Development and Validation of a Noninvasive Score for At-Risk Metabolic Dysfunction-Associated Steatohepatitis in Individuals with Obesity Undergoing Bariatric Surgery
Posted inDiabetes & Endocrinology Gastroenterology news

Development and Validation of a Noninvasive Score for At-Risk Metabolic Dysfunction-Associated Steatohepatitis in Individuals with Obesity Undergoing Bariatric Surgery

Researchers developed and validated the FMO score, a noninvasive, cost-effective tool to identify at-risk metabolic dysfunction-associated steatohepatitis (MASH) in obese patients, showing strong predictive performance across multiple international cohorts.
Vibration-Controlled Transient Elastography vs. Liver Histology: Head-to-Head Prognostic Comparison in Metabolic Dysfunction-Associated Steatotic Liver Disease
Posted inGastroenterology Internal Medicine news

Vibration-Controlled Transient Elastography vs. Liver Histology: Head-to-Head Prognostic Comparison in Metabolic Dysfunction-Associated Steatotic Liver Disease

This study demonstrates that vibration-controlled transient elastography offers prognostic accuracy comparable to liver histology for predicting liver-related events in MASLD, supporting its role as a noninvasive alternative in clinical practice and trials.
Functional Anti-preS1 Antibody Responses and Their Role in Viral Control in Chronic Hepatitis B
Posted inClinical Updates Gastroenterology Infectious Diseases news

Functional Anti-preS1 Antibody Responses and Their Role in Viral Control in Chronic Hepatitis B

This review synthesizes evidence on preS1 antigen and anti-preS1 IgG dynamics in chronic hepatitis B, highlighting their correlations with viral replication, liver inflammation, and functional cure, and elucidates the neutralising potential of anti-preS1 antibodies as markers of endogenous viral control.
Preservation of Islet Function and Glycaemic Control After Total Pancreatectomy with Islet Autotransplantation: Insights From Continuous Glucose Monitoring
Posted inDiabetes & Endocrinology Gastroenterology news

Preservation of Islet Function and Glycaemic Control After Total Pancreatectomy with Islet Autotransplantation: Insights From Continuous Glucose Monitoring

This study demonstrates that nearly half of islet secretory function is preserved following total pancreatectomy with islet autotransplantation (TPIAT), independent of preoperative glycaemic status or prior pancreatic surgery. Continuous glucose monitoring reveals meaningful correlations between islet function and glycaemic control post-TPIAT.