Neurology – Page 4

Assessing Early Catheter Ablation in Atrial Fibrillation Patients With Prior Stroke: Insights From a Target Trial Emulation

By MedXY 10/07/2026

Early catheter ablation in atrial fibrillation patients with prior ischemic stroke reduces major adverse cardiovascular events and improves neurological and cognitive outcomes compared to medical therapy, according to a multi-center retrospective target trial emulation.

Clinical Updates Neurology news Pathology & Lab Medicine

Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers: Implications for Diagnosis and Management

By MedXY 10/07/2026

This review synthesizes evidence on clinical and biological factors linked to discordance between plasma p-tau217 and standard AD biomarkers, highlighting implications for diagnosis, patient stratification, and future biomarker development.

Neurology news Public Health

Traumatic Spinal Cord Injury Mortality Trends in the U.S. (1999-2024): Insights into Demographic Disparities and Pandemic Impact

By MedXY 10/07/2026

This study analyzes U.S. traumatic spinal cord injury mortality trends from 1999 to 2024, revealing stable overall rates but notable demographic disparities and pandemic-related mortality increases, highlighting the need for targeted prevention and equitable care.

Emergency Medicine Neurology news

Operational, Ethical, and Technological Priorities for Prehospital Stroke Trials in Conventional EMS: An Expert Consensus Explained

By MedXY 10/05/2026

A clear, clinician-focused summary of the 2026 expert consensus on designing, conducting, and analyzing prehospital stroke trials in routine EMS systems—covering patient identification, consent, trial design, endpoints, and technology priorities.

Clinical Updates Neurology news

Beyond the Threshold: Continuous Creatinine Change and Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke

By MedXY 10/05/2026

Early continuous creatinine changes within 48 hours after EVT correlate with graded risks of poor 90-day functional outcome and in-hospital mortality, revealing prognostic nuances beyond traditional dichotomous CA-AKI definitions.

Cardiology Neurology news

Evaluating Left Atrial Appendage Closure Versus Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation: An Updated Meta-Analysis

By MedXY 10/05/2026

This meta-analysis consolidates data from six RCTs comparing left atrial appendage closure (LAAC) to oral anticoagulation for stroke prevention in atrial fibrillation, highlighting reduced bleeding with LAAC but increased ischemic stroke risk.

Critical Care Neurology news

Evolving Patterns in Withdrawal of Life-Sustaining Treatment Among Traumatic Brain Injury Patients: Insights From a Decade of ACS Trauma Data

By MedXY 10/05/2026

A decade-long analysis reveals a modest decline and delayed timing in withdrawal of life-sustaining treatment among patients with traumatic brain injury, highlighting evolving prognostic attitudes and clinical decision-making.

Neurology news

Skin Denervation as a Biomarker Linked to Cognitive Decline and Brain Atrophy in Parkinson Disease

By MedXY 10/05/2026

Peripheral skin nerve fiber loss correlates with cognitive impairment and brain atrophy in Parkinson disease, suggesting a peripheral-central neurodegenerative axis with potential diagnostic value.

Hematology-Oncology Neurology news

Midterm Cognitive Outcomes After CAR T-Cell Therapy in CNS Lymphoma Patients: Encouraging Evidence Beyond Acute Neurotoxicity

By MedXY 10/05/2026

This study assesses medium-term cognitive changes in CNS lymphoma patients treated with CAR T-cell therapy, revealing cognitive stability or improvement up to 12 months post-treatment, despite initial neurotoxicity risks.

Neurology news

Evaluating SAR443820, a RIPK1 Inhibitor, in Amyotrophic Lateral Sclerosis: Insights from the Phase 2 HIMALAYA Trial

By MedXY 10/05/2026

This phase 2 trial assessed SAR443820, a RIPK1 inhibitor, in ALS patients; it showed no clinical efficacy and increased hepatic side effects, indicating limited therapeutic potential in ALS.

