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Gastroenterology

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  • Page 7
Pairing HDV RNA With Anti-HDV Levels May Sharpen Staging and Treatment Monitoring in HBV/HDV Coinfection
Posted inGastroenterology Infectious Diseases news

Pairing HDV RNA With Anti-HDV Levels May Sharpen Staging and Treatment Monitoring in HBV/HDV Coinfection

Posted by MedXY By MedXY 05/04/2026
In HBsAg-positive, anti-HDV-positive patients, combined measurement of HDV RNA and anti-HDV titers distinguished inactive from active disease and tracked interferon response more effectively than either marker alone.
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AI Radiomics Detects Visually Occult Pancreatic Cancer on CT Nearly 16 Months Before Diagnosis and Outperforms Radiologists
Posted inAI Gastroenterology news

AI Radiomics Detects Visually Occult Pancreatic Cancer on CT Nearly 16 Months Before Diagnosis and Outperforms Radiologists

Posted by MedXY By MedXY 05/04/2026
A multi-institutional AI model identified pre-diagnostic pancreatic cancer on routine CT with meaningful lead time, higher sensitivity than radiologists, longitudinal stability, and externally validated specificity in a low-prevalence setting.
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Cancer Risk in Familial Adenomatous Polyposis Remains Broad Despite Preventive Surgery: Dutch Nationwide Data Highlight Rising Gastric Cancer Burden
Posted inGastroenterology news Oncology

Cancer Risk in Familial Adenomatous Polyposis Remains Broad Despite Preventive Surgery: Dutch Nationwide Data Highlight Rising Gastric Cancer Burden

Posted by MedXY By MedXY 05/03/2026
A nationwide Dutch cohort confirms that patients with FAP remain at markedly elevated risk for multiple gastrointestinal and extraintestinal cancers, with gastric cancer emerging as the most frequently diagnosed malignancy since 2020.
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Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study
Posted inGastroenterology General Surgery news

Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study

Posted by MedXY By MedXY 05/01/2026
This nationwide Swedish study reveals that RYGB reversal is rare (0.3% of procedures) but effective for complications like abdominal pain and hypoglycemia. While 86% reported symptom improvement, significant complication risks require careful patient selection and surgical expertise.
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HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD
Posted inGastroenterology Internal Medicine news

HSP72-PRDX6 Control of PINK1 Ubiquitination Emerges as a New Mitophagy Axis in MASLD

Posted by MedXY By MedXY 05/01/2026
A new Hepatology study identifies an HSP72–PRDX6 pathway that restores PINK1/Parkin mitophagy, reduces hepatic steatosis, and worsens MASLD when disrupted in mice and hepatocytes.
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Uncoupling Metabolic Reprogramming in Hepatocellular Carcinoma: The JOSD1-PGAM1 Ubiquitination-Lactylation Switch
Posted inClinical Updates Gastroenterology news Oncology

Uncoupling Metabolic Reprogramming in Hepatocellular Carcinoma: The JOSD1-PGAM1 Ubiquitination-Lactylation Switch

Posted by MedXY By MedXY 05/01/2026
This article explores how the deubiquitinase JOSD1 drives HCC progression by modulating a novel PTM switch on PGAM1, promoting glycolysis and immune evasion while providing a new target for combined immunotherapy.
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Genetic Risk of Inflammatory Bowel Disease Linked to Disease Severity
Posted inGastroenterology news

Genetic Risk of Inflammatory Bowel Disease Linked to Disease Severity

Posted by MedXY By MedXY 05/01/2026
A Danish nationwide study reveals higher genetic risk scores for IBD predict more severe disease courses, including increased surgery rates, stronger medication needs, and worse inflammatory markers in both Crohn's and ulcerative colitis patients.
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Oral Glucose Absorption Enhanced in Early Metabolic Dysfunction-Associated Steatotic Liver Disease
Posted inDiabetes & Endocrinology Gastroenterology news

Oral Glucose Absorption Enhanced in Early Metabolic Dysfunction-Associated Steatotic Liver Disease

Posted by MedXY By MedXY 04/30/2026
New research reveals accelerated glucose absorption in early MASLD patients, independent of gastric emptying. This metabolic alteration may drive liver disease progression before hepatic insulin resistance develops.
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Early MASLD Is Associated With Enhanced Oral Glucose Absorption Independent of Gastric Emptying
Posted inDiabetes & Endocrinology Gastroenterology news

Early MASLD Is Associated With Enhanced Oral Glucose Absorption Independent of Gastric Emptying

Posted by MedXY By MedXY 04/30/2026
Stable-isotope OGTT data suggest that early MASLD is linked to higher oral glucose absorption, independent of gastric emptying, with preserved hepatic insulin suppression but impaired peripheral glucose clearance.
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CD276 Identified as Key Driver of Chemoresistance in Advanced Pancreatic Cancer
Posted inGastroenterology news Oncology

CD276 Identified as Key Driver of Chemoresistance in Advanced Pancreatic Cancer

Posted by MedXY By MedXY 04/29/2026
Single-cell analysis reveals CD276/B7-H3 as a critical regulator of chemoresistance in pancreatic ductal adenocarcinoma, highlighting its dual role in promoting basal-like tumor states and immune evasion.
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Fecal Microbiota Transplant Fails to Decolonize Multidrug-Resistant Organisms in GI Patients: A Randomized Trial Analysis
Posted inGastroenterology Infectious Diseases news

