Nephrology – Medxy AI

Balancing Blood Pressure After Endovascular Thrombectomy: Risks of Acute Kidney Injury and Impact on Stroke Recovery

By MedXY 07/31/2026

Intensive blood pressure lowering post-thrombectomy increases acute kidney injury risk, which correlates with poorer neurological outcomes in stroke patients. Careful BP management is crucial to prevent renal complications and optimize recovery.

Critical Care Nephrology news

STARDaki: Standardizing How We Report Acute Kidney Injury Biomarker Studies

By MedXY 07/30/2026

An expert consensus (STARDaki) extends STARD to improve reporting of diagnostic test accuracy studies for acute kidney injury (AKI), specifying patient selection, reference standards, timing, assay details and test-retest reliability.

Diabetes & Endocrinology Nephrology news

IgG N-Glycosylation Profiles as Predictive Biomarkers for Diabetic Nephropathy in Type 2 Diabetes: Insights from a Pooled Prospective Cohort Analysis

By MedXY 07/19/2026

A pooled analysis of four cohorts reveals that specific IgG N-glycosylation patterns are significantly associated with incident diabetic nephropathy, highlighting immune-related mechanisms in disease progression.

General Surgery Nephrology news

Expanding the Horizon of Simultaneous Liver-Kidney Transplantation: Leveraging DCD Donors with Machine Perfusion Technologies

By MedXY 07/08/2026

This nationwide US study analyzes 10,687 simultaneous liver-kidney transplants, highlighting increased use of DCD donors with machine perfusion and comparable outcomes to DBD transplants, supporting broader DCD adoption in selected patients.

Cardiology Nephrology news

Acoramidis and Kidney Function in Transthyretin Amyloid Cardiomyopathy: Clinical Implications and Hemodynamic Insights

By MedXY 07/03/2026

Acoramidis stabilizes transthyretin and shows kidney-protective effects in transthyretin amyloid cardiomyopathy by reducing eGFR decline and albuminuria, with an initial reversible dip in kidney function associated with improved clinical outcomes.

Diabetes & Endocrinology Nephrology news

Continuous Glucose Monitoring and Survival Benefits in Diabetic Veterans on Dialysis: Insights from a Nationwide Cohort

By MedXY 07/01/2026

Among U.S. veterans with diabetes on dialysis, continuous glucose monitoring (CGM) use was associated with significantly lower mortality risk compared to non-CGM use, highlighting CGM's potential to improve survival in this high-risk population.

Internal Medicine Nephrology news

The Impact of APOL1 Genotype on Kidney Function After Living Donation in Black Donors

By MedXY 06/30/2026

APOL1 high-risk genotypes significantly increase the risk of reduced kidney function after living kidney donation in Black donors, highlighting the need for genotype screening to improve donor risk stratification.

Diabetes & Endocrinology Nephrology news

Thyroid Hormones May Offer a New Therapeutic and Prognostic Angle in ADPKD

By MedXY 06/17/2026

Thyroid hormone signaling may influence ADPKD progression, with preclinical cyst suppression and patient biomarker associations suggesting prognostic and therapeutic potential.

Cardiology Nephrology news

Finerenone May Lower Sudden Death Risk Across the Cardio-Kidney-Metabolic Continuum

By MedXY 06/09/2026

A prespecified pooled analysis of 18,991 participants found finerenone was associated with a significant reduction in sudden death across chronic kidney disease, type 2 diabetes, and heart failure populations.

Gastroenterology Nephrology news

Chronic Kidney Disease Worsens Short-Term Outcomes in Hospitalized Patients With Cirrhosis Across a Global Cohort

By MedXY 06/07/2026

In a large international prospective cohort of hospitalized patients with cirrhosis, chronic kidney disease was common, clustered with metabolic risk, and strongly associated with acute kidney injury, more decompensation, and higher in-hospital and 30-day mortality.