Neurology news Otorhinolaryngology

Racial and Ethnic Disparities in Facial Paralysis: Diagnosis, Comorbidities, and Treatment Inequities

By MedXY 10/05/2026

This article explores racial and ethnic disparities in the diagnosis, associated comorbidities, and treatment, particularly chemodenervation, among patients with facial paralysis, highlighting significant differences and healthcare gaps.

Neurology news

Unraveling Iatrogenic Cerebral Amyloid Angiopathy: Long-Term Disease Progression and Clinical Implications

By MedXY 10/04/2026

Iatrogenic cerebral amyloid angiopathy (iCAA) exhibits high symptomatic intracerebral hemorrhage rates decades after exposure. This analysis of 82 European cases highlights recurrence risks and cognitive outcomes, informing prognosis and patient management.

Neurology news Otorhinolaryngology

Evaluating Hearing Aid Intervention in Older Adults with Mild Cognitive Impairment: Insights from the CHOICE Randomized Clinical Trial

By MedXY 10/04/2026

The CHOICE trial investigated whether hearing aid intervention reduces dementia progression in older adults with mild cognitive impairment and hearing loss, finding no significant reduction in dementia incidence but increased cognitive improvement rates.

Cardiology Neurology news

Hospital Stroke Center Designation Influences Reported Stroke Rates After TAVR: Implications for Quality Assessment

By MedXY 10/04/2026

National data show that Comprehensive Stroke Center status and trial participation independently predict reported stroke rates after TAVR, highlighting potential ascertainment bias affecting hospital performance metrics.

Neurology news

Microvascular Dysfunction After Reperfusion Predicts Stroke Infarct Expansion and Poor Outcomes

By MedXY 10/04/2026

In acute ischemic stroke patients with excellent reperfusion, elevated peri-infarct microvascular heterogeneity measured by MRI predicts infarct growth and poor functional recovery, reflecting the no-reflow phenomenon despite restored macrovascular flow.

Neurology news Plastic Surgery

Earlier Intervention with Migraine Trigger-Site Surgery Linked to Improved Postoperative Headache Outcomes: Insights from a Taiwanese Cohort Study

By MedXY 10/02/2026

A retrospective cohort study reveals that shorter duration from migraine onset to trigger-site surgery predicts better postoperative headache frequency reduction, underscoring the benefit of early surgical intervention in medically refractory migraine patients.

Critical Care Neurology news

Hospital Variation in Early Tracheostomy and Life-Sustaining Treatment Withdrawal in Severe TBI: Insights from a Nationwide Study

By MedXY 10/01/2026

This nationwide study reveals that hospitals with higher tendencies for early tracheostomy in severe TBI patients also show increased rates of withdrawal of life-sustaining treatment, highlighting significant practice variability and its potential impact on patient outcomes.

General Surgery Neurology news

Optimizing Ventriculoperitoneal Shunt Management During Emergency Abdominal Surgery: Evidence from a 25-Year Retrospective Cohort

By MedXY 10/01/2026

This study evaluates shunt preservation strategies in adults with ventriculoperitoneal shunts undergoing emergency abdominal surgery, finding low infection rates and favorable outcomes with shunt retention.

Critical Care Neurology news

Quantitative Pupillometry in Post-Cardiac Arrest Neuroprognostication: Insights from a Bicentric Study

By MedXY 09/30/2026

This bicentric study evaluates quantitative pupillary light reflex (qPLR) alongside EEG, SSEPs, and NSE for neuroprognostication in comatose post-cardiac arrest patients, revealing strong correlations but limitations in sensitivity and predictive value.

Neurology news

Bridging Perspectives: Comparing Patient-Reported and Physician-Assessed Modified Rankin Scale Scores in Chronic Neurologic Disorders in Zambia

By MedXY 09/30/2026

This study evaluates concordance between physician-assessed and patient-reported modified Rankin Scale scores in adults with chronic neurologic disorders in Zambia, revealing substantial agreement but highlighting cultural and symptomatic factors influencing scoring discrepancies.