Respiratory – Page 6

Early Biologic Initiation in Severe Asthma: Enhancing Remission and Clinical Outcomes from Global Real-World Cohorts

By MedXY 09/16/2026

Earlier initiation of biologic therapies in severe asthma improves clinical remission rates, reduces exacerbations, preserves lung function, and decreases corticosteroid dependence, supporting a shift from reserving to preserving treatment paradigms.

Critical Care news Respiratory

Extracorporeal Membrane Oxygenation without Mechanical Ventilation in ARDS: Insights from an International Cohort Study

By MedXY 09/16/2026

This study evaluates ECMO as a standalone respiratory support in ARDS patients avoiding invasive mechanical ventilation, highlighting outcomes, strategy failures, and mortality implications.

Clinical Updates news Respiratory

From Mild-to-Moderate to Severe Asthma: Risk Factors and Patient Profiles from the NORDSTAR Cohort and Advances in Severe Asthma Management

By MedXY 09/16/2026

This review summarizes the progression risk from mild-to-moderate to severe asthma based on the NORDSTAR cohort and integrates emerging evidence on biologic therapies that improve severe asthma outcomes across diverse patient profiles.

Cardiology news Respiratory

Distinct Lipid Metabolic Profiles Unveil Pathophysiological Differences Between Postcapillary and Combined Pre- and Postcapillary Pulmonary Hypertension

By MedXY 09/14/2026

This study reveals unique fatty acid and oxylipin metabolic signatures that differentiate isolated postcapillary pulmonary hypertension from combined pre- and postcapillary PH, highlighting potential biomarkers and therapeutic targets.

Cardiology Clinical Updates news Pediatrics Respiratory

Rapid Immunoassay for Molecular Subphenotyping in Pediatric Acute Cardiorespiratory Failure: Clinical Implications and Future Directions

By MedXY 09/13/2026

Rapid immunoassay-based classifiers accurately identify hyper- and hypoinflammatory subphenotypes in critically ill children, preserving prognostic and predictive utility and enabling precision therapies in acute pediatric cardiorespiratory failure.

Clinical Updates news Respiratory

Astegolimab for Chronic Obstructive Pulmonary Disease with Frequent Exacerbations: Insights from the Pooled ALIENTO and ARNASA Trials

By MedXY 09/13/2026

Astegolimab, an anti-ST2 monoclonal antibody, significantly reduced moderate/severe exacerbations in COPD patients with frequent exacerbations in pooled ALIENTO and ARNASA analyses, showing promise for targeting the IL-33/ST2 pathway with good safety.

Allergy & Immunology news Respiratory

Tezepelumab Demonstrates Robust Efficacy and Safety Across Diverse Severe Asthma Phenotypes: Insights from the Phase 4 PASSAGE Study

By MedXY 09/12/2026

The PASSAGE phase 4 study reveals tezepelumab significantly reduces exacerbation rates and improves lung function and quality of life in a broad US severe asthma population, including underrepresented groups and varied phenotypes.

news Respiratory

Efficacy of Dupilumab in Reducing COPD Exacerbations, Emergency Department Visits, and Corticosteroid Use: Insights from a Pooled Phase 3 Analysis

By MedXY 09/12/2026

Dupilumab significantly reduces emergency visits, hospital admissions, and systemic corticosteroid use in COPD patients with type 2 inflammation, offering a promising therapeutic option to mitigate exacerbation-associated morbidity.

news Otorhinolaryngology Respiratory

Prevalence of Voice Fatigue and Its Correlation With Xerostomia in E-Cigarette Smokers

By MedXY 09/12/2026

This study explores the high prevalence of voice fatigue among e-cigarette users and its significant correlation with dry mouth (xerostomia).

