Specialties – Page 13

FT3/FT4 Ratio Emerges as a Practical Predictor of Relapse After Antithyroid Drug Withdrawal in Children

By MedXY 04/01/2026

In pediatric autoimmune hyperthyroidism, a higher FT3/FT4 ratio predicted relapse after antithyroid drug withdrawal, especially when orbitopathy was present.

Cardiology Clinical Updates Diabetes & Endocrinology news

Precision Phenotyping in Cardiometabolic Medicine: Genetic Susceptibility of Diabetes Subtypes and Coronary Artery Disease Risk

By MedXY 04/01/2026

This review synthesizes evidence on the genetic architecture of adult-onset diabetes subtypes, highlighting that Moderate Obesity-related Diabetes (MOD) is uniquely and causally linked to coronary artery disease risk through polygenic and Mendelian randomization analyses.

Cardiology Diabetes & Endocrinology news

STEMI and NSTEMI Are Not the Same in Type 1 Diabetes: Finnish Cohort Reveals Distinct Risk Patterns

By MedXY 04/01/2026

In Finnish adults with type 1 diabetes, STEMI and NSTEMI showed distinct incidence trends and risk profiles. NSTEMI was more common overall and linked to dyslipidemia and advanced microvascular disease, whereas impaired eGFR tracked more with STEMI.

Cardiology Clinical Updates Diabetes & Endocrinology news

Long-Term Durability and Clinical Stability of Acoramidis in Transthyretin Amyloid Cardiomyopathy: A 54-Month Synthesis

By MedXY 04/01/2026

This review synthesizes the 54-month results of the ATTRibute-CM open-label extension, demonstrating that early and continuous acoramidis treatment provides sustained reductions in mortality and cardiovascular hospitalizations while maintaining functional capacity and biomarker stability in ATTR-CM patients.

Cardiology Internal Medicine news

Cardiologist Evaluation After Postoperative Myocardial Injury Was Linked to Better 1-Year Outcomes

By MedXY 04/01/2026

Post-operative cardiologist evaluation after peri-operative myocardial injury was associated with fewer major cardiac events and lower 1-year mortality in high-risk non-cardiac surgery patients.

Cardiology Clinical Updates news

Optimizing Post-Operative Outcomes: The Critical Impact of Specialist Cardiology Evaluation in Peri-operative Myocardial Infarction and Injury

By MedXY 04/01/2026

This review analyzes evidence demonstrating that cardiologist evaluation for peri-operative myocardial infarction/injury (PMI) significantly reduces 1-year major adverse cardiac events and all-cause mortality through optimized diagnostic and therapeutic interventions.

Cardiology news

IVUS Guidance Slashes 1-Year Target Vessel Failure in Complex Bifurcation PCI: Insights from DKCRUSH VIII

By MedXY 03/31/2026

The DKCRUSH VIII trial demonstrates that IVUS-guided PCI for complex coronary bifurcation lesions significantly reduces 1-year target vessel failure compared to angiography guidance, primarily by ensuring adherence to specific optimization criteria during the double kissing crush technique.

Cardiology Clinical Updates Diabetes & Endocrinology news

Mid-Regional Pro-Adrenomedullin (MR-proADM): A Superior Prognostic Sentinel in Transthyretin Cardiac Amyloidosis

By MedXY 03/31/2026

This review synthesizes recent evidence identifying MR-proADM as a premier prognostic biomarker in ATTR-CM, demonstrating its ability to outperform traditional natriuretic peptides and enhance existing clinical staging systems.

Clinical Updates news Oncology

Optimizing the Synergy: Sequential vs. Concurrent Radiotherapy and Immunotherapy in Advanced Non-Small Cell Lung Cancer

By MedXY 03/31/2026

This review evaluates the optimal sequencing of radiotherapy and immunotherapy in advanced NSCLC, highlighting real-world evidence from the OCEANUS study favoring sequential over concurrent administration.

Cardiology Gastroenterology news

Beyond the Backpressure: Targeting the Integrin αV-YAP-CTGF Axis to Halt Fibrosis in Congestive Hepatopathy

By MedXY 03/31/2026

This study identifies the integrin αV-YAP-CTGF axis in liver sinusoidal endothelial cells as a primary driver of fibrosis and carcinogenesis in congestive hepatopathy. By targeting this mechanosensitive pathway, researchers demonstrated a significant reduction in portal hypertension and liver damage in both murine models and human clinical samples.

