Vibration-Controlled Transient Elastography vs. Liver Histology: Head-to-Head Prognostic Comparison in Metabolic Dysfunction-Associated Steatotic Liver Disease
Posted inGastroenterology Internal Medicine news

Vibration-Controlled Transient Elastography vs. Liver Histology: Head-to-Head Prognostic Comparison in Metabolic Dysfunction-Associated Steatotic Liver Disease

This study demonstrates that vibration-controlled transient elastography offers prognostic accuracy comparable to liver histology for predicting liver-related events in MASLD, supporting its role as a noninvasive alternative in clinical practice and trials.
Functional Anti-preS1 Antibody Responses and Their Role in Viral Control in Chronic Hepatitis B
Posted inClinical Updates Gastroenterology Infectious Diseases news

Functional Anti-preS1 Antibody Responses and Their Role in Viral Control in Chronic Hepatitis B

This review synthesizes evidence on preS1 antigen and anti-preS1 IgG dynamics in chronic hepatitis B, highlighting their correlations with viral replication, liver inflammation, and functional cure, and elucidates the neutralising potential of anti-preS1 antibodies as markers of endogenous viral control.
Preservation of Islet Function and Glycaemic Control After Total Pancreatectomy with Islet Autotransplantation: Insights From Continuous Glucose Monitoring
Posted inDiabetes & Endocrinology Gastroenterology news

Preservation of Islet Function and Glycaemic Control After Total Pancreatectomy with Islet Autotransplantation: Insights From Continuous Glucose Monitoring

This study demonstrates that nearly half of islet secretory function is preserved following total pancreatectomy with islet autotransplantation (TPIAT), independent of preoperative glycaemic status or prior pancreatic surgery. Continuous glucose monitoring reveals meaningful correlations between islet function and glycaemic control post-TPIAT.
Fecal Calprotectin as a Biomarker for Diagnosis and Monitoring of Gastrointestinal Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation
Posted inClinical Updates Gastroenterology Hematology-Oncology news

Fecal Calprotectin as a Biomarker for Diagnosis and Monitoring of Gastrointestinal Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Fecal calprotectin offers a non-invasive, dynamic biomarker to predict, diagnose, and monitor GI-GVHD post-allo-HSCT, correlating with endoscopic severity and treatment response, but requires integrated clinical interpretation due to limited specificity.
Advancing Donation After Circulatory Death Liver Transplantation: National Evidence Supporting Normothermic Regional and Machine Perfusion as Standards of Care
Posted inGastroenterology General Surgery news

Advancing Donation After Circulatory Death Liver Transplantation: National Evidence Supporting Normothermic Regional and Machine Perfusion as Standards of Care

A comprehensive national study shows both normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) significantly improve graft survival in DCD liver transplantation, supporting their adoption as complementary standards of care in the U.S.