Clinical Updates news Public Health Respiratory

Respiratory Syncytial Virus Vaccine Effectiveness in Medicare Beneficiaries Residing in Nursing Homes: A Comprehensive Review

By MedXY 09/10/2026

This review synthesizes emerging evidence demonstrating robust effectiveness of RSV vaccination in reducing hospitalization, death, and severe outcomes among elderly nursing home residents during the vaccine's inaugural season.

news Radiology Respiratory

Enhancing COPD Detection through Integrated Quantitative CT Biomarkers in Lung Cancer Screening Programs

By MedXY 09/10/2026

This study demonstrates that combining quantitative CT biomarkers with clinical data significantly improves the detection of previously undiagnosed COPD within lung cancer screening populations, optimizing referrals for confirmatory spirometry and enabling earlier diagnosis.

Cardiology news Respiratory

Early Identification of PVOD/PCH in Pulmonary Arterial Hypertension: Introducing a Novel Clinical Likelihood Score

By MedXY 09/10/2026

A newly developed clinical likelihood score accurately distinguishes pulmonary arterial hypertension patients with venous or capillary involvement (PVOD/PCH), enabling earlier diagnosis, tailored therapy, and timely transplant referral.

news Respiratory

Expiratory Pressure Alleviation in CPAP Therapy: Impact on Upper Airway Patency and Obstructive Sleep Apnea Control

By MedXY 09/09/2026

Expiratory pressure alleviation during CPAP treatment reduces upper airway patency, increases residual apnea severity, and necessitates higher therapeutic pressure in severe OSA patients, without affecting treatment adherence.

news Respiratory

Optimizing Patient Expectations and Outcomes: Understanding Days Alive and Out of Hospital After Lung Transplantation

By MedXY 09/09/2026

This study evaluates days alive and out of hospital (DAOH) around lung transplantation, identifying predictors of reduced DAOH in the first post-transplant year and providing insights for tailored patient counseling and care strategies.

news Respiratory

Defining and Achieving Disease Stability in COPD: Insights from Phase 3 Trials

By MedXY 09/09/2026

This article explores disease stability as a key treatment target in COPD, analyzing major phase 3 trials that show stability predicts reduced exacerbations and mortality, supporting its use to guide therapy.

news Respiratory

Reevaluating the Frequent Exacerbator Phenotype in Bronchiectasis: Insights from the EMBARC Registry

By MedXY 09/09/2026

Analysis of over 19,000 bronchiectasis patients across 30 countries reveals a graded risk increase for future exacerbations with each prior event, challenging the fixed threshold concept of frequent exacerbators and confirming consistency across etiologies and regions.

Cardiology news Respiratory

Integrating Left Ventricular and Right Atrial Strain for Enhanced Prognostic Prediction in Pulmonary Arterial Hypertension

By MedXY 09/06/2026

Combining left ventricular global longitudinal strain and right atrial reservoir strain greatly improves risk prediction and stratification in pulmonary arterial hypertension, outperforming conventional imaging and clinical models.

Cardiology news Respiratory

Unveiling PUS7’s Role in Pulmonary Hypertension: A Novel Epigenetic Driver of Vascular Remodeling

By MedXY 09/04/2026

This article explores how PUS7-induced pseudouridylation of TGFBI mRNA promotes pulmonary hypertension via epigenetic regulation, revealing promising new therapeutic targets.

Critical Care news Respiratory

Navigating Rehabilitation During ECMO Support: Insights from a Retrospective Cohort Study

By MedXY 09/04/2026

This study explores rehabilitation initiation, progression, and physical activity levels in adult ECMO patients, highlighting early active rehabilitation feasibility and varied activity trajectories based on clinical goals.

Dermatology news Respiratory

Serum Amyloid A as a Prognostic Biomarker in Dermatomyositis-Associated Rapidly Progressive Interstitial Lung Disease

By MedXY 09/03/2026

Elevated serum amyloid A correlates with rapidly progressive interstitial lung disease and mortality in dermatomyositis, with combined assessment alongside anti-MDA5 antibody improving risk stratification.