Highlight
• Liver stiffness measurement (LSM) by Fibroscan® robustly predicts transplant-free survival in PSC.
• Stratification into Baveno-VII classes (<10, 10–<15, ≥15 kPa) correlates strongly with outcome.
• Dynamic LSM changes over time independently add prognostic value beyond baseline measures.
• Incremental LSM progression corresponds to a significant increase in risk of death or transplantation.
