Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes
Posted innews OB/GYN & Women’s Health Pathology & Lab Medicine/Bệnh học

Persistent High-Risk HPV Infection Without Major Cytological Abnormalities: Clinical Insights on Colposcopic and Histological Outcomes

Persistent high-risk HPV infection with normal or low-grade cytology carries a significant risk of high-grade cervical lesions, especially in younger women and those with atypical cytology. Colposcopy shows low sensitivity, urging careful biopsy protocols.
Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study
Posted innews OB/GYN & Women’s Health Pathology & Lab Medicine/Bệnh học

Evaluating Cell-Free DNA Testing for Autosomal Recessive Conditions in General-Risk Pregnancies: A Multicenter Prospective Study

This prospective multicenter study demonstrates that cfDNA fetal risk screening accurately identifies autosomal recessive conditions in general-risk pregnancies with high specificity and improved positive predictive value compared to traditional carrier screening, supporting its potential as a primary screening tool.
Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio
Posted inNeurology news Pathology & Lab Medicine/Bệnh học

Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio

Plasma phosphorylated tau biomarkers overlap in Alzheimer’s and prion diseases, risking diagnostic confusion. The NfL/p-tau217 ratio emerges as an accurate plasma biomarker to distinguish prion diseases from Alzheimer’s, improving diagnostic precision and guiding appropriate clinical management.