibrillation risk but substantially reduces cardiovascular disease incidence later in life, with familial confounders accounted for through sibling analysis.
This large-scale study links specific PM2.5 components, especially chloride, black carbon, and sulfate, to increased long-term cardiovascular disease risk, emphasizing targeted pollution control for better heart health.
A large-scale Dutch cohort study reveals that women with a history of spontaneous preterm birth face a significantly elevated risk of cardiovascular mortality, with the highest risk observed in those delivering before 32 weeks of gestation.
Thyroid dysfunction reshapes lipid metabolism, vascular tone, cardiac performance, and rhythm. Cardiovascular risk is clearest at the extremes of thyroid status, while treatment decisions in subclinical disease should remain individualized.
Higher proteinuria in preeclampsia was linked to greater long-term risk of maternal hypertension and chronic kidney disease, with overall increased risk of cardiovascular disease as well.
A nationwide study reveals that eclampsia patients face a 6.9-fold increased risk of cardiovascular disease readmission within the first year postpartum, with stroke risk nearly 13 times higher than normotensive patients. These findings underscore the critical need for enhanced early postpartum cardiac surveillance in women with eclampsia history.
A large-scale proteomic meta-analysis across five cohorts identified 15 novel plasma protein markers for venous thromboembolism, highlighting the roles of the extracellular matrix, immunity, and vascular senescence in disease risk and offering potential new targets for clinical prevention.
This article explores the transformation of lipid management through PCSK9 inhibitors. From genetic discovery to landmark cardiovascular outcomes trials, we examine how monoclonal antibodies, RNA interference, and gene editing are redefining the boundaries of LDL-C reduction and patient care in atherosclerotic disease.
A comprehensive simulation study evaluates the cost-effectiveness of semaglutide for secondary cardiovascular prevention in US adults without diabetes, finding significant health benefits but highlighting the need for price reductions to ensure economic sustainability.
A longitudinal analysis from the SWAN study indicates that women treated with levothyroxine for hypothyroidism do not face a higher risk of cardiovascular events compared to those without thyroid disease, providing clinical reassurance for long-term management during the menopause transition.
This emulation study applies SELECT trial data to over 600,000 individuals, suggesting that GLP-1RAs could significantly reduce 10-year cardiovascular risk in high-risk obese populations without existing disease, offering a potential 22% relative risk reduction.
This review synthesizes findings on how pregnancy biomarkers, particularly sFlt-1 and hs-cTnI, serve as early indicators of long-term maternal cardiovascular risk, offering a unique window for sex-specific prevention.
Recent data from the ARIC study and emerging expert consensus are redefining primary aldosteronism. Rather than a rare, all-or-nothing condition, it is now viewed as a broad spectrum where even subclinical elevations significantly increase the risk of atrial fibrillation and stroke in older adults.
This review synthesizes findings from a 21-
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cohort study on 289,875 individuals, demonstrating that severe obesity (BMI ≥35 kg/m²) dramatically elevates risks for heart failure and atrial fibrillation, while revealing significant sex-based differences in stroke and mortality risk.
A major AHA scientific statement forecasts a significant increase in cardiovascular disease and risk factors among U.S. women by 2050. It highlights rising rates of obesity and hypertension while emphasizing the urgent need for targeted interventions across the lifespan to mitigate this public health crisis.
This article examines the CHIIP study, a randomized clinical trial evaluating whether survivorship care plan-based counseling improves cardiovascular risk factor control in childhood cancer survivors. Findings suggest that while documentation improved, counseling did not significantly outperform simple risk assessments.
