Normothermic machine perfusion (NMP) and normothermic regional perfusion (NRP) improve 2-year graft survival in donation after circulatory death (DCD) liver transplants, closing the gap versus donation after brain death (DBD) grafts.
Both NMP and NRP demonstrate comparable graft survival outcomes when directly compared using propensity score matching.
Static cold storage (SCS) of DCD livers is associated with significantly increased graft loss and ischemic cholangiopathy risk.
Advanced perfusion techniques should be routinely considered to optimize DCD liver transplant outcomes.