Cardiology Clinical Updates news

Advancing Venous Thromboembolism Prediction: Insights from Large-Scale Plasma Proteomics and Mendelian Randomization

By MedXY 03/31/2026

This review synthesizes findings from a landmark proteomic study identifying 23 plasma proteins associated with VTE risk, highlighting novel pathways in immunity and vascular senescence while exploring causal links through Mendelian Randomization.

Internal Medicine news Respiratory

Nerandomilast in Idiopathic Pulmonary Fibrosis: Long-Term Insights from the FIBRONEER-IPF Trial

By MedXY 03/31/2026

An in-depth analysis of the FIBRONEER-IPF trial's extended follow-up data, evaluating the efficacy and safety of the PDE4B inhibitor nerandomilast in reducing clinical events and mortality in patients with idiopathic pulmonary fibrosis.

Cardiology Hematology-Oncology news

Beyond the Clot: Novel Proteomic Markers Reveal New Pathophysiological Pathways for Venous Thromboembolism

By MedXY 03/31/2026

A large-scale proteomic meta-analysis across five cohorts identified 15 novel plasma protein markers for venous thromboembolism, highlighting the roles of the extracellular matrix, immunity, and vascular senescence in disease risk and offering potential new targets for clinical prevention.

Neurology news Ophthalmology

Why the New MS Diagnostic Criteria Require Caution: High Frequency of MOGAD and NMOSD in Optic Neuritis Patients

By MedXY 03/30/2026

A retrospective study reveals that 24% of patients meeting the latest MS criteria following optic neuritis actually have MOGAD or NMOSD, emphasizing the need for antibody testing to prevent misdiagnosis.

Diabetes & Endocrinology news OB/GYN & Women's Health OB/GYN & Women’s Health

Inpatient Postpartum Glucose Testing Triples Completion Rates After Gestational Diabetes

By MedXY 03/30/2026

A randomized controlled trial demonstrates that performing oral glucose tolerance tests before hospital discharge significantly improves screening rates and patient satisfaction compared to standard outpatient care for women with gestational diabetes.

Infectious Diseases Neurology news

Hidden Triggers: Recent Infections Linked to a 2.6-Fold Increase in Cryptogenic Stroke Risk in Young Adults

By MedXY 03/30/2026

The SECRETO study reveals that infections within the preceding week significantly increase the risk of cryptogenic ischemic stroke in patients aged 18–49, with elevated von Willebrand Factor and Factor VIII levels serving as critical biomarkers of this thromboinflammatory response.

Neurology news

PrimeC Combination Therapy Shows Potential to Slow Functional Decline in Amyotrophic Lateral Sclerosis: Insights from the PARADIGM Trial

By MedXY 03/30/2026

The Phase 2b PARADIGM trial demonstrates that PrimeC—a novel combination of celecoxib and ciprofloxacin—is safe and significantly slows functional decline in ALS patients over 18 months, offering new hope for multi-target neuroprotective strategies.

Cardiology news

Synergistic Risk Assessment: Coronary Artery Calcium Scoring Remains Vital in Patients with Elevated Lipoprotein(a)

By MedXY 03/30/2026

A large-scale multicohort study demonstrates that while elevated Lipoprotein(a) increases cardiovascular risk, Coronary Artery Calcium (CAC) scoring remains a powerful independent predictor of events, even in patients with high Lp(a) levels, providing essential clarity for clinical risk stratification.

Clinical Updates news Oncology Pathology & Lab Medicine

Closing the Genomic Gap: Strategies to Enhance Biobanking Participation Among Black Women with Endometrial Cancer

By MedXY 03/30/2026

This review analyzes community-validated strategies to improve biobanking engagement among Black women with endometrial cancer, highlighting return-of-value, transparency, and trust-building as essential components for reducing health disparities in translational research.

news Ophthalmology

Microvascular Dropout and Parapapillary Atrophy Progression Predict Structural Optic Disc Damage in Glaucoma Suspects

By MedXY 03/30/2026

A 19-year retrospective study reveals that microvascular dropout and β-zone parapapillary atrophy progression are powerful independent predictors of structural optic disc damage in glaucoma suspects, even when visual fields remain stable.