Dermatology – Page 2

International Consensus on Low‑Dose Oral Minoxidil in Children: Practical, Pediatric‑Specific Guidance

By MedXY 10/26/2026

An international expert consensus provides the first pediatric‑specific framework for low‑dose oral minoxidil (LDOM) in children aged 4–11 years: indications, dosing strategies, safety checks, monitoring, contraindications, and long‑term use.

Ivarmacitinib 在掌跖脓疱病中展现快速且令人鼓舞的疗效与免疫调节作用：多中心临床试验启示

Allergy & Immunology Dermatology news

Ivarmacitinib Shows Promising Rapid Efficacy and Immune Modulation in Palmoplantar Pustulosis: Insights from a Multicenter Clinical Trial

By MedXY 10/25/2026

Ivarmacitinib, a selective JAK1 inhibitor, demonstrated rapid efficacy and immune remodeling in palmoplantar pustulosis over 12 weeks, with favorable safety and potential biomarkers for response stratification.

Allergy & Immunology Dermatology news

Litifilimab Shows Promising Efficacy and Safety in Treating Cutaneous Lupus Erythematosus: Insights from the AMETHYST Phase 2 Trial

By MedXY 10/24/2026

The AMETHYST Phase 2 trial demonstrated that litifilimab significantly improves skin symptoms in cutaneous lupus erythematosus with a favorable safety profile, marking a potential new targeted treatment for this challenging condition.

Dermatology news Pediatrics

Telehealth Behavioral Intervention for Melanoma Prevention in Children of Survivors: Insights from a Randomized Clinical Trial

By MedXY 10/23/2026

A telehealth intervention improved sun-protective behaviors among children of melanoma survivors but did not sustain reductions in sunburn rates compared to education alone, highlighting the challenge of long-term melanoma prevention in high-risk youth.

Dermatology news Oncology

Efficacy and Tolerability of Long-Term Low-Dose Capecitabine for Refractory Cutaneous Field Cancerization: Insights from a Retrospective Cohort Study

By MedXY 10/22/2026

This study demonstrates that long-term, low-dose capecitabine significantly reduces keratinocyte carcinoma surgeries in patients with refractory cutaneous field cancerization and is generally well tolerated, offering a promising therapeutic option.

Dermatology news Oncology

Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker in High-Risk Cutaneous Squamous Cell Carcinoma

By MedXY 10/21/2026

Preoperative neutrophil-to-lymphocyte ratio (NLR) predicts poor outcomes in high-risk cutaneous squamous cell carcinoma, offering a cost-effective tool to enhance risk stratification.

Dermatology news Oncology

Cancer Risks in Lichen Planus: Implications from a Nationwide Danish Cohort Study

By MedXY 10/19/2026

Lichen planus is linked to increased risks of oral and genital cancers, with risks correlating to lesion sites. Despite low absolute risks, vigilant cancer surveillance in LP patients is warranted.

Belotero Intense 联合利多卡因用于唇部增大：多中心随机研究证实其安全性与有效性

Dermatology news Plastic Surgery

Evaluating Belotero Intense with Lidocaine for Lip Augmentation: A Multicenter Randomized Study Demonstrates Safety and Efficacy

By MedXY 10/19/2026

This multicenter randomized study confirms that Belotero Intense with lidocaine is a safe and effective hyaluronic acid filler for lip augmentation, showing noninferiority to Restylane Silk and sustained improvement up to 48 weeks.

Dermatology news Pathology & Lab Medicine/Bệnh học

Enhancing Diagnostic Sensitivity for Bullous Pemphigoid: The Emerging Role of LABD97 IgG ELISA

By MedXY 10/18/2026

LABD97 IgG ELISA significantly improves the detection sensitivity for bullous pemphigoid by identifying more patients with circulating autoantibodies compared to traditional BP180 (NC16A) and BP230 ELISAs.

Dermatology news Oncology

COMPASS-SCC: A Novel Prognostic and Staging System Enhancing Risk Stratification in Cutaneous Squamous Cell Carcinoma

By MedXY 10/17/2026

The COMPASS-SCC, developed from a large international cohort, offers improved prognostic accuracy for cutaneous squamous cell carcinoma compared to existing AJCC8 and BWH staging systems, aiding clinical decision-making for metastasis and mortality risk.

Allergy & Immunology Dermatology news

Sonelokimab: A Promising Dual IL-17A/F Nanobody for Moderate-to-Severe Hidradenitis Suppurativa

By MedXY 10/16/2026

The phase 2 MIRA trial shows sonelokimab, an IL-17A/F-inhibiting nanobody, significantly improves outcomes in moderate-to-severe hidradenitis suppurativa with good tolerability compared to placebo.

Dermatology news Plastic Surgery

Comparative Efficacy of PRF, PRGF, Collagen Substitute, and Spontaneous Healing in Palatal Wound Closure: Insights from a Randomised Controlled Trial

By MedXY 10/15/2026

This study evaluates wound healing and pain outcomes among PRF, PRGF, collagen-based dressing, and spontaneous healing in standardized palatal defects, revealing minimal added benefit from adjunctive treatments in healthy individuals.

Dermatology news

Acquired Hair Texture Alteration After Regrowth in Alopecia Areata: A Distinct Clinical and Ultrastructural Phenotype

By MedXY 10/15/2026

Alopecia areata regrowth may present atypically with acquired curly hair texture, associated with pili torti ultrastructural changes, signifying a unique phenotype requiring clinical recognition.

Dermatology Hematology-Oncology news

Refining Prognostication in Advanced Mycosis Fungoides and Sézary Syndrome: The Role of the Cutaneous Lymphoma International Prognostic Index (CLIPI)

By MedXY 10/14/2026

The Cutaneous Lymphoma International Prognostic Index (CLIPI) enhances risk stratification and predicts progression and treatment response beyond conventional staging in advanced mycosis fungoides and Sézary syndrome.

Dermatology news Oncology

Impact of Primary Melanoma Stage on Survival Outcomes in Advanced Disease: Insights from the Spanish Melanoma Registry GEM1801

By MedXY 10/13/2026

Systemic relapse after stage I melanoma, though rare, portends higher tumor burden and poorer survival compared with relapse after stage II/III disease, as evidenced by data from 365 metastatic melanoma patients in the Spanish Melanoma Registry GEM1801.

Dermatology Hematology-Oncology news

Decoding CTCL: A Single-Cell Atlas Reveals Oncogenic Pathways and Immune Resistance Mechanisms

By MedXY 10/08/2026

This study presents a comprehensive single-cell RNA-sequencing atlas of CTCL, identifying oncogenic transcriptional programs and immune microenvironment features that offer new therapeutic targets for advanced-stage disease.

Dermatology news OB/GYN & Women's Health

Comparing CO2 Laser Therapy and Topical Clobetasol in Vulvar Lichen Sclerosus: Breakthroughs in Symptom Management

By MedXY 10/06/2026

A randomized controlled trial demonstrates superior symptom relief with fractional CO2 laser treatment over topical clobetasol in women with vulvar lichen sclerosus, suggesting a novel therapeutic approach.

Dermatology news Pediatrics

Sustained Efficacy and Safety of Dupilumab in Children with Moderate to Severe Atopic Dermatitis: Insights from a 3-Year Dutch Cohort Study

By MedXY 10/02/2026

This study highlights dupilumab's long-term effectiveness and safety in managing pediatric atopic dermatitis over 3 years, revealing age-related differences in symptom control and treatment persistence.

Clinical Updates Dermatology news

Efficacy and Safety of Ruxolitinib Cream in Patients With Cutaneous Lichen Planus: A Randomized Clinical Trial Review

By MedXY 10/02/2026

This review synthesizes current evidence on ruxolitinib 1.5% cream efficacy and safety in cutaneous lichen planus, highlighting significant lesion and pruritus reduction in a pivotal phase 2 RCT, supporting its potential as a novel topical treatment.

Dermatology news Oncology

High-Dose Oral Vitamin D for Management of Chemotherapy- and Radiation-Induced Skin Toxicity: A Multicenter Case Series

By MedXY 10/02/2026

A retrospective series evaluating high-dose oral vitamin D demonstrated rapid improvement and symptom relief in patients with chemotherapy- and radiation-induced skin toxicity without adverse effects, supporting its potential role in oncodermatology supportive care.