Highlight
– The Histolog Scanner enables rapid intraoperative margin assessment during transoral laser microsurgery (TLM) for glottic squamous cell carcinoma.
– Demonstrated high specificity (93.8%) and negative predictive value (97.4%) to confidently rule out involved margins.
– Provides real-time feedback within approximately 13 minutes per specimen, supporting surgical decision-making.
– Serves as a complementary tool to conventional histopathology rather than replacing it.

