Defining a Quantitative Perfusion Threshold with SPY-PHI QP to Predict Mastectomy Skin Necrosis in Breast Reconstruction: Insights and Clinical Implications

Defining a Quantitative Perfusion Threshold with SPY-PHI QP to Predict Mastectomy Skin Necrosis in Breast Reconstruction: Insights and Clinical Implications

This prospective study identifies a 30% SPY-PHI QP perfusion threshold predictive of mastectomy skin flap necrosis in staged breast reconstruction, highlighting the confounding effect of nitroglycerin ointment and underscoring the need for refined intraoperative tissue assessment.
Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes

Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes

Persistent high-risk HPV infection with normal or low-grade cytology carries a significant risk of high-grade cervical lesions, especially in younger women and those with atypical cytology. Colposcopy shows low sensitivity, urging careful biopsy protocols.
Disparities in Gynecologic Cancer Diagnosis in the U.S. (2001–2019): The Roles of Race, Social Vulnerability, and Specialist Access

Disparities in Gynecologic Cancer Diagnosis in the U.S. (2001–2019): The Roles of Race, Social Vulnerability, and Specialist Access

This analysis of nearly 1.4 million U.S. gynecologic cancer cases reveals that racial/ethnic minorities, socially vulnerable communities, and women lacking geographic access to gynecologic oncologists face higher odds of late-stage cancer diagnosis, with implications for targeted interventions.