artificial intelligence

Decoding Liver Fibrosis in MASLD: AI-Derived Collagen Phenotypes Enhance Molecular and Clinical Insights

By MedXY 06/25/2026

This article explores a novel AI framework that identifies distinct collagen deposition patterns in MASLD, offering improved molecular specificity and prognostic value beyond traditional fibrosis assessments.

Medical News news Public Health

The Sieve of Asclepius: A History of Navigating the Medical Literature, From Index to Algorithm

By MedXY 06/09/2026

A historically grounded review of how physicians, librarians, publishers, and now algorithms have filtered the expanding medical literature, shaping what counts as visible, credible, and clinically actionable knowledge.

AI news Oncology

AI Model Shows Moderate Accuracy for Predicting Complete Response After Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer

By MedXY 06/08/2026

A fine-tuned ensemble of tabular foundation models moderately predicted pathological complete response after TNT and showed potential to support watch-and-wait selection after recalibration.

news Radiology Respiratory

A Chest X-Ray AI Age Gap May Flag Early Spirometric Decline Before Overt Lung Disease

By MedXY 06/06/2026

In a large Korean health-screening cohort, chest radiograph-derived age acceleration was associated with both prevalent and incident PRISm and obstructive lung disease, supporting chest X-ray AI as a potential opportunistic marker of early pulmonary dysfunction.

Diabetes & Endocrinology news Radiology

AI-Driven Insights into Incidental Thyroid Findings: Prevalence, Clinical Impact, and the Overdiagnosis Dilemma

By MedXY 04/29/2026

A retrospective cohort study using AI to analyze radiology reports reveals high prevalence of incidental thyroid findings, strong association with diagnostic cascades, and potential overdiagnosis of low-risk thyroid cancers.

AI Family Medicine & Nutrition news

AI vs. Human Clinicians: Study Reveals Gaps in AI-Generated Clinical Notes

By MedXY 04/21/2026

A cross-sectional evaluation of AI-generated clinical notes found significant quality deficits compared to human-produced notes, particularly in thoroughness, organization, and usefulness.

Cardiology news

AI-Enhanced ECG Screening Pinpoints Atrial Fibrillation Risk in Older Adults: Key Insights from VITAL-AF Trial

By MedXY 04/15/2026

A VITAL-AF trial analysis reveals that combining ECG-based artificial intelligence with clinical risk scores significantly improves atrial fibrillation screening efficiency. The study demonstrates that high-risk individuals benefit most from screening, with those in the top CH-AI risk decile showing a number-needed-to-screen of just 43 per year.

news Oncology

Beyond Simple Quantification: How AI and Tumor-Stroma Ratio Are Redefining Prognosis Prediction in Hepatocellular Carcinoma

By MedXY 04/09/2026

Researchers have developed an AI-powered framework that uncovers a non-linear relationship between tumor-stroma ratio and mortality in hepatocellular carcinoma, using a novel token-guided multimodal fusion approach to improve prognostic accuracy beyond traditional methods.

AI Cardiology news

Adaptive AI Transforms Cardiovascular Event Adjudication: New Algorithm Achieves Near-Human Accuracy Across Multiple Endpoints

By MedXY 04/05/2026

Researchers developed and validated ADAPT-CEC, an artificial intelligence algorithm that can adjudicate cardiovascular events across different trial definitions. A hybrid approach combining AI with selective human review achieved 95.6% accuracy and replicated major trial results.

Clinical Updates Gastroenterology news

Artificial Intelligence in Gastric Endoscopy: Decoding the Findings of a Landmark Multicenter Randomized Controlled Trial

By MedXY 03/10/2026

A large-scale multicenter RCT investigating AI-assisted gastric neoplasm detection found no significant improvement in pathologically confirmed detection rates but demonstrated significant reductions in procedural blind spots and benefits for less experienced endoscopists.