Fecal Microbiota Transplant Fails to Decolonize Multidrug-Resistant Organisms in GI Patients: A Randomized Trial Analysis

Posted by MedXY By MedXY 04/27/2026
A randomized clinical trial found that FMT did not significantly decolonize MDROs or reduce AMR genes in GI disease patients, though it modulated gut microbiome composition.
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Early Enteral Nutrition Reduces Postoperative Complications in High-Risk Pancreatoduodenectomy Patients
Posted inGastroenterology General Surgery news

Early Enteral Nutrition Reduces Postoperative Complications in High-Risk Pancreatoduodenectomy Patients

Posted by MedXY By MedXY 04/26/2026
The NUTRIWHI trial demonstrates that early enteral nutrition via nasojejunal tube significantly reduces complication burden in nutritionally high-risk patients after pancreatoduodenectomy compared to oral nutrition alone.
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Mucosal Impedance: A Novel Diagnostic Tool for Refining GERD Phenotyping and Surgical Decision-Making
Posted inGastroenterology General Surgery news

Mucosal Impedance: A Novel Diagnostic Tool for Refining GERD Phenotyping and Surgical Decision-Making

Posted by MedXY By MedXY 04/26/2026
Mucosal impedance (MI) offers a groundbreaking approach to assess esophageal mucosal integrity in GERD, complementing traditional diagnostics and enhancing surgical outcomes.
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Combination Therapy with GLP-1 Receptor Agonists and SGLT-2 Inhibitors Reduces Liver and Cardiovascular Risks in MASLD and Type 2 Diabetes
Posted inDiabetes & Endocrinology Gastroenterology news

Combination Therapy with GLP-1 Receptor Agonists and SGLT-2 Inhibitors Reduces Liver and Cardiovascular Risks in MASLD and Type 2 Diabetes

Posted by MedXY By MedXY 04/25/2026
A study reveals that combining GLP-1 receptor agonists with SGLT-2 inhibitors significantly lowers the risk of major adverse liver and cardiovascular outcomes in patients with MASLD and type 2 diabetes compared to monotherapy.
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CD16+ γδ T Cells: A Novel Player in HBV Viral Control Through Antibody-Dependent Cytotoxicity
Posted inGastroenterology Infectious Diseases news

CD16+ γδ T Cells: A Novel Player in HBV Viral Control Through Antibody-Dependent Cytotoxicity

Posted by MedXY By MedXY 04/25/2026
A study reveals CD16+ γδ T cells as key mediators of antibody-dependent cellular cytotoxicity in HBV infection, correlating with reduced viral replication and offering new therapeutic targets.
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Clonal Lymphocyte Expansions and JAK-STAT Mutations Drive Refractory Celiac Disease
Posted inGastroenterology Hematology-Oncology news

Clonal Lymphocyte Expansions and JAK-STAT Mutations Drive Refractory Celiac Disease

Posted by MedXY By MedXY 04/25/2026
This study uncovers clonal lymphocyte expansions and JAK-STAT pathway mutations as key drivers of refractory celiac disease, suggesting a shared pathogenic continuum between RCD1 and RCD2 while cautioning against JAK inhibitor monotherapy due to resistance risks.
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A New Framework to Refine Hepatocellular Cancer Surveillance with Risk Stratification Models
Posted inGastroenterology news Oncology

A New Framework to Refine Hepatocellular Cancer Surveillance with Risk Stratification Models

Posted by MedXY By MedXY 04/23/2026
The Translational Liver Cancer Consortium proposes a structured framework for developing and validating risk models to optimize HCC surveillance, addressing gaps in current clinical guidelines.
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Protein Misfolding in the Gut: A Window into Future Neurodegeneration
Posted inGastroenterology Neurology news

Protein Misfolding in the Gut: A Window into Future Neurodegeneration

Posted by MedXY By MedXY 04/23/2026
GI biopsies reveal misfolded proteins years before neurological symptoms appear, offering a new biomarker for early neurodegenerative disease prediction and intervention.
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Somatostatin in the Gut: No Diabetes-Specific Patterns Found
Posted inDiabetes & Endocrinology Gastroenterology news

Somatostatin in the Gut: No Diabetes-Specific Patterns Found

Posted by MedXY By MedXY 04/22/2026
New study reveals uniform distribution of somatostatin and its receptors throughout the intestinal tract in both healthy individuals and type 2 diabetes patients, challenging previous assumptions about its role in diabetes pathophysiology.
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Unraveling the Gut-Heart Connection: How Leaky Gut Fuels Atrial Fibrillation in Aging
Posted inCardiology Gastroenterology news

Unraveling the Gut-Heart Connection: How Leaky Gut Fuels Atrial Fibrillation in Aging

Posted by MedXY By MedXY 04/22/2026
Researchers identify JNK2 as a key mediator in gut-heart crosstalk, linking intestinal permeability to atrial fibrillation pathogenesis through inflammatory stress signals, offering new therapeutic targets.
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  • Global Axial Length Centile Charts: A New Reference for Myopia Management in Children and Adolescents
  • Systemic Interleukin-6 Inhibition as a Novel Approach to Reduce Diabetic Retinopathy Risk and Progression
  • Patient Characteristics Influencing Treatment Choices in Bilateral Vocal Fold Atrophy: Insights from a Decade of Clinical Data
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