Evaluating CT-Based Models to Predict Residual Disease and Surgical Extent in Interval Debulking Surgery for Ovarian Cancer

Evaluating CT-Based Models to Predict Residual Disease and Surgical Extent in Interval Debulking Surgery for Ovarian Cancer

This study assesses the predictive accuracy of the MSKCC CT-based model for residual disease after neoadjuvant chemotherapy in advanced ovarian cancer, showing limited discrimination that improves with optimized clinical parameters. CT findings guide surgical planning but cannot exclude complex procedures.
Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study

Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study

This prospective multicenter study demonstrates that cfDNA fetal risk screening accurately identifies autosomal recessive conditions in general-risk pregnancies with high specificity and improved positive predictive value compared to traditional carrier screening, supporting its potential as a primary screening tool.
Evaluating the Long-Term Impact of Electrical Stimulation Biofeedback Combined with Pelvic Floor Muscle Training for Postpartum Pelvic Organ Prolapse

Evaluating the Long-Term Impact of Electrical Stimulation Biofeedback Combined with Pelvic Floor Muscle Training for Postpartum Pelvic Organ Prolapse

A randomized controlled trial shows that adding electrical stimulation biofeedback to pelvic floor muscle training offers limited long-term anatomical improvement for postpartum pelvic organ prolapse but improves muscle strength without significant quality-of-life gains.