Specialties – Page 4

$Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus$

Acute Brain Injury in New-Onset Refractory Status Epilepticus and Etiology-Defined Status Epilepticus

By MedXY 06/10/2026

This study found that cryptogenic NORSE causes severe, rapidly rising neuroaxonal injury, measured by NfL, and that higher NfL predicts worse short-term outcome. S100B was not useful for distinguishing groups.

news Oncology

The Oncology Care Model and Starting Systemic Therapy for Cancer

By MedXY 06/10/2026

A Medicare-based study found the Oncology Care Model did not increase systemic therapy starts for newly diagnosed cancer and was linked to less treatment initiation and lower spending in poor-prognosis cancer.

Cardiology news

Great Debate: Is the New Risk Factor-Weighted Clinical Likelihood Model Useful for Estimating Pre-Test Probability of Obstructive Coronary Artery Disease?

By MedXY 06/10/2026

The RF-CL model is a new ESC-recommended tool for estimating the pre-test probability of obstructive CAD in suspected chronic coronary syndromes. It improves risk stratification and may reduce unnecessary testing, though symptom interpretation and practical limits remain debated.

Cardiology Hematology-Oncology news

The Fibrinogen αC Region Promotes Arterial Thrombosis in Hypofibrinogenemia

By MedXY 06/10/2026

Low fibrinogen alone did not prevent arterial thrombosis in humans or mice, but loss of the fibrinogen αC region reduced clot formation. The study suggests fibrinogen structure, not just level, influences arterial thrombotic risk.

Gastroenterology Infectious Diseases news

When a Stomach Bug Doesn’t End: The Hidden Global Burden of Post-Infection Gut Disorders

By MedXY 06/10/2026

A major global study shows that some people develop lasting gut-brain disorders after acute gastroenteritis, linking infections to chronic digestive and psychological symptoms.

news OB/GYN & Women’s Health Public Health

Brazil’s Maternal Mortality Ratio May Be Substantially Higher Than Official Reports Because of Death Certificate Coding Errors

By MedXY 06/10/2026

A national Brazilian analysis found 3,480 maternal deaths were missed by official coding from 2010 to 2021, raising the median maternal mortality ratio from 58.2 to 67.5 per 100,000 live births.

Gastroenterology Infectious Diseases news

HBsAg Seroclearance Lowers Hepatocellular Carcinoma Risk Beyond Viral Suppression in Cirrhosis, but Does Not Reduce Hepatic Decompensation

By MedXY 06/10/2026

In NA-treated cirrhotic chronic hepatitis B with complete viral suppression, HBsAg seroclearance was linked to lower HCC risk but not lower hepatic decompensation, reinforcing functional cure as a meaningful but incomplete clinical endpoint.

Allergy & Immunology Gastroenterology news

Colonic GPR15L Emerges as a Microbiota-Shaping Host-Defense Peptide That Protects Against Experimental Colitis

By MedXY 06/10/2026

New data identify GPR15L as an epithelial host-defense peptide that reshapes the colonic microbiota, reduces experimental colitis, and may have therapeutic relevance in inflammatory bowel disease.

Diabetes & Endocrinology Gastroenterology news

An Obesity Subphenotype With Low Endogenous GLP-1 Production Shows Markedly Greater Weight Loss With Tirzepatide

By MedXY 06/10/2026

A 2026 study identifies a biologically distinct obesity subphenotype marked by fast gastric emptying, low GLP-1 synthesis, and substantially greater 6-month weight loss with tirzepatide.

Cardiology Neurology news

Acute Cardiac CT Added to Stroke Imaging Detects Cardiac Thrombi in About 1 in 16 Patients and Outperforms Transthoracic Echocardiography

By MedXY 06/10/2026

In a 3919-patient individual-level meta-analysis, acute cardiac CT detected cardiac thrombi in 6.2% of ischemic stroke cases, exceeded transthoracic echocardiography yield, added modest imaging burden, and identified patients with worse 90-day outcomes.

