Histopathologic Insights in Chronic Rhinosinusitis Linked to Intranasal Substance Use: Implications for Clinical Management
Posted innews Otorhinolaryngology Pathology & Lab Medicine/Bệnh học

Histopathologic Insights in Chronic Rhinosinusitis Linked to Intranasal Substance Use: Implications for Clinical Management

This study reveals distinct histopathologic features in chronic rhinosinusitis patients with intranasal substance use, highlighting increased neutrophilic inflammation and epithelial remodeling, underscoring the need for targeted clinical assessment and postoperative care.
Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes
Posted innews OB/GYN & Women’s Health Pathology & Lab Medicine/Bệnh học

Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes

Persistent high-risk HPV infection with normal or low-grade cytology carries a significant risk of high-grade cervical lesions, especially in younger women and those with atypical cytology. Colposcopy shows low sensitivity, urging careful biopsy protocols.
Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study
Posted innews OB/GYN & Women’s Health Pathology & Lab Medicine/Bệnh học

Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study

This prospective multicenter study demonstrates that cfDNA fetal risk screening accurately identifies autosomal recessive conditions in general-risk pregnancies with high specificity and improved positive predictive value compared to traditional carrier screening, supporting its potential as a primary screening tool.
Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio
Posted inNeurology news Pathology & Lab Medicine/Bệnh học

Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio

Plasma phosphorylated tau biomarkers overlap in Alzheimer’s and prion diseases, risking diagnostic confusion. The NfL/p-tau217 ratio emerges as an accurate plasma biomarker to distinguish prion diseases from Alzheimer’s, improving diagnostic precision and guiding appropriate clinical management.