奥希替尼联合萨沃替尼为晚期 EGFR 突变 NSCLC 合并 MET 异常患者带来生存获益
Posted inClinical Updates Oncology Respiratory

Enhanced Survival with Osimertinib and Savolitinib Combination in Advanced EGFR-Mutated NSCLC with MET Dysregulation Post-Osimertinib Progression

The phase 3 SAFFRON trial demonstrated that osimertinib combined with savolitinib significantly improves progression-free and overall survival versus platinum-pemetrexed chemotherapy in advanced EGFR-mutated NSCLC harboring MET overexpression or amplification after osimertinib failure.
提升间质性肺疾病诊断：支气管内光学相干断层成像在多学科评估中的作用
Posted inClinical Updates Pathology & Lab Medicine Respiratory

Enhancing Interstitial Lung Disease Diagnosis: The Role of Endobronchial Optical Coherence Tomography in Multidisciplinary Evaluation

This study highlights the diagnostic value of endobronchial optical coherence tomography (EB-OCT) as a complementary, low-risk imaging modality that improves confidence and diagnostic accuracy in interstitial lung disease multidisciplinary discussions alongside TBLC and genomic classifiers.
揭示成人先天性中枢性低通气综合征的呼吸感受：静息与CO2重复吸入过程中的呼吸困难特征分析
Posted inNeurology news Respiratory

Unveiling Respiratory Sensations in Adults with Congenital Central Hypoventilation Syndrome: Insights from Dyspnea Profiling During Rest and CO2 Rebreathing

This article explores the surprising presence of conscious respiratory unpleasantness and dyspnea in adults with congenital central hypoventilation syndrome (CCHS) despite severely impaired central CO2 chemosensitivity, revealing potential alternative neural pathways for respiratory perception.
亚实性结节及磨玻璃结节患者的自然病程、治疗、生存情况及死亡原因：一项全面的临床综述
Posted inClinical Updates news Respiratory

Natural History, Treatment, Survival, and Causes of Mortality in Patients With Subsolid and Ground-Glass Nodules: A Comprehensive Clinical Review

This review synthesizes current evidence on subsolid nodules (SSNs) and ground-glass opacities (GGOs), focusing on their natural history, treatment strategies including ablation and surgery, survival outcomes, and mortality causes. It highlights the safe observational approach for many SSNs and explores emerging minimally invasive treatments.
急诊腹部手术后，综合呼吸与功能训练可促进撤机并加速恢复：来自随机对照试验的启示
Posted inCritical Care news Respiratory

Integrated Respiratory and Functional Training Enhances Weaning and Recovery After Emergency Abdominal Surgery: Insights from a Randomized Controlled Trial

This RCT demonstrates that combining multidimensional functional training with inspiratory muscle training and chest physiotherapy improves weaning success, muscle strength, functional independence, pain reduction, and ICU stay following emergency abdominal surgery.