Characterization of Patient-Reported Sleep and Mood Symptoms in Chronic Mild Traumatic Brain Injury: A Comprehensive Review

Highlights

  • High prevalence of diverse sleep disturbances including insomnia, excessive daytime sleepiness, and obstructive sleep apnea are reported in chronic mTBI patients, often coexisting with mood disorders.
  • Self-reported sleep impairments significantly correlate with neurobehavioral symptom severity, depression, and anxiety, underscoring complex symptom interdependencies.
  • Sleep quality improvement through targeted interventions may reduce depressive and post-traumatic symptoms and enhance neurocognitive outcomes.
  • Comprehensive screening for sleep disorders should be embedded within chronic mTBI care to optimize recovery and functional outcomes.

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