Progestin-only contraceptive users reported higher mood-related discontinuation rates within the first 6 months compared to combined hormonal or nonhormonal users.
Among progestin-only users, implants and injections were most commonly associated with mood-related discontinuation.
Individuals with frequent baseline mood symptoms were less likely to discontinue progestin-only methods early, suggesting preexisting mood states may influence continuation behaviors.
Findings underscore the importance of individualized counseling addressing mood-related concerns when selecting contraceptive methods.
