Medxy AI – Page 11

Uncovering Novel Genetic Contributors to Usher Syndrome: Insights from Comprehensive Mouse Knockout Models

By MedXY 10/26/2026

A large-scale phenotypic screen of 9,139 knockout mouse lines identified 18 candidate genes linked to retinal and hearing abnormalities, offering promising new targets for understanding and diagnosing Usher syndrome.

news Otorhinolaryngology

Enhancing Nasal Septal Perforation Repair: The Role of Contralateral Free Mucosal Grafting for Rapid Re-Epithelialization

By MedXY 10/26/2026

Free mucosal grafting on the contralateral side during nasal septal perforation repair enhances healing, achieving over 90% anatomical closure with rapid re-epithelialization and improved nasal symptoms.

Gastroenterology General Surgery news

Unveiling the Microbiome Landscape of Anastomotic Leaks After Foregut Surgery: Implications for Management and Outcomes

By MedXY 10/26/2026

This study explores how microbiome compositions differ in patients with foregut anastomotic leaks managed endoscopically versus surgically, highlighting nutrition and microbial patterns as key factors influencing healing.

Diabetes & Endocrinology news OB/GYN & Women's Health

Unraveling the Complex Interplay of BMI and Inflammation on Assisted Reproductive Outcomes in PCOS Women

By MedXY 10/26/2026

This study reveals bidirectional mediation between BMI and inflammatory markers affecting embryo quality and availability in PCOS women undergoing ART, highlighting BMI's predominant role.

Neurology news

Disparities in Utilization and Adherence to Antiamyloid Therapies in Alzheimer’s Disease and Mild Cognitive Impairment

By MedXY 10/26/2026

This study reveals that younger, non-Hispanic White patients with fewer comorbidities and lower socioeconomic vulnerability are more likely to receive antiamyloid medications for Alzheimer’s, while higher comorbidity predicts lower initial adherence.

news Oncology Otorhinolaryngology

Optimizing Neck Radiation in Advanced Differentiated Thyroid Carcinoma: Balancing Locoregional Control and Toxicity through Field Reduction

By MedXY 10/26/2026

This study demonstrates that reducing radiation fields in advanced differentiated thyroid carcinoma lowers toxicity without compromising locoregional tumor control, supporting personalized radiotherapy strategies.

Clinical Updates news Orthopedics

Quadriceps Strength Recovery Trajectories Following ACL Reconstruction: Associations with Preoperative Predictors but Not Clinical Outcomes

By MedXY 10/26/2026

Quadriceps strength recovery after ACL reconstruction exhibits three distinct trajectories linked to preoperative strength and meniscectomy status, yet these trajectories do not correlate with postoperative clinical outcomes at one year.

Neurology news Public Health

Enhancing Post-Stroke Physical Activity Through Telehealth and Wearable Technology: A Feasibility Randomised Controlled Trial

By MedXY 10/25/2026

A feasibility RCT demonstrates that a telehealth-delivered behaviour change intervention, augmented with a physical activity monitor, can increase physical activity in post-stroke individuals, supporting future large-scale trials.

Dentistry news

Advancing Dental Education: Repair Versus Replacement of Defective Composite Restorations in Canadian Dental Schools

By MedXY 10/25/2026

A comprehensive assessment of the teaching practices regarding repair and replacement of defective composite restorations in Canadian dental schools highlights the move towards minimally invasive dentistry and calls for harmonization of educational standards.

幼儿17DD黄热病疫苗分剂量接种的免疫原性与安全性：乌干达Ⅳ期随机试验及更广泛证据

Clinical Updates news Public Health

Immunogenicity and Safety of Fractional 17DD Yellow Fever Vaccine Doses in Young Children: Evidence from a Phase 4 Randomised Trial in Uganda and Broader Context

By MedXY 10/25/2026

Fractional doses (one-fifth and one-half) of 17DD yellow fever vaccine demonstrate non-inferior immunogenicity and comparable safety to full doses in children aged 9–23 months, supporting dose-sparing strategies during vaccine shortages.

