Enhancing Internal Medicine Resident Competency in Diabetes Care: Comparing Experience-Based and Traditional Continuous Glucose Monitoring Curricula

Enhancing Internal Medicine Resident Competency in Diabetes Care: Comparing Experience-Based and Traditional Continuous Glucose Monitoring Curricula

Experience-based continuous glucose monitoring (CGM) curricula significantly improve internal medicine residents' confidence in applied patient care skills compared to traditional approaches, supporting hands-on CGM training integration in residency programs.
Levothyroxine Treatment and Cardiometabolic Biomarkers in Older Adults with Subclinical Hypothyroidism: A Comprehensive Review

Levothyroxine Treatment and Cardiometabolic Biomarkers in Older Adults with Subclinical Hypothyroidism: A Comprehensive Review

Levothyroxine treatment in older adults with subclinical hypothyroidism shows limited impact on cardiometabolic biomarkers overall but may benefit those with higher TSH levels, highlighting nuanced treatment implications and the need for tailored therapeutic strategies.
Once-weekly IcoSema versus Daily Insulin Glargine U100 in Type 2 Diabetes: Evidence from the COMBINE 4 Phase 3b Trial and Related Advances

Once-weekly IcoSema versus Daily Insulin Glargine U100 in Type 2 Diabetes: Evidence from the COMBINE 4 Phase 3b Trial and Related Advances

COMBINE 4 demonstrated that once-weekly IcoSema (icodec+semaglutide) offers superior glycemic control, weight reduction, and reduced hypoglycemia versus daily insulin glargine U100 in insulin-naive type 2 diabetes patients, supported by complementary phase 3 studies on insulin icodec.
Acute Effects of Cannabis Inhalation on Cardiac Ectopy, Physical Activity, Sleep, and Glucose: A Synthesis of Clinical Evidence and Mechanistic Insights

Acute Effects of Cannabis Inhalation on Cardiac Ectopy, Physical Activity, Sleep, and Glucose: A Synthesis of Clinical Evidence and Mechanistic Insights

This review integrates recent randomized trial data with observational studies to clarify cannabis inhalation's acute impact on cardiac ectopy, physical activity, sleep, and glucose, highlighting complex arrhythmia associations and clinical implications.
Liver, Portal, and Systemic Thyroid Hormone Alterations in End-Stage MASH: Distinct Diagnostic and Prognostic Roles for T3/rT3 Ratio and T4

Liver, Portal, and Systemic Thyroid Hormone Alterations in End-Stage MASH: Distinct Diagnostic and Prognostic Roles for T3/rT3 Ratio and T4

End-stage metabolic dysfunction-associated steatohepatitis (MASH) features profound disruptions in thyroid hormone metabolism across liver, portal, and systemic compartments, with the hepatic T3 level and systemic T3/rT3 ratio serving as sensitive diagnostic biomarkers and systemic T4 correlating with disease severity.