Assessing Survival Outcomes of Simultaneous Liver-Kidney Versus Liver Alone Transplantation in the Era of the 2017 OPTN Policy

Assessing Survival Outcomes of Simultaneous Liver-Kidney Versus Liver Alone Transplantation in the Era of the 2017 OPTN Policy

This analysis of over 63,000 US liver transplants reveals that simultaneous liver-kidney transplantation (SLKT) confers significant survival benefit only in patients with severe renal dysfunction (eGFR <30), with no advantage in those with better pretransplant kidney function. The 2017 OPTN policy reduced SLKT procedures without compromising survival, supporting stage-specific organ allocation and the 'Safety Net' approach.