Emergency Medicine news Pediatrics

Enhancing Prehospital Pediatric Ventilation Quality with Real-Time Feedback Devices: Insights from a Randomized Study

By MedXY 10/25/2026

A randomized crossover study reveals that manual ventilation quality in pediatric respiratory arrest is suboptimal among EMS clinicians, but use of a ventilation feedback device significantly improves adherence to pediatric ventilation guidelines.

nerandomilast有望减缓自身免疫性进行性肺纤维化：FIBRONEER-ILD试验带来新证据

news Respiratory Rheumatology

Nerandomilast Shows Promise in Slowing Progressive Pulmonary Fibrosis in Autoimmune Disease: Insights from the FIBRONEER-ILD Trial

By MedXY 10/25/2026

The FIBRONEER-ILD trial demonstrates nerandomilast’s potential to slow lung function decline and reduce mortality in patients with autoimmune-related progressive pulmonary fibrosis, with a favorable safety profile.

news Respiratory

Long-Term Proton Pump Inhibitor Use Post-Lung Transplantation: Near-Universal but No Clear Benefit on Clinical Outcomes Over Two Decades

By MedXY 10/25/2026

A 20-year observational study reveals near-universal long-term proton pump inhibitor use in lung transplant recipients without demonstrable improvements in graft function or survival, challenging routine PPI prescriptions in this population.

Ivarmacitinib 在掌跖脓疱病中展现快速且令人鼓舞的疗效与免疫调节作用：多中心临床试验启示

Allergy & Immunology Dermatology news

Ivarmacitinib Shows Promising Rapid Efficacy and Immune Modulation in Palmoplantar Pustulosis: Insights from a Multicenter Clinical Trial

By MedXY 10/25/2026

Ivarmacitinib, a selective JAK1 inhibitor, demonstrated rapid efficacy and immune remodeling in palmoplantar pustulosis over 12 weeks, with favorable safety and potential biomarkers for response stratification.

清醒镇静联合TAP block与肿胀麻醉在门诊脂肪抽吸联合腹壁整形术中的应用：一种安全有效的镇痛策略

Anesthesiology news Plastic Surgery

Outpatient Lipoabdominoplasty Using Sedation, TAP Block, and Tumescent Anesthesia: A Safe and Effective Pain Management Strategy

By MedXY 10/25/2026

This study demonstrates that lipoabdominoplasty performed under sedation with TAP block and tumescent anesthesia is safe, effective, and feasible in an outpatient setting, offering excellent pain control, minimal nausea, and high patient satisfaction.

远程重症监护能力与重症 Medicare 患者跨院转运及潜在低价值转运的关联：全国性证据综合

Clinical Updates Critical Care news

Association of Tele-Critical Care Capability With Interhospital Transfers and Potentially Low-Value Transfers Among Critically Ill Medicare Beneficiaries: A Nationwide Evidence Synthesis

By MedXY 10/25/2026

This review synthesizes evidence linking tele-critical care with interhospital transfer patterns and outcomes, highlighting improved transfer selection and reduced low-value transfers among critically ill Medicare patients.

Internal Medicine news Superintelligence

Enhancing Ambulatory Care: Patient Experiences with Ambient AI Scribes

By MedXY 10/25/2026

This qualitative study explores how ambient AI scribes affect ambulatory patient experience, revealing improvements in communication, visit thoroughness, and patient comfort influenced by demographic and relational factors.

老年新诊断AML患者中米哚妥林联合低剂量阿糖胞苷与维奈克拉：INTERVENE II期试验的证据与启示

Clinical Updates Hematology-Oncology news

Combining Midostaurin with Low-Dose Cytarabine and Venetoclax in Older Adults with Newly Diagnosed AML: Evidence and Implications from the INTERVENE Phase 2 Trial

By MedXY 10/25/2026

The INTERVENE trial reveals that adding midostaurin to low-dose cytarabine and venetoclax is tolerable and improves FLT3-ITD clearance and survival in older AML patients with FLT3-ITD, addressing resistance in this high-risk subgroup.

news OB/GYN & Women's Health Respiratory

Fertility, Pregnancy, and Women’s Health in Bronchiectasis: Insights from a Multicenter Study and Global Patient Survey

