Cardiology – Page 16

Blood DNA Methylation Maps Atherosclerosis Across Vascular Beds: Strong Signals, but Mostly a Record of Cumulative Risk Exposure

By MedXY 06/15/2026

In 2 prospective cohorts, blood DNA methylation was associated with carotid, coronary, and peripheral atherosclerosis, but most signals overlapped with smoking and cardiometabolic risk factors rather than vessel-specific biology.

Cardiology news

Can a Sirolimus-Eluting Balloon Reduce Stent Use in De Novo Coronary Disease? New Randomized Evidence from SELUTION DeNovo

By MedXY 06/15/2026

A large randomized trial found sirolimus-eluting balloon with provisional stenting noninferior to routine DES at 1 year by intention-to-treat analysis, though repeat revascularization was slightly higher and per-protocol noninferiority was not confirmed.

Cardiology news

Can a Sirolimus-Eluting Balloon Strategy Rival Routine Stenting in De Novo Coronary Lesions? New Randomized Trial Says Maybe

By MedXY 06/15/2026

An SEB plus provisional stenting strategy was noninferior to routine DES at 1 year for target vessel failure, but repeat revascularization was modestly higher and per-protocol noninferiority was not confirmed.

Cardiology Neurology news

Multiple Sclerosis Does Not Appear to Worsen In-Hospital Outcomes After Cardiovascular Surgery, but Routine Home Discharge Is Less Common

By MedXY 06/11/2026

A large US inpatient analysis found similar in-hospital mortality and complication rates after cardiovascular surgery in patients with and without multiple sclerosis, but patients with MS were less often discharged routinely home.

Cardiology Neurology news

Hypertension-Related High-Risk Features May Identify Which Patients With Cryptogenic Stroke Benefit From Apixaban Instead of Aspirin

By MedXY 06/10/2026

An exploratory ARCADIA analysis suggests that patients with cryptogenic stroke and atrial cardiopathy without severe hypertension-related features may derive greater benefit from apixaban than aspirin, whereas those with high-risk hypertensive features may not.

Cardiology Infectious Diseases news

Culture-Negative Infective Endocarditis in the Modern Diagnostic Era: Patient Characteristics and Heterogeneity in a Nationwide Cohort

By MedXY 06/10/2026

A nationwide Danish study found that culture-negative infective endocarditis was less common than previously reported, often presented without fever or sepsis, and showed higher embolic risk. PET-CT was especially useful in prosthetic valve cases.

Cardiology news

Silent Plaque Ruptures in Non-Obstructive Lesions of Non-Infarct-Related Arteries: What Serial Coronary Imaging Reveals

By MedXY 06/10/2026

In patients with acute myocardial infarction, silent plaque rupture was found in 12% of non-obstructive lesions in non-infarct-related arteries. Larger plaques, positive remodeling, and thinner fibrous caps were linked to rupture, and more than half of untreated ruptures healed over 52 weeks.

Cardiology news Public Health

Low-Level Airborne Particulate Matter and Risk of Hypertension Hospitalization in Older U.S. Adults

By MedXY 06/10/2026

A large U.S. study found that even PM2.5 levels below current federal standards were linked to higher hypertension hospitalization risk in older adults, especially among women and some regional and socioeconomic groups.

Cardiology Diabetes & Endocrinology news

Individual GLP-1 Receptor Agonists and SGLT2 Inhibitors Show Largely Comparable Cardiovascular Protection in Type 2 Diabetes

By MedXY 06/10/2026

A multinational real-world study found broadly similar cardiovascular effectiveness across individual GLP-1 receptor agonists and SGLT2 inhibitors in metformin-treated type 2 diabetes, including among patients with established cardiovascular disease.

Cardiology news

Exploring the Impact of Body Mass Index on Heart Failure Outcomes: Insights from Mendelian Randomization

By MedXY 06/10/2026

This study leverages Mendelian randomization to demonstrate that genetically elevated BMI is associated with increased mortality and adverse cardiovascular outcomes in heart failure, irrespective of ejection fraction status, underscoring potential benefits of weight management.

Cardiology Internal Medicine news

Oral NLRP3 Inhibition With Ruvonoflast Produces Rapid, Reversible Suppression of Residual Inflammation in Adults at High Cardiovascular Risk

By MedXY 06/10/2026

In a Phase 1b placebo-controlled trial, ruvonoflast markedly reduced hsCRP, IL-6, and fibrinogen over 28 days in adults with obesity, elevated hsCRP, and cardiometabolic risk, supporting further evaluation of oral NLRP3 inhibition in atherosclerotic prevention.

Cardiology news Public Health

Low-Level Airborne Particulate Matter and Risk of Hypertension Hospitalization in Older U.S. Adults

By MedXY 06/10/2026

Among more than 26 million older U.S. adults, even PM2.5 levels below current standards were linked to higher hypertension hospitalization risk, suggesting no clearly safe low-exposure threshold.

Cardiology news

Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study

By MedXY 06/10/2026

This study uses Mendelian randomization to show that higher genetically predicted BMI is associated with increased all-cause mortality and cardiovascular events in heart failure patients, regardless of ejection fraction status.

Cardiology news

Arrhythmia Burden and Clinical Responses Under Continuous Monitoring in Heart Failure: Observations From the ALLEVIATE-HF Trial

By MedXY 06/10/2026

Continuous monitoring in heart failure patients revealed a high burden of arrhythmias linked to more interventions, hospitalizations, and heart failure events, but not altered by the study’s congestion-management strategy.

Cardiology Internal Medicine news

Arrhythmia Burden and Clinical Responses Under Continuous Monitoring in Heart Failure: Observations From the ALLEVIATE-HF Trial

By MedXY 06/10/2026

Continuous ICM monitoring in heart failure uncovered a high arrhythmia burden, including atrial fibrillation, bradyarrhythmia, and VT/VF, which was linked to more interventions, hospitalizations, and heart failure events.

Cardiology news Pediatrics

A Mobility-Enabled Active Driver for Berlin Heart EXCOR Showed Zero Major Device Malfunctions in High-Risk Pediatric VAD Support

By MedXY 06/10/2026

In a prospective multicenter study, the EXCOR Active Driver demonstrated excellent reliability and high short-term survival in children requiring ventricular assist support, while supporting a registry-enabled pathway for class III pediatric device evaluation.

Cardiology news

Risk-Based Nurse-Managed Personalized Heart Failure Interventions: The ALLEVIATE-HF Trial

By MedXY 06/10/2026

The ALLEVIATE-HF trial found that implantable monitor-based risk alerts with nurse-managed diuretic treatment were safe but did not significantly improve the main heart failure outcome composite.

Cardiology news

Arrhythmia Burden and Clinical Responses Under Continuous Monitoring in Heart Failure: Findings from the ALLEVIATE-HF Trial

By MedXY 06/10/2026

Continuous implantable monitoring in heart failure revealed a high burden of arrhythmias, strongly linked to hospitalizations and treatment changes, but not reduced by protocol-directed congestion management.

Cardiology news Public Health

The Prognostic Value of Serum Interleukin-6 Concentrations for 9 Cardiovascular and Mortality Outcomes

By MedXY 06/10/2026

Higher blood IL-6 levels were strongly linked to nine cardiovascular and mortality outcomes in nearly 60,000 adults, supporting IL-6 as an important inflammatory marker and potential prevention target.

Cardiology Diabetes & Endocrinology news

Lifestyle-Induced Visceral Fat Loss as a Key Target for Durable Cardiometabolic Health: MRI-Based 5- and 10-Year Follow-Up After Two Clinical Trials

By MedXY 06/10/2026

Long-term follow-up after two lifestyle trials found that reductions in visceral fat, more than overall weight loss, were linked to sustained cardiometabolic benefits and a lower risk of type 2 diabetes.