Neurology news Public Health

Why Prevalence Is Rising Differently in Parkinson Disease, Multiple Sclerosis, and Motor Neuron Diseases

By MedXY 06/09/2026

A large Sweden-France analysis suggests rising MS prevalence is mainly survival-driven, increasing MND prevalence reflects growing incidence, and PD prevalence rises modestly through mixed demographic and survival effects.

Neurology news Radiology

Mechanical Thrombectomy and Final Infarct Volume in Medium or Distal Vessel Occlusion Stroke: A Post Hoc Analysis of a Randomized Clinical Trial

By MedXY 06/09/2026

In a post hoc analysis of the DISTAL trial, mechanical thrombectomy plus best medical treatment preserved more threatened brain tissue than medical treatment alone in medium or distal vessel occlusion stroke, and better tissue preservation was linked to improved 90-day outcomes.

Diabetes & Endocrinology news Psychiatry

Biochemical Control Is Not Enough: Why Acromegaly Still Carries Major Quality-of-Life and Treatment Burden

By MedXY 06/09/2026

A 2026 review shows that many patients with acromegaly remain symptomatic and functionally impaired despite biochemical control, underscoring the need for routine patient-reported outcomes and lower-burden, multidisciplinary care.

Diabetes & Endocrinology news Public Health

Early 15% Weight Loss After Type 2 Diabetes Diagnosis Linked to Lower Complication Risk

By MedXY 06/09/2026

In a large U.K. cohort, losing at least 15% of body weight within 2 years of type 2 diabetes diagnosis was linked to lower risks of heart, kidney, and eye complications, along with better glucose and blood pressure control.

Cardiology Internal Medicine news

More ANOCA Endotypes, More Angina: Comprehensive Coronary Function Testing Reveals a Graded Symptom Burden

By MedXY 06/09/2026

In patients with ANOCA, overlapping coronary endotypes were common, and each additional abnormality identified on comprehensive coronary function testing was associated with significantly worse angina burden.

Cardiology Nephrology news

Finerenone May Lower Sudden Death Risk Across the Cardio-Kidney-Metabolic Continuum

By MedXY 06/09/2026

A prespecified pooled analysis of 18,991 participants found finerenone was associated with a significant reduction in sudden death across chronic kidney disease, type 2 diabetes, and heart failure populations.

Cardiology Internal Medicine news

SRPK3-Driven TPM1 Splicing Emerges as a Myofilament Mechanism of Diastolic Dysfunction in HFpEF

By MedXY 06/09/2026

A Circulation study identifies SRPK3-mediated alternative splicing of TPM1 exon 9a as a driver of myofibrillar disarray, reduced myocardial compliance, and diastolic dysfunction in HFpEF, highlighting a potential disease-modifying therapeutic target.

news Oncology Public Health

Impact of Population-Based Pathogenic Variant Testing on Risk-Based Breast Screening Recommendations: A Secondary Analysis of the WISDOM Study

By MedXY 06/09/2026

This WISDOM Study analysis found that most women with breast cancer pathogenic variants would not have been flagged for high-risk screening by clinical or polygenic risk models alone, supporting population-based genetic testing.

news Plastic Surgery Public Health

Millions of Americans Still Live Beyond Timely Reach of Registered Replantation Centers

By MedXY 06/09/2026

A U.S. geospatial analysis found major state-level disparities in access to registered hand trauma centers, with 13.3% of the population outside a 6-hour catchment and 7.6% still uncovered at 12 hours.

news Psychiatry

Serial Dependence in Working Memory Distinguishes Schizophrenia From Bipolar Disorder With Psychosis

By MedXY 06/09/2026

A multisite case-control study found repulsive serial bias in schizophrenia, attractive bias in healthy controls, and mixed patterns in bipolar disorder, supporting serial dependence as a potential cognitive biomarker across the psychosis spectrum.