older adults – Medxy AI

Cardiovascular Risks of CAR-T Therapy in Older Adults: Insights from US Medicare Data

By MedXY 09/19/2026

Among older adults receiving CAR-T therapy, 5.8% experienced major adverse cardiovascular events (MACE), associated with increased mortality. Pre-existing cardiac conditions heightened risk, underscoring the need for cardiovascular monitoring and preventive strategies.

Emergency Medicine General Surgery news

Rethinking Surgical Quality Metrics: The Role of Operative-to-Nonoperative Management Ratio in Elderly Emergency General Surgery Outcomes

By MedXY 09/15/2026

This study analyzes how the balance between operative and nonoperative management in emergency general surgery for older adults relates to their odds of discharge home, proposing ONR as a novel quality benchmark beyond traditional metrics.

Cardiology news Public Health

Unveiling the Cardiovascular Toll of Long-Term Wildfire Smoke PM2.5 Exposure in Older Americans

By MedXY 09/15/2026

Long-term cumulative exposure to wildfire smoke PM2.5 significantly increases cardiovascular hospitalizations among U.S. older adults, with notable risks in ischemic heart disease and arrhythmias, highlighting the need for targeted public health measures.

Diabetes & Endocrinology news

Improved Glycaemic Control and Vascular Outcomes After MiniMed 780G Usage in Older Adults with Type 1 Diabetes: A Randomised Controlled Trial

By MedXY 09/08/2026

This study demonstrates that using the MiniMed 780G hybrid closed-loop system significantly improves glycaemic management and shows a trend toward better microvascular function in adults aged 65 and above with type 1 diabetes, without increasing hypoglycaemia risk.

Critical Care Internal Medicine news

Post-ICU Frailty in Older Adults Following Septic Shock: Key Predictors and Clinical Implications

By MedXY 08/26/2026

This study identifies baseline frailty, organ dysfunction severity, and corticosteroid use as independent predictors of severe post-intensive care frailty in older septic shock survivors, highlighting critical factors for targeted post-ICU care.

Cardiology Internal Medicine news

Longitudinal Heart Stress Changes and Cardiovascular Risk in Older Adults: Insights from NT-proBNP Dynamics

By MedXY 08/20/2026

Changes in NT-proBNP levels over three years define heart stress status, which improves cardiovascular and mortality risk prediction in older adults without prior CVD, underscoring its utility in clinical risk stratification.

Internal Medicine Neurology news

Deciphering the Link Between Postoperative Delirium, Rehospitalization, and Cognitive Decline in Older Adults

By MedXY 08/10/2026

This study investigates whether recurrent hospitalizations mediate the association of postoperative delirium with long-term cognitive decline in seniors after major surgery, finding that rehospitalization does not significantly affect this relationship.

Internal Medicine news Public Health

Predicting Opioid Use Disorder and Overdose Risk in Older Adults: Evaluating Prognostic Models

By MedXY 07/21/2026

This study develops and compares predictive models incorporating claims and patient-reported data to forecast time to first opioid use disorder (OUD) or overdose (OD) among older adults with chronic pain on opioids, identifying key risk factors for early intervention.

Clinical Updates news Respiratory

Real-world Effectiveness of Adjuvanted RSVPreF3 Vaccine in Preventing RSV-Related Hospitalization Among US Adults Aged ≥60 Years: A Comprehensive Review

By MedXY 07/20/2026

This review synthesizes current evidence on the effectiveness of adjuvanted RSVPreF3 vaccination in reducing RSV-related hospitalizations among older US adults, highlighting substantial protection across high-risk subgroups.

Gastroenterology Internal Medicine news

Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population

By MedXY 07/17/2026

Older adults with MASLD, especially those aged 75 and above, experience a high burden of polypharmacy linked to multimorbidity, necessitating careful medication management to balance disease control and geriatric vulnerabilities.

Cardiology news

Unveiling the Burden of Valvular Heart Disease Among Older Americans: Insights from the PREVUE-VALVE Study

By MedXY 06/26/2026

The PREVUE-VALVE study reveals a significant prevalence of moderate or greater valvular heart disease among U.S. adults aged 65-85, highlighting substantial public health implications and the value of decentralized echocardiographic screening.

news Orthopedics Public Health

Can Prehabilitation Reduce Complications After Spinal Fusion in Older Adults? What a New Randomized Trial Suggests

By MedXY 06/19/2026

A multicenter randomized trial found that 4-week multimodal prehabilitation added to ERAS reduced 90-day complications after spinal fusion in adults aged 75 years or older.

Hematology-Oncology Internal Medicine news

Allogeneic Stem Cell Transplantation After 70: Japanese Registry Data Define Who May Benefit Most

By MedXY 06/19/2026

A Japanese registry study of 929 patients aged 70+ identified six predictors of worse survival after allo-HSCT and created a simple score that sharply stratified 2-year overall survival from 57.1% to 2.5%.

Cardiology news Public Health

Low-Level Airborne Particulate Matter and Risk of Hypertension Hospitalization in Older U.S. Adults

By MedXY 06/10/2026

A large U.S. study found that even PM2.5 levels below current federal standards were linked to higher hypertension hospitalization risk in older adults, especially among women and some regional and socioeconomic groups.

Cardiology news Public Health

Low-Level Airborne Particulate Matter and Risk of Hypertension Hospitalization in Older U.S. Adults

By MedXY 06/10/2026

Among more than 26 million older U.S. adults, even PM2.5 levels below current standards were linked to higher hypertension hospitalization risk, suggesting no clearly safe low-exposure threshold.

Emergency Medicine Internal Medicine news

One in Six Older Emergency Department Patients Has Delirium: New Multisite Data Highlight Missed Risk, Mixed Management, and Higher Hospital Use

By MedXY 06/04/2026

A large multisite cohort found delirium in 16% of older adults in the emergency department, including nearly 8% of those discharged, with strong links to dementia, acuity, hospitalization, and 30-day readmission.

Emergency Medicine Internal Medicine news

One in Six Older Adults Presenting to the Emergency Department Had Delirium, With Higher Admission and 30-Day Readmission Risk

By MedXY 06/04/2026

A large multi-site cohort found delirium in 16% of older ED patients, including many discharged home, and linked it to higher admission and 30-day readmission, underscoring the need for standardized screening and supportive care.

news Ophthalmology Public Health

A Clinically Relevant Threshold of Impaired Contrast Sensitivity Among Older US Adults

By MedXY 06/04/2026

A large U.S. study found that a contrast sensitivity score of 1.60 logCS marks the point where older adults are more likely to experience everyday vision disability, even when standard visual acuity may seem acceptable.

Neurology news Public Health

Cerebral “Dirty-Appearing” White Matter and Its Link to Cognitive Decline and Dementia Risk

By MedXY 05/13/2026

In older adults with limited small vessel disease, “dirty-appearing” white matter on MRI was not linked to baseline cognition, cognitive decline, or dementia risk, unlike conventional white matter hyperintensities.

news Oncology Public Health

Rates of Systemic Treatment for Metastatic Non-Small Cell Lung Cancer Among Older Adults

By MedXY 05/12/2026

A population-based study of older adults with metastatic NSCLC found that fewer than half received systemic treatment, with only slight improvement over time. Oncology referral and biomarker testing were strongly linked to treatment, while advanced age and barriers to care lowered access.