By MedXY 10/25/2026

Women with bronchiectasis face unique reproductive challenges, particularly those with primary ciliary dyskinesia (PCD). Pregnancy often involves exacerbations, but neonatal outcomes remain generally favorable with proper pulmonary care.

news Ophthalmology

Optimizing Intraocular Lens Power Calculations in Extremely Long Eyes: The Role of Axial Length Adjustment and AL/R Ratio

By MedXY 10/25/2026

This study highlights the superiority of the Holladay 1 formula combined with Wang-Koch axial length adjustment in predicting refractive outcomes in eyes with axial length ≥30 mm, introducing the AL-to-corneal radius ratio as a novel stratification biomarker to improve IOL power calculations.

Uncovering Novel Genetic Contributors to Usher Syndrome: Insights from Comprehensive Mouse Knockout Models

Enhancing Nasal Septal Perforation Repair: The Role of Contralateral Free Mucosal Grafting for Rapid Re-Epithelialization

Unveiling the Microbiome Landscape of Anastomotic Leaks After Foregut Surgery: Implications for Management and Outcomes

Unraveling the Complex Interplay of BMI and Inflammation on Assisted Reproductive Outcomes in PCOS Women

Disparities in Utilization and Adherence to Antiamyloid Therapies in Alzheimer’s Disease and Mild Cognitive Impairment

Optimizing Neck Radiation in Advanced Differentiated Thyroid Carcinoma: Balancing Locoregional Control and Toxicity through Field Reduction

Quadriceps Strength Recovery Trajectories Following ACL Reconstruction: Associations with Preoperative Predictors but Not Clinical Outcomes

Enhancing Post-Stroke Physical Activity Through Telehealth and Wearable Technology: A Feasibility Randomised Controlled Trial

Advancing Dental Education: Repair Versus Replacement of Defective Composite Restorations in Canadian Dental Schools

Immunogenicity and Safety of Fractional 17DD Yellow Fever Vaccine Doses in Young Children: Evidence from a Phase 4 Randomised Trial in Uganda and Broader Context

Enhancing Prehospital Pediatric Ventilation Quality with Real-Time Feedback Devices: Insights from a Randomized Study

Nerandomilast Shows Promise in Slowing Progressive Pulmonary Fibrosis in Autoimmune Disease: Insights from the FIBRONEER-ILD Trial

Long-Term Proton Pump Inhibitor Use Post-Lung Transplantation: Near-Universal but No Clear Benefit on Clinical Outcomes Over Two Decades

Ivarmacitinib Shows Promising Rapid Efficacy and Immune Modulation in Palmoplantar Pustulosis: Insights from a Multicenter Clinical Trial

Outpatient Lipoabdominoplasty Using Sedation, TAP Block, and Tumescent Anesthesia: A Safe and Effective Pain Management Strategy

Association of Tele-Critical Care Capability With Interhospital Transfers and Potentially Low-Value Transfers Among Critically Ill Medicare Beneficiaries: A Nationwide Evidence Synthesis

Enhancing Ambulatory Care: Patient Experiences with Ambient AI Scribes

Combining Midostaurin with Low-Dose Cytarabine and Venetoclax in Older Adults with Newly Diagnosed AML: Evidence and Implications from the INTERVENE Phase 2 Trial

Fertility, Pregnancy, and Women’s Health in Bronchiectasis: Insights from a Multicenter Study and Global Patient Survey

Optimizing Intraocular Lens Power Calculations in Extremely Long Eyes: The Role of Axial Length Adjustment and AL/R Ratio

Exercise as a Cognitive Buffer in Midlife Women: Insights into Domain-Specific Effects and Modality Differences

Empowering Safer Mobility Behaviors to Prevent Falls in Parkinson’s Disease: Insights from Clinicians and Researchers

Eating Difficulty as a Marker for Broader Functional Vulnerability and Cognitive Decline in Older Adults: Insights from Four Large Ageing Cohorts

Izalontamab Brengitecan Shows Promising Efficacy Over Platinum Chemotherapy in EGFR-Mutated NSCLC Post-Third-Generation EGFR TKI Progression