Cardiology Nephrology news

Finerenone Shows Consistent Cardiovascular and Kidney Benefit Across CKM Syndrome Stages in Type 2 Diabetes and CKD

By MedXY 06/07/2026

A post hoc FIDELITY analysis suggests finerenone improves cardiovascular and kidney outcomes across CKM stages and may modestly shift patients toward CKM regression over time.

General Surgery Nephrology news

SLA-DR–Deleted Donor Pigs Show Durable Kidney Xenograft Function and a Favorable Safety Profile in Rhesus Monkeys

By MedXY 06/06/2026

CRISPR-engineered GGTA1/B4GALNT2/SLA-DR knockout pigs remained healthy, screened negative for 55 zoonotic pathogens, and supported long-term renal xenograft function in rhesus monkeys when preformed anti-SLA antibodies were absent.

Nephrology news Urology

Impact of Normothermic Regional Perfusion on Outcomes in Kidney Transplantation From Donors After Circulatory Death

By MedXY 06/04/2026

In a nationwide U.S. analysis of 21,010 adult DCD kidney transplants, normothermic regional perfusion lowered delayed graft function, shortened hospital stay, and improved graft and patient survival, with the greatest benefit in higher-risk donor and recipient groups.

Nephrology news OB/GYN & Women’s Health

Proteinuria in Preeclampsia and Long-Term Risk of Maternal Kidney and Cardiovascular Disease

By MedXY 05/26/2026

Higher proteinuria in preeclampsia was linked to greater long-term risk of maternal hypertension and chronic kidney disease, with overall increased risk of cardiovascular disease as well.

Diabetes & Endocrinology Nephrology news

Tirzepatide vs dulaglutide: kidney outcomes in type 2 diabetes from SURPASS-CVOT

By MedXY 05/12/2026

In a pre-specified exploratory analysis of SURPASS-CVOT, tirzepatide reduced major kidney events versus dulaglutide in people with type 2 diabetes and cardiovascular disease, mainly by lowering new macroalbuminuria and slowing eGFR decline.

Diabetes & Endocrinology Nephrology news

Visceral Fat Predicts Diabetic Kidney Disease Differently in Men and Women, With a High-Risk Signal in Leaner Men

By MedXY 05/03/2026

In a 93,532-person prospective diabetes cohort, visceral fat area independently predicted incident diabetic kidney disease, with striking sex- and BMI-specific patterns, including a U-shaped risk curve in men and elevated risk in low-VFA men.

Cardiology Nephrology news

Exploring the Link Between Cardiovascular-Kidney-Metabolic Syndrome and Heart Failure Risk in Older Adults

By MedXY 04/29/2026

Higher CKM syndrome stages correlate with adverse cardiac remodeling and increased heart failure risk in older adults, as shown in the ARIC Study.

Critical Care Nephrology news

Low-Calorie, Low-Protein Feeding in Shock: No Harm to Kidneys, NUTRIREA-3 Analysis Confirms

By MedXY 04/21/2026

Early low-calorie and low-protein nutrition in critically ill patients with shock does not worsen renal outcomes compared to standard feeding, per NUTRIREA-3 post hoc analysis.

Gastroenterology Nephrology news

OCE-205 Signals a Potential New Direction for Hepatorenal Syndrome-AKI, with Tolerability at the Center

By MedXY 04/20/2026

In a phase 2 randomized trial, OCE-205 improved HRS-AKI in more patients than placebo and showed no excess ischemic or respiratory toxicity, but the study was underpowered after early termination.

Diabetes & Endocrinology Nephrology news

Blood Pressure Variability Emerges as Independent Predictor of Kidney Disease Progression in Type 1 Diabetes, with African Caribbean Ethnicity as Key Risk Factor

By MedXY 04/05/2026

A 14-year cohort study of 3,079 individuals with type 1 diabetes reveals that visit-to-visit blood pressure variability, particularly systolic blood pressure variability measured by average real variability, significantly predicts diabetic kidney disease progression. African Caribbean ethnicity emerged as an independent risk factor, with a 54% increased hazard per unit increase in systolic BP variability.