Specialties – Page 19

Delayed Glaucoma Follow-Up Was Usually Not Linked to Visual Field Progression, but Longer Gaps May Matter in More Advanced Disease

By MedXY 05/18/2026

In a large retrospective glaucoma cohort, delayed follow-up was common yet was not generally associated with visual field worsening, although longer delays appeared more consequential in eyes with worse baseline visual field loss.

Clinical Updates news Ophthalmology Public Health

Optimizing Geographic Atrophy Clinical Trial Design: The Role of Run-In Phases, Single-Arm Architectures, and Functional Endpoints

By MedXY 05/18/2026

This review synthesizes evidence on improving geographic atrophy trial efficiency through innovative run-in phases, single-arm designs, and superior functional biomarkers like microperimetry to reduce required sample sizes.

news Ophthalmology

GLP-1 Weight-Loss and Diabetes Drugs: What Eye Specialists Say About NAION Risk

By MedXY 05/18/2026

A new consensus statement advises cautious, shared decision-making about GLP-1 receptor agonists and NAION risk, noting that current evidence is observational, conflicting, and suggests any absolute risk increase is small.

news Otorhinolaryngology Pediatrics

Identifying High-Risk Children Safe for Same-Day Discharge After Tonsillectomy

By MedXY 05/18/2026

Children with obesity and severe OSA usually stay overnight after tonsillectomy, but this study found most had no major complications. Oxygen nadir and AHI may help identify very low-risk patients who could be considered for same-day discharge.

General Surgery news Oncology

Survival Outcomes After Neoadjuvant Chemotherapy in Node-Positive Hormone Receptor-Positive Breast Cancer”,

By MedXY 05/18/2026

A national database study found that neoadjuvant chemotherapy was linked to worse overall survival than upfront surgery in node-positive hormone receptor-positive, HER2-negative breast cancer, except in patients who achieved nodal complete response.

Gastroenterology news Oncology

Should Some Colon Cancers Be Treated Before Surgery? What a New Trial Means for Patients

By MedXY 05/18/2026

A major randomized trial found that chemotherapy before surgery did not improve 3-year disease-free survival in locally advanced colon cancer, but it still revealed important clues for more personalized treatment.

General Surgery news Oncology

Clipped Axillary Node Pathology May Support Axillary Surgery De-escalation After Neoadjuvant Therapy in Occult Breast Cancer

By MedXY 05/18/2026

In occult breast cancer, clipped-node pathology after neoadjuvant therapy tracked residual axillary disease with high specificity, supporting limited axillary surgery in selected patients, especially those with cN1–cN2 disease.

news OB/GYN & Women’s Health Public Health

Severe Surgical Complications During Cesarean Delivery Are Linked to Higher Postpartum Readmission Risk

By MedXY 05/18/2026

Severe surgical complications during cesarean delivery were linked to about twice the risk of postpartum readmission within 42 days, especially for wound infection, supporting closer follow-up after complicated births.

Gastroenterology news

PBC-AIH Variant: New International Consensus Clarifies Diagnosis and Treatment

By MedXY 05/18/2026

An international Delphi panel has standardized how to define, diagnose, and treat the PBC-AIH variant, emphasizing liver biopsy, periodic reassessment, and tailored immunosuppression for worse-risk patients.

Gastroenterology news Oncology

KRAS-Driven CLDN18.2 O-GlcNAcylation Promotes Pancreatic Cancer Progression and Therapy Resistance

By MedXY 05/16/2026

KRAS mutation and high glucose promote O-GlcNAcylation of CLDN18.2 in pancreatic cancer, pushing the protein off the cell membrane, boosting metastasis, and weakening CLDN18.2-targeted therapy. Low-dose MRTX1133 may restore sensitivity.

Cardiology Neurology news

Prior Myocardial Infarction and Cognitive Decline: Insights from the REGARDS Cohort

By MedXY 05/16/2026

In the REGARDS cohort, prior myocardial infarction, including silent MI, was linked to faster long-term cognitive decline, suggesting heart attack history may help identify people at risk for future cognitive impairment.

Neurology news

Safety and Outcomes of Dabigatran Reversal With Idarucizumab Before IV Thrombolysis in Acute Ischemic Stroke

By MedXY 05/16/2026

Real-world registry data suggest that reversing dabigatran with idarucizumab before IV thrombolysis in acute ischemic stroke is safe and yields outcomes similar to patients not on oral anticoagulants.

Cardiology Neurology news

Effects of Exercise and Intensive Vascular Risk Reduction on Cognitive Function in Older Adults: A Randomized Clinical Trial

By MedXY 05/16/2026

A 24-month randomized trial found that exercise, intensive blood pressure and cholesterol control, or both together did not significantly improve cognitive function in older adults at increased risk for dementia.

news Oncology Pathology & Lab Medicine/Bệnh học

TSH Stimulation Methods Show Comparable Outcomes in Radioiodine-Avid Metastatic Differentiated Thyroid Cancer

By MedXY 05/16/2026

In radioiodine-avid metastatic differentiated thyroid cancer, rhTSH and mixed rhTSH/thyroid hormone withdrawal preparation produced comparable adjusted outcomes. Prognosis was driven mainly by metastatic burden and age, supporting individualized treatment selection.

Allergy & Immunology Diabetes & Endocrinology news

Immune-Cell Transcriptomics and Mendelian Randomisation Identify New Causal Genes for Type 2 Diabetes Complications

By MedXY 05/16/2026

This study used immune-cell gene expression and genetic analyses to identify causal genes and immune pathways linked to type 2 diabetes and its complications, highlighting diabetic neuropathy as a distinct cluster and prioritising ten promising drug targets.

Cardiology Diabetes & Endocrinology news

Retatrutide Produces Broad Favorable Shifts in Fatty Acid Oxidation and Insulin Resistance Biomarkers in Obesity With or Without Type 2 Diabetes

By MedXY 05/16/2026

Post-hoc metabolomic and lipidomic analyses from two phase 2 trials suggest retatrutide favorably remodels metabolic pathways linked to fatty acid oxidation, insulin resistance, and triglyceride composition in obesity, with and without type 2 diabetes.

Diabetes & Endocrinology news Public Health

Improving the Algorithm: Adding a Socioeconomic Measure to Predict Type 2 Diabetes in Youth With Prediabetes

By MedXY 05/16/2026

Adding the Area Deprivation Index to HbA1c improved prediction of type 2 diabetes within 1 year in youth with prediabetes, highlighting the importance of socioeconomic factors in diabetes risk.

news Oncology Pathology & Lab Medicine/Bệnh học

Safety of Biopsy in Pheochromocytoma and Paraganglioma: What a Global Study Found

By MedXY 05/15/2026

This international study found that biopsy of pheochromocytoma and paraganglioma had low mortality and low serious complication rates, suggesting biopsy may be reasonable in carefully selected patients with expert management.

Cardiology news

Heart Failure Medication Adherence Depends Less on Motivation Than on Whether Treatment Fits Daily Life

By MedXY 05/15/2026

A qualitative study in heart failure shows that medication adherence is shaped by regimen complexity, diuretic burden, psychosocial stressors, cost, and care coordination rather than motivation alone.

Cardiology Clinical Updates news

Beyond Neuronal Injury: Serum Neurofilament Light Chain as a Prognostic Biomarker for Cardiovascular Outcomes in Atrial Fibrillation

By MedXY 05/15/2026

This review analyzes the landmark SWISS-AF study, demonstrating that serum neurofilament light chain (sNfL), traditionally a marker of neuronal damage, is a potent independent predictor of major vascular events, heart failure, and mortality in patients with atrial fibrillation.