Robust evidence from two large cohorts reveals consistent weekly glycemic variations, with better control mid-week and deterioration on weekends.
Daily diurnal glycemic patterns show optimal glucose control during morning and midday hours on weekdays versus poorer control in evenings and nights, especially weekends.
Bolus insulin dosing rises during weekend days, reflecting compensatory adjustments corresponding to altered glycemic patterns.
Integrating long-term CGM data with temporal analyses enhances personalized diabetes management and clinical interpretation.
