Neurology – Page 5

Neurotransmitter-Guided Connectome Disruption as a Key to Poststroke Language Impairment

By MedXY 08/15/2026

Damage to serotonergic and dopaminergic neurotransmitter-linked networks predicts variability in acute and chronic poststroke language impairment, offering new insights beyond traditional lesion metrics.

Neurology news Radiology

DWI-Positive Lesions in Acute Intracerebral Hemorrhage: Insights into Cerebral Small Vessel Disease and Prognosis

By MedXY 08/15/2026

DWI-positive lesions in acute intracerebral hemorrhage patients correlate with cerebral small vessel disease markers and predict poorer 6-month outcomes, with lesion distribution varying by small vessel disease subtype.

Neurology news Pathology & Lab Medicine/Bệnh học

Plasma Biomarkers for Neocortical Tau Burden

By MedXY 08/15/2026

A multiprotein plasma panel improves detection of advanced neocortical tau pathology in Alzheimer’s disease risk individuals beyond p-tau217 alone, enhancing patient stratification and clinical trial selection.

Neurology news

Unraveling Lesion Progression in Adult Cerebral Adrenoleukodystrophy to Inform Personalized Management

By MedXY 08/14/2026

This multicenter study characterizes lesion growth variability in adult cerebral adrenoleukodystrophy, highlighting key MRI and biomarker predictors to guide personalized treatment and improve clinical trial designs.

Allergy & Immunology Neurology news

Inebilizumab Significantly Reduces Exacerbations and Need for Rescue Therapy in Generalized Myasthenia Gravis: Insights from the Phase 3 MINT Trial

By MedXY 08/14/2026

The MINT trial demonstrates that inebilizumab markedly lowers exacerbation rates and rescue therapy use in AChR+ and MuSK+ generalized myasthenia gravis patients undergoing corticosteroid tapering.

Internal Medicine Neurology news

Balancing Risks: Antiplatelet Therapy After Intracerebral Haemorrhage in the STATICH Trial

By MedXY 08/14/2026

The STATICH trial assessed safety and efficacy of antiplatelet therapy after intracerebral hemorrhage, revealing increased hemorrhagic risk but fewer ischemic events among treated patients, highlighting ongoing clinical dilemmas.

Neurology news Oncology

Reevaluating Age as a Prognostic Marker in Molecularly Defined Lower-Grade Gliomas

By MedXY 08/13/2026

This article examines how age, traditionally considered a high-risk factor in lower-grade gliomas, influences prognosis and treatment decisions in the molecular era, highlighting the importance of IDH mutation status.

Cardiology Clinical Updates Neurology news

Oral Anticoagulants, Cognition, and Clinical Outcomes in Atrial Fibrillation and Alzheimer’s Disease: Insights from a Swedish Nationwide Study

By MedXY 08/13/2026

This review synthesizes evidence linking NOAC use to slower cognitive decline and improved clinical outcomes in patients with atrial fibrillation and Alzheimer's disease, highlighting advantages over warfarin and non-use.

Neurology news Pathology & Lab Medicine/Bệnh học

Evaluating Antibody Detection Methods in Myasthenia Gravis: Insights from the ADAM Study

By MedXY 08/13/2026

The ADAM Study demonstrates superior diagnostic accuracy of live cell-based assays over fixed cell-based and ELISA tests for detecting AChR antibodies in myasthenia gravis, highlighting important clinical implications for antibody testing strategies.

Neurology news Psychiatry

Unraveling the Neurobiological Pathways Linking Childhood Trauma to Bipolar Disorder: Insights from the ENIGMA Consortium

By MedXY 08/12/2026

An international study reveals that childhood trauma’s association with bipolar disorder is partially mediated by brain morphology changes, particularly in hippocampal volume and frontal cortical thickness.

Neurology news Radiology

Deep Learning-Driven Synthetic MR Perfusion Maps: A Breakthrough in Acute Ischemic Stroke Imaging

By MedXY 08/12/2026

This study presents a deep learning model that generates synthetic T-max perfusion maps from noncontrast DWI and FLAIR sequences, potentially streamlining stroke imaging and eliminating the need for contrast agents.

Neurology news Pathology & Lab Medicine/Bệnh học

Advancing Myasthenia Gravis Diagnosis: The Superior Accuracy of Cell-Based Assays in Antibody Detection

By MedXY 08/12/2026

The ADAM study reveals that live and fixed cell-based assays outperform ELISA in detecting AChR and MuSK antibodies, offering enhanced diagnostic accuracy for myasthenia gravis, particularly in ocular cases.

Neurology news Pathology & Lab Medicine/Bệnh học

Pathology and Genetics in a Global Cohort of Parkinsonian Disorders

By MedXY 08/12/2026

This study analyzes clinicopathological and genetic correlations in Parkinsonian disorders across diverse ancestries, revealing diagnostic challenges, genetic influences, and ancestry-related pathological variations.

Neurology news Respiratory

Brain Structure Changes in Chronic Cough: Insights from a Large-Scale Longitudinal Study

By MedXY 08/11/2026

This large-scale longitudinal study reveals that chronic cough is linked with widespread grey matter volume reductions and accelerated brain atrophy, highlighting potential neurostructural underpinnings of cough hypersensitivity.

Neurology news

Enhancing Stroke Recovery: Adjunctive Normobaric Hyperoxia with Endovascular Thrombectomy in Late-Presenting Large Vessel Occlusion

By MedXY 08/11/2026

A phase IIb trial shows that adding normobaric hyperoxia to endovascular thrombectomy in acute ischemic stroke patients 6 to 24 hours after onset is safe, improves early neurological outcomes, and reduces infarct volume, warranting larger confirmatory studies.

Neurology news Radiology

Brain-Predicted Age Difference Enhances Dementia Risk Stratification in Subjective Cognitive Decline Beyond Standard MRI Assessment

By MedXY 08/11/2026

Brain-predicted age difference (brain-PAD) from MRI improves early dementia risk prediction in patients with subjective cognitive decline, outperforming traditional visual MRI ratings and offering prognostic value beyond amyloid biomarkers, especially in early-stage cognitive impairment.

Cardiology Neurology news

Tailoring Blood Pressure Targets After Endovascular Therapy in Acute Ischemic Stroke: Clinical Trial Insights

By MedXY 08/11/2026

A randomized trial shows reperfusion-guided blood pressure management post-thrombectomy improves functional outcomes and reduces hemorrhagic transformation, supporting personalized BP targets based on reperfusion status.

Neurology news Psychiatry

Connectivity- vs Scalp-Based Targeting of Accelerated Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial

By MedXY 08/10/2026

This randomized trial compared connectivity-based versus scalp-based targeting of accelerated TMS in treatment-resistant depression, showing greater antidepressant effects with individualized connectivity-guided targeting.

Internal Medicine Neurology news

Deciphering the Link Between Postoperative Delirium, Rehospitalization, and Cognitive Decline in Older Adults

By MedXY 08/10/2026

This study investigates whether recurrent hospitalizations mediate the association of postoperative delirium with long-term cognitive decline in seniors after major surgery, finding that rehospitalization does not significantly affect this relationship.

Cardiology Neurology news

Evaluating Low-Dose Colchicine for Preventing Vascular Events After Acute Intracerebral Hemorrhage: Insights from a Placebo-Controlled Pilot Trial

By MedXY 08/09/2026

This pilot randomized trial demonstrates the feasibility of using low-dose colchicine after acute intracerebral hemorrhage to prevent vascular events, highlighting considerations for future larger studies regarding recruitment, adherence, and discontinuation rates.