AI Cardiology Clinical Updates news

Precision Prediction of Incident Heart Failure: The Clinical Integration of AI-Enabled Electrocardiography

By MedXY 03/09/2026

This review evaluates the breakthrough ECG2HF model, a publicly available AI tool that outperforms standard clinical scores in predicting 10-year heart failure risk using 12-lead ECG waveforms.

AI news Ophthalmology

Breaking the Hardware Barrier: How Domain-Shift AI Enables Vendor-Agnostic 3D OCT Macular Disease Detection

By MedXY 02/27/2026

A multicenter study in JAMA Ophthalmology introduces a deep learning model using domain-shift technology to accurately detect macular diseases across different OCT hardware vendors, achieving high negative predictive value and establishing a robust triage system for diverse clinical settings.

AI news Radiology

AI-Supported Mammography Outperforms Standard Double Reading: Insights from the MASAI Trial

By MedXY 02/25/2026

The MASAI trial demonstrates that AI-supported mammography screening achieves higher sensitivity and non-inferior interval cancer rates compared to standard double reading, while maintaining specificity and significantly reducing radiologist workload.

AI Cardiology news

AI-Enabled Stethoscopes in Primary Care: Why Implementation Science Matters More Than Algorithm Accuracy

By MedXY 02/25/2026

The TRICORDER trial demonstrates that while AI stethoscopes are capable of detecting heart failure, atrial fibrillation, and valvular disease, their real-world implementation in UK primary care did not yield a statistically significant increase in new diagnoses over 12 months.

AI news Ophthalmology

Human-AI Collaboration Enhances Clinical Reasoning in Ophthalmology but Risks Overconfidence and Automation Bias

By MedXY 02/22/2026

A crossover study involving 30 ophthalmologists and trainees reveals that while Claude-3.5-Sonnet collaboration improves diagnostic accuracy in complex cases, it also increases confidence in incorrect decisions and fails to reach the performance of the AI alone.

AI news

AI Assistant Achieves High Accuracy in Molecular-Based CNS Tumor Classification: A Multi-Institutional Validation

By MedXY 02/18/2026

This multi-institutional study validates Neuropath-AI, a deep-learning system that predicts CNS tumor types by inferring molecular features from histopathology slides. Achieving 80% top-1 accuracy in high-confidence samples, the model offers a scalable tool for enhancing diagnostic precision in neuro-oncology.

AI news Oncology

AI-Driven Detection of Extranodal Extension Outperforms Radiologists in Predicting Outcomes for HPV-Positive Oropharyngeal Cancer

By MedXY 02/11/2026

A single-center study demonstrates that an AI pipeline for CT-based lymph node segmentation and extranodal extension classification significantly improves prognostic accuracy for HPV-positive oropharyngeal cancer compared to traditional radiological assessment, identifying high-risk patients more effectively.

AI news Psychiatry

High Empathy, Low Accuracy: Can Generative AI Safely Navigate Alcohol Misuse Support?

By MedXY 02/02/2026

A longitudinal study published in NEJM AI evaluates seven generative AI chatbots for alcohol misuse support, finding that while they excel in empathy and non-judgmental language, they frequently provide low-quality or inaccurate medical information, highlighting critical safety concerns for clinical application.

AI Cardiology news

AI-ECG Models for Heart Failure Screening Show High Accuracy in First-of-its-Kind Independent Comparison Study

By MedXY 01/26/2026

This independent validation study confirms that AI-enhanced ECG models effectively detect left ventricular systolic dysfunction across diverse populations, achieving AUROCs up to 0.93. However, significant barriers remain regarding model transparency and data sharing for clinical implementation.

AI Infectious Diseases news

AI-Driven Decision Support for Antibiotic Switching: Why Clinicians Value Caution Over Speed

By MedXY 01/15/2026

A randomized multimethod study reveals that while AI clinical decision support systems for antibiotic switching are well-received, their primary influence is reinforcing conservative prescribing. The study underscores that usability and clinical evidence outweigh the importance of AI explanations at the point of care.