Long-Term Clinical Outcomes of Zika-Related Microcephaly: Insights from the First Five Years of Life

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The study followed 181 children with Zika-related microcephaly over five years, revealing high rates of severe neurological impairment and systemic complications including dysphagia, ophthalmological abnormalities, and frequent hospitalizations primarily due to respiratory issues and seizures.

Severe microcephaly and neurological abnormalities were common, with over 70% showing abnormal neurological findings and cortical atrophy evident in nearly two-thirds of cases by brain imaging.

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