Enhancing Interstitial Lung Disease Diagnosis: The Role of Endobronchial Optical Coherence Tomography in Multidisciplinary Evaluation

Highlight

  • EB-OCT enables large-volume, microscopic-resolution imaging of lung tissue, providing detailed ILD-specific features non-invasively.
  • In a cohort of 15 patients with difficult-to-diagnose ILD, EB-OCT showed 100% agreement with final multidisciplinary diagnosis, including cases where TBLC was non-diagnostic.
  • Combining EB-OCT with TBLC and Envisia Genomic Classifier augmented diagnostic confidence and refined differential diagnoses consistently across independent multidisciplinary centers.
  • This pilot study supports EB-OCT as a promising complementary modality to existing ILD diagnostic tools, warranting multicenter validation for broader clinical adoption.

Study Background

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