Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT

Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT

A pilot randomized trial comparing targeted temperature management at 35°C versus normothermia in intubated heatstroke patients showed no survival or neurological benefit from hypothermia but increased gastrointestinal injury and arrhythmias, highlighting safety concerns and questioning routine hypothermia use in this setting.
High-Dose Rocuronium Enhances First-Attempt Intubation Success in Critically Ill ICU Patients: Insights from Secondary Analysis of Multicenter Trials

High-Dose Rocuronium Enhances First-Attempt Intubation Success in Critically Ill ICU Patients: Insights from Secondary Analysis of Multicenter Trials

Secondary analysis of two multicenter trials reveals that high-dose rocuronium (>1.2 mg/kg) improves first-attempt intubation success in ICU patients but not in the emergency department, highlighting a potential dose-dependent effect on airway management outcomes.