Anesthesiology – Medxy AI

Awake Intubation in Emergency Settings: Incidence, Techniques, and Outcomes from a Decade of Airway Registries

By MedXY 07/21/2026

This study examines emergency physician-performed awake intubations over 10 years, highlighting a 7.2% incidence, high success rates (92%), and low adverse events in a tertiary emergency department.

Anesthesiology Clinical Updates news

WAFER Trial and Beyond: Comparative Efficacy and Pragmatic Implications of WALANT versus General and Regional Anesthesia in Flexor Tendon Repair

By MedXY 07/12/2026

This review synthesizes evidence from the WAFER trial and related studies comparing WALANT to GA/RA in flexor tendon repair, highlighting functional outcomes, safety, cost-effectiveness, and patient-centered benefits including earlier return to work.

Anesthesiology Clinical Updates news Public Health

Patient-Centered Prescription Opioid Tapering: Evidence from a Multisite Randomized Clinical Trial and Complementary Digital Interventions

By MedXY 07/12/2026

A large RCT found that adding behavioral therapies to patient-centered opioid tapering did not improve taper success at 12 months, though CBT may reduce adverse effects; complementary digital support programs show feasibility but require further validation.

Anesthesiology news Otorhinolaryngology

Innovative Orocannula: A 3D-Printed Transoral Device for Safe Respiratory Monitoring During Sedation

By MedXY 07/11/2026

A novel 3D-printed transoral airway device, the Orocannula, provides reliable oxygen delivery and CO2 monitoring during sedation with high retention and minimal flow obstruction, potentially improving patient safety during procedural sedation.

Anesthesiology Critical Care news

Optimizing Intraoperative Blood Pressure in Hypertensive High-Risk Patients: Insights from the HISTAP Trial

By MedXY 07/09/2026

In hypertensive high-risk patients undergoing major abdominal surgery, targeting an intraoperative mean arterial pressure ≥80 mmHg reduces postoperative organ dysfunction and acute kidney injury compared to the standard target of ≥65 mmHg.

Anesthesiology news Psychiatry

Decoding Ketamine’s Neurophysiology Under General Anesthesia: Insights for Targeted Therapeutics

By MedXY 06/26/2026

This study reveals that general anesthesia selectively modulates ketamine-induced EEG changes, preserving beta-gamma oscillations while attenuating theta augmentation, highlighting discrete neurophysiologic components underlying ketamine's effects and informing targeted therapeutic development.

Anesthesiology Critical Care news

A New Bedside Twist on Passive Leg Raising: PPV Change Predicts Fluid Responsiveness During Pressure Support Ventilation

By MedXY 06/15/2026

In PSV patients, passive leg raising–induced PPV change predicted preload responsiveness, especially when inspiratory effort was low by P0.1.

Anesthesiology Clinical Updates news OB/GYN & Women's Health

Optimizing Postpartum Pain Management: Addressing Hospital Variation in Opioid Prescribing Following Vaginal Birth and Associated Procedures

By MedXY 06/04/2026

This review analyzes significant inter-hospital variations in opioid prescribing for vaginal births with complications, highlighting the need for standardized postdischarge pain management protocols to reduce unnecessary opioid exposure.

Anesthesiology General Surgery news

What the New Thyroid Surgery Consensus Means for Same-Day Care

By MedXY 05/31/2026

The American Thyroid Association’s updated consensus refines who can safely undergo outpatient thyroid surgery and what teams must do before, during, and after the operation to reduce complications.

Anesthesiology news Ophthalmology

Anesthesia-Related Neurologic Risk in Patients of Venezuelan Descent: Implications for Ophthalmology

By MedXY 05/21/2026

A rare, severe neurologic complication has been linked to general anesthesia in patients of maternal Venezuelan descent. Ophthalmologists should screen for ancestry and family history, involve anesthesiology early, and consider genetic evaluation before elective surgery.

Anesthesiology news Public Health

Geographic Disparities in Opioid Prescribing Patterns for Toothache Pain in the United States

By MedXY 04/27/2026

A national study reveals significant state-level and urban-rural variations in opioid prescribing following toothache diagnoses, with 15 states exceeding the national average and rural areas showing slightly lower prescription rates.

Anesthesiology news Otorhinolaryngology

RAI Outperforms mFI-5 in Predicting Post-UPPP Complications: A Frailty Stratification Breakthrough

By MedXY 04/23/2026

The Risk Analysis Index (RAI) significantly outperforms the modified frailty index-5 (mFI-5) in predicting mortality and major complications after uvulopalatopharyngoplasty, supporting its adoption for preoperative risk assessment in sleep surgery.

Anesthesiology Critical Care news

Remimazolam Besylate Matches Propofol for Short-Term ICU Sedation: The SHOSREB Trial

By MedXY 04/13/2026

The SHOSREB trial demonstrates that remimazolam besylate is non-inferior to propofol for short-term light sedation in mechanically ventilated ICU patients, with both agents achieving 97.5% successful sedation rates and comparable time within target RASS scores.

Anesthesiology Neurology news

The Hidden Driver of Chronic Pain: How Macrophages Fuel Neuropathic Symptoms

By MedXY 03/27/2026

Researchers using human stem cell models have discovered that macrophages actively amplify the electrical signals of damaged nerves, driving the spontaneous pain characteristic of neuropathy, offering a new target for non-opioid pain relief.

Anesthesiology General Surgery news

Wearable TEAS Outperforms Metoclopramide in Managing Moderate to Severe Postoperative Nausea and Vomiting

By MedXY 03/23/2026

A randomized clinical trial demonstrates that wearable Transcutaneous Electrical Acupoint Stimulation (TEAS) provides superior 2-hour remission and significantly lower 24-hour relapse rates compared to intravenous metoclopramide for moderate to severe PONV in high-risk surgical patients.

Anesthesiology Neurology news

Neuro-Immune Crosstalk: Macrophages Directly Amplify Spontaneous Activity in Damaged Human Sensory Neurons

By MedXY 03/22/2026

A groundbreaking human iPSC-derived co-culture study reveals that macrophages respond to neuronal injury by adopting a pro-algesic state, directly intensifying spontaneous neuronal firing—a key driver of chronic neuropathic pain and a novel target for future analgesics.

Anesthesiology news

Epidural Anesthesia Outperforms IV Remifentanil in External Cephalic Version: Results from a Large-Scale Cohort Study

By MedXY 03/13/2026

A large prospective cohort study reveals that epidural anesthesia significantly increases the success rate of external cephalic version (70.0%) and subsequent vaginal delivery (72.2%) compared to intravenous remifentanil, despite a higher incidence of manageable procedural complications.

Anesthesiology news Orthopedics

Precision Medicine Fails to Improve Postoperative Pain: Insights from the CYP2D6-Guided Opioid Trial

By MedXY 02/23/2026

A randomized clinical trial demonstrates that while CYP2D6 genotyping significantly shifts opioid prescribing patterns for poor and intermediate metabolizers, it does not improve pain control or reduce opioid consumption within the context of modern multimodal postoperative care.

Anesthesiology General Surgery news

High-Risk Surgery Significantly Impairs Restorative Sleep: A Wearable Technology Analysis

By MedXY 02/05/2026

This cohort study demonstrates that postoperative sleep architecture is differentially disrupted based on surgical risk. High-risk procedures cause prolonged deficits in REM and deep sleep, which are associated with increased complications, suggesting that sleep monitoring could be a vital component of postoperative care.

Anesthesiology General Surgery news

Wearable TEAS Device Outperforms Metoclopramide for Moderate to Severe Postoperative Nausea and Vomiting

By MedXY 01/31/2026

A randomized clinical trial demonstrates that wearable transcutaneous electrical acupoint stimulation (TEAS) provides superior symptom relief and significantly lower relapse rates compared to intravenous metoclopramide in managing moderate to severe postoperative nausea and vomiting.