Portal-Venous Hypothermic Oxygenated Perfusion in Liver Transplantation: Evidence Synthesis from the Bridge to HOPE Trial and Global Clinical Landscape
Posted inClinical Updates General Surgery news Transplantation

Portal-Venous Hypothermic Oxygenated Perfusion in Liver Transplantation: Evidence Synthesis from the Bridge to HOPE Trial and Global Clinical Landscape

This review synthesizes findings from the Bridge to HOPE multicenter trial and other recent evidence, demonstrating that portal-venous hypothermic oxygenated perfusion (HOPE) significantly reduces early allograft dysfunction, improves biliary health, and modulates donor immunogenicity in extended-criteria liver transplantation.
Predictors of Concurrent Endometrial Carcinoma in Minority Populations with Atypical Hyperplasia: A Synthesis of Clinical, Molecular, and Social Evidence
Posted inClinical Updates news

Predictors of Concurrent Endometrial Carcinoma in Minority Populations with Atypical Hyperplasia: A Synthesis of Clinical, Molecular, and Social Evidence

This review synthesizes recent evidence on concurrent endometrial carcinoma risk in atypical hyperplasia, highlighting significant disparities in minority populations, the protective role of adenomyosis, and the emergence of GLP-1 receptor agonists as metabolic modifiers in fertility-sparing management.