news – Page 4 – Medxy AI

高风险腹部手术中以心脏指数为导向的血流动力学治疗：来自 PELICAN 试验的启示

Evaluating Cardiac Index-Guided Hemodynamic Therapy in High-Risk Abdominal Surgery: Insights from the PELICAN Trial

By MedXY 10/26/2026

The PELICAN trial found that individualized cardiac index-guided intraoperative hemodynamic therapy did not reduce major postoperative complications compared to routine care in high-risk major abdominal surgery patients.

Neurology news Pediatrics

Remote Aerobic Exercise Accelerates Recovery in Youth with Prolonged Concussion: Insights from the MSTEP Randomized Trial

By MedXY 10/26/2026

A virtual aerobic exercise program significantly improves recovery speed and quality of life in youth with prolonged concussion, especially when initiated within three months of injury, outperforming stretching interventions.

类风湿关节炎中JAK 抑制剂减量与标准剂量的比较：基于倾向评分匹配的真实世界研究洞见

news Rheumatology

Evaluating Reduced Versus Standard Dosing of Janus Kinase Inhibitors in Rheumatoid Arthritis: Insights from a Propensity Score-Matched Real-World Study

By MedXY 10/26/2026

A real-world Japanese study finds comparable 24-month treatment persistence between reduced and standard dosing of JAK inhibitors in rheumatoid arthritis patients with preserved renal function, with dose considerations influenced by poor prognostic factors and renal status.

Internal Medicine Nephrology news

Optimizing Early Mycophenolate Mofetil Dosing Post-Kidney Transplant: A Nomogram Integrating Triglycerides and Body Weight

By MedXY 10/26/2026

A novel nomogram using pretransplant triglycerides and body weight shows promise to guide early mycophenolate mofetil dosing after kidney transplantation, potentially reducing drug overexposure before therapeutic drug monitoring is feasible.

Dermatology news Pediatrics

International Consensus on Low‑Dose Oral Minoxidil in Children: Practical, Pediatric‑Specific Guidance

By MedXY 10/26/2026

An international expert consensus provides the first pediatric‑specific framework for low‑dose oral minoxidil (LDOM) in children aged 4–11 years: indications, dosing strategies, safety checks, monitoring, contraindications, and long‑term use.

news Oncology Plastic Surgery

Innovative Oncoplastic Breast Reconstruction: Efficacy and Versatility of J-Scar Mammaplasty

By MedXY 10/26/2026

J-scar mammaplasty offers a safe, versatile level 2 oncoplastic technique with favorable aesthetic and oncologic outcomes, validated in a 157-patient study with low complication rates and high satisfaction.

Critical Care Neurology news

Differential Ventilatory Strategies and Outcomes in Neurocritical Versus Non-Neurocritical Care Patients: Insights From the PRIME Database

By MedXY 10/26/2026

A pooled analysis from the PRIME database reveals distinct ventilatory management patterns and ARDS incidence in neurocritical versus non-neurocritical patients, highlighting key associations between ventilator settings and outcomes.

患者中心の医師コミュニケーションは心血管代謝疾患のセルフマネジメントを促進するのか？――全国調査

Cardiology Diabetes & Endocrinology news

Does Patient-Centered Communication by Physicians Facilitate Cardiometabolic Disease Self-management Among Community Health Center Patients? A Nationwide Study

By MedXY 10/26/2026

This study examines how effective patient-centered communication by physicians at community health centers supports self-management behaviors in patients with cardiometabolic conditions.

靶向线粒体复合体I亚基NDUFS2：提升FLT3-ITD急性髓系白血病对FLT3抑制剂的疗效

Hematology-Oncology news

Enhancing FLT3 Inhibitor Efficacy in FLT3-ITD AML Through Targeting Mitochondrial Complex I Subunit NDUFS2

By MedXY 10/26/2026

Targeting the mitochondrial complex I subunit NDUFS2 enhances sensitivity to FLT3 inhibitors and overcomes drug resistance in acute myeloid leukemia with FLT3-ITD mutations, suggesting a promising therapeutic strategy.

Clinical Updates news Respiratory

Striving for Equity in Cystic Fibrosis Research: Perspectives from Black and Hispanic/Latino(a) Individuals with CF

By MedXY 10/26/2026

This review explores barriers and facilitators influencing research participation among Black and Hispanic/Latino(a) individuals with cystic fibrosis (CF), highlighting systemic inequities, racialized experiences, and community-centered solutions to improve trial inclusivity.

news Ophthalmology Otorhinolaryngology

Uncovering Novel Genetic Contributors to Usher Syndrome: Insights from Comprehensive Mouse Knockout Models

By MedXY 10/26/2026

A large-scale phenotypic screen of 9,139 knockout mouse lines identified 18 candidate genes linked to retinal and hearing abnormalities, offering promising new targets for understanding and diagnosing Usher syndrome.

news Otorhinolaryngology

Enhancing Nasal Septal Perforation Repair: The Role of Contralateral Free Mucosal Grafting for Rapid Re-Epithelialization

By MedXY 10/26/2026

Free mucosal grafting on the contralateral side during nasal septal perforation repair enhances healing, achieving over 90% anatomical closure with rapid re-epithelialization and improved nasal symptoms.

Gastroenterology General Surgery news

Unveiling the Microbiome Landscape of Anastomotic Leaks After Foregut Surgery: Implications for Management and Outcomes

By MedXY 10/26/2026

This study explores how microbiome compositions differ in patients with foregut anastomotic leaks managed endoscopically versus surgically, highlighting nutrition and microbial patterns as key factors influencing healing.

Diabetes & Endocrinology news OB/GYN & Women's Health

Unraveling the Complex Interplay of BMI and Inflammation on Assisted Reproductive Outcomes in PCOS Women

By MedXY 10/26/2026

This study reveals bidirectional mediation between BMI and inflammatory markers affecting embryo quality and availability in PCOS women undergoing ART, highlighting BMI's predominant role.

Neurology news

Disparities in Utilization and Adherence to Antiamyloid Therapies in Alzheimer’s Disease and Mild Cognitive Impairment

By MedXY 10/26/2026

This study reveals that younger, non-Hispanic White patients with fewer comorbidities and lower socioeconomic vulnerability are more likely to receive antiamyloid medications for Alzheimer’s, while higher comorbidity predicts lower initial adherence.

news Oncology Otorhinolaryngology

Optimizing Neck Radiation in Advanced Differentiated Thyroid Carcinoma: Balancing Locoregional Control and Toxicity through Field Reduction

By MedXY 10/26/2026

This study demonstrates that reducing radiation fields in advanced differentiated thyroid carcinoma lowers toxicity without compromising locoregional tumor control, supporting personalized radiotherapy strategies.

Clinical Updates news Orthopedics

Quadriceps Strength Recovery Trajectories Following ACL Reconstruction: Associations with Preoperative Predictors but Not Clinical Outcomes

By MedXY 10/26/2026

Quadriceps strength recovery after ACL reconstruction exhibits three distinct trajectories linked to preoperative strength and meniscectomy status, yet these trajectories do not correlate with postoperative clinical outcomes at one year.

Neurology news Public Health

Enhancing Post-Stroke Physical Activity Through Telehealth and Wearable Technology: A Feasibility Randomised Controlled Trial

By MedXY 10/25/2026

A feasibility RCT demonstrates that a telehealth-delivered behaviour change intervention, augmented with a physical activity monitor, can increase physical activity in post-stroke individuals, supporting future large-scale trials.

Dentistry news

Advancing Dental Education: Repair Versus Replacement of Defective Composite Restorations in Canadian Dental Schools

By MedXY 10/25/2026

A comprehensive assessment of the teaching practices regarding repair and replacement of defective composite restorations in Canadian dental schools highlights the move towards minimally invasive dentistry and calls for harmonization of educational standards.

幼儿17DD黄热病疫苗分剂量接种的免疫原性与安全性：乌干达Ⅳ期随机试验及更广泛证据

Clinical Updates news Public Health

Immunogenicity and Safety of Fractional 17DD Yellow Fever Vaccine Doses in Young Children: Evidence from a Phase 4 Randomised Trial in Uganda and Broader Context

By MedXY 10/25/2026

Fractional doses (one-fifth and one-half) of 17DD yellow fever vaccine demonstrate non-inferior immunogenicity and comparable safety to full doses in children aged 9–23 months, supporting dose-sparing strategies during vaccine shortages.