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Core needle biopsy (CNB) shows excellent sensitivity (93.8%) and specificity (98.5%) for detecting malignancy in major salivary gland tumors. CNB can accurately distinguish benign from malignant lesions, enabling cautious selection of patients who require surgery versus those suitable for observation. The study supports CNB’s clinical utility beyond surgically excised cases by including patients managed conservatively with extended follow-up confirming diagnostic reliability.
