Testosterone Inhibition and Reduced Risk of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma in Men: Insights from a Large Swedish Cohort

Testosterone Inhibition and Reduced Risk of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma in Men: Insights from a Large Swedish Cohort

A population-based cohort study in Sweden found that use of 5α-reductase inhibitors, which reduce bioactive testosterone, is associated with a 17% lower risk of laryngeal and hypopharyngeal squamous cell carcinoma in men, supporting the hormonal influence on these cancers' male predominance.
Differentiating Allergic Fungal Rhinosinusitis from Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: Insights from Structured Histopathology in a Saudi Cohort

Differentiating Allergic Fungal Rhinosinusitis from Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: Insights from Structured Histopathology in a Saudi Cohort

This study delineates distinct clinical, radiographic, laboratory, and histopathologic features separating allergic fungal rhinosinusitis from eosinophilic chronic rhinosinusitis with nasal polyps in a Middle Eastern tertiary-care cohort.
Awake Integrated Microsurgical Approach for Head and Neck Free Flap Reconstruction in Frail Patients: A Safe and Resource-Efficient Alternative to General Anesthesia

Awake Integrated Microsurgical Approach for Head and Neck Free Flap Reconstruction in Frail Patients: A Safe and Resource-Efficient Alternative to General Anesthesia

This retrospective study compares awake loco-regional anesthesia with sedation (AIM) against general anesthesia for head and neck free flap reconstruction, demonstrating AIM's safety, reduced operative time, and lower ICU use in frail patients.
Impact of Intraoperative Recurrent Laryngeal Nerve Monitoring on Post-Thyroidectomy Airway Outcomes: Insights from a Large National Cohort

Impact of Intraoperative Recurrent Laryngeal Nerve Monitoring on Post-Thyroidectomy Airway Outcomes: Insights from a Large National Cohort

This study demonstrates that intraoperative recurrent laryngeal nerve monitoring during thyroid surgery is independently associated with reduced postoperative airway complications, especially benefiting high-risk patients with significant comorbidities and